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A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants A Gusev, K Lawrenson, X Lin, PC Lyra Jr, S Kar, KC Vavra, F Segato, ... Nature genetics 51 (5), 815-823, 2019 | 101 | 2019 |
Super-enhancer-associated LncRNA UCA1 interacts directly with AMOT to activate YAP target genes in epithelial ovarian cancer X Lin, TJ Spindler, MA de Souza Fonseca, RI Corona, JH Seo, FS Dezem, ... IScience 17, 242-255, 2019 | 58 | 2019 |
Optimizing exosomal RNA isolation for RNA-Seq analyses of archival sera specimens EN Prendergast, MA de Souza Fonseca, FS Dezem, J Lester, BY Karlan, ... PLoS One 13 (5), e0196913, 2018 | 56 | 2018 |
A study of high-grade serous ovarian cancer origins implicates the SOX18 transcription factor in tumor development K Lawrenson, MAS Fonseca, AY Liu, FS Dezem, JM Lee, X Lin, ... Cell reports 29 (11), 3726-3735. e4, 2019 | 48 | 2019 |
Predicting master transcription factors from pan-cancer expression data J Reddy, MAS Fonseca, RI Corona, R Nameki, F Segato Dezem, IA Klein, ... Science advances 7 (48), eabf6123, 2021 | 44 | 2021 |
Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women K Lawrenson, F Song, DJ Hazelett, SP Kar, J Tyrer, CM Phelan, ... Gynecologic oncology 153 (2), 343-355, 2019 | 35 | 2019 |
Dual stromal targeting sensitizes pancreatic adenocarcinoma for anti-programmed cell death protein 1 therapy AB Blair, J Wang, J Davelaar, A Baker, K Li, N Niu, J Wang, Y Shao, ... Gastroenterology 163 (5), 1267-1280. e7, 2022 | 25 | 2022 |
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Pleiotropy-guided transcriptome imputation from normal and tumor tissues identifies candidate susceptibility genes for breast and ovarian cancer SP Kar, DPC Considine, JP Tyrer, JT Plummer, S Chen, FS Dezem, ... Human Genetics and Genomics Advances 2 (3), 2021 | 14 | 2021 |
DNA methylation-based signatures classify sporadic pituitary tumors according to clinicopathological features MS Mosella, TS Sabedot, TC Silva, TM Malta, FS Dezem, KP Asmaro, ... Neuro-oncology 23 (8), 1292-1303, 2021 | 10 | 2021 |
Copy number variants are ovarian cancer risk alleles at known and novel risk loci AA DeVries, J Dennis, JP Tyrer, PC Peng, SG Coetzee, AL Reyes, ... JNCI: Journal of the National Cancer Institute 114 (11), 1533-1544, 2022 | 6 | 2022 |
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Incidence and prognostic impact of HER2‐positivity loss after dual HER2‐directed neoadjuvant therapy for HER2+ breast cancer A LeVee, K Spector, B Larkin, F Dezem, J Plummer, F Dadmanesh, S Patil, ... Cancer medicine 12 (9), 10647-10659, 2023 | 4 | 2023 |
US Severe Acute Respiratory Syndrome Coronavirus 2 Epsilon Variant: Highly Transmissible but With an Adjusted Muted Host T-Cell Response JT Plummer, D Contreras, W Zhang, A Binek, R Zhang, F Dezem, ... Clinical Infectious Diseases 75 (11), 1940-1949, 2022 | 4 | 2022 |
Transcriptome and interactome analyses identify the TP53 interacting gene RCCD1 as a candidate susceptibility gene at the 15p26.1 breast and ovarian cancer … J Plummer, FS Dezem, SS Chen, S Dhungana, D Wali, B Davis, J Kanska, ... bioRxiv, 2020.09. 29.319699, 2020 | 2 | 2020 |
Cis-and trans-eQTL TWAS of breast and ovarian cancer identify more than 100 risk associated genes in the BCAC and OCAC consortia ST Head, F Dezem, A Todor, J Yang, J Plummer, S Gayther, S Kar, ... bioRxiv, 2023 | 1 | 2023 |
Multi-Tissue Transcriptome-Wide Association Study Identifies 26 Novel Candidate Susceptibility Genes for High Grade Serous Epithelial Ovarian Cancer A Gusev, K Lawrenson, F Segato, MAS Fonseca, S Kar, KC Vavra, ... bioRxiv, 330613, 2018 | 1 | 2018 |
Spatially Resolved Single-Cell Omics: Methods, Challenges, and Future Perspectives FS Dezem, NS Morosini, W Arjumand, H DuBose, J Plummer Annual Review of Biomedical Data Science 7, 2024 | | 2024 |
Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions EO Dareng, SG Coetzee, JP Tyrer, PC Peng, W Rosenow, S Chen, ... The American Journal of Human Genetics, 2024 | | 2024 |