| Restoring function in exhausted CD8 T cells during chronic viral infection DL Barber, EJ Wherry, D Masopust, B Zhu, JP Allison, AH Sharpe, ... Nature 439 (7077), 682-687, 2006 | 4880 | 2006 |
| T cell exhaustion EJ Wherry Nature immunology 12 (6), 492-499, 2011 | 4311 | 2011 |
| Molecular and cellular insights into T cell exhaustion EJ Wherry, M Kurachi Nature reviews immunology 15 (8), 486-499, 2015 | 3951 | 2015 |
| PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression CL Day, DE Kaufmann, P Kiepiela, JA Brown, ES Moodley, S Reddy, ... Nature 443 (7109), 350-354, 2006 | 3239 | 2006 |
| Effector and memory T-cell differentiation: implications for vaccine development SM Kaech, EJ Wherry, R Ahmed Nature Reviews Immunology 2 (4), 251-262, 2002 | 2371 | 2002 |
| Lineage relationship and protective immunity of memory CD8 T cell subsets EJ Wherry, V Teichgräber, TC Becker, D Masopust, SM Kaech, R Antia, ... Nature immunology 4 (3), 225-234, 2003 | 2354 | 2003 |
| Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection SD Blackburn, H Shin, WN Haining, T Zou, CJ Workman, A Polley, ... Nature immunology 10 (1), 29-37, 2009 | 2339 | 2009 |
| Molecular signature of CD8+ T cell exhaustion during chronic viral infection EJ Wherry, SJ Ha, SM Kaech, WN Haining, S Sarkar, V Kalia, ... Immunity 27 (4), 670-684, 2007 | 2324 | 2007 |
| Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer C Twyman-Saint Victor, AJ Rech, A Maity, R Rengan, KE Pauken, ... Nature 520 (7547), 373-377, 2015 | 2296 | 2015 |
| Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells SM Kaech, JT Tan, EJ Wherry, BT Konieczny, CD Surh, R Ahmed Nature immunology 4 (12), 1191-1198, 2003 | 2296 | 2003 |
| Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response G Chen, AC Huang, W Zhang, G Zhang, M Wu, W Xu, Z Yu, J Yang, ... Nature 560 (7718), 382-386, 2018 | 2080 | 2018 |
| Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment EJ Wherry, JN Blattman, K Murali-Krishna, R Van Der Most, R Ahmed Journal of virology 77 (8), 4911-4927, 2003 | 1918 | 2003 |
| The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection AH Sharpe, EJ Wherry, R Ahmed, GJ Freeman Nature immunology 8 (3), 239-245, 2007 | 1834 | 2007 |
| Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus LA Monticelli, GF Sonnenberg, MC Abt, T Alenghat, CGK Ziegler, ... Nature immunology 12 (11), 1045-1054, 2011 | 1623 | 2011 |
| Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications D Mathew, JR Giles, AE Baxter, DA Oldridge, AR Greenplate, JE Wu, ... Science 369 (6508), eabc8511, 2020 | 1543 | 2020 |
| T-cell invigoration to tumour burden ratio associated with anti-PD-1 response AC Huang, MA Postow, RJ Orlowski, R Mick, B Bengsch, S Manne, W Xu, ... Nature 545 (7652), 60-65, 2017 | 1476 | 2017 |
| Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin AM Intlekofer, N Takemoto, EJ Wherry, SA Longworth, JT Northrup, ... Nature immunology 6 (12), 1236-1244, 2005 | 1459 | 2005 |
| CD8 T cell exhaustion during chronic viral infection and cancer LM McLane, MS Abdel-Hakeem, EJ Wherry Annual review of immunology 37, 457-495, 2019 | 1376 | 2019 |
| Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia JA Fraietta, SF Lacey, EJ Orlando, I Pruteanu-Malinici, M Gohil, S Lundh, ... Nature medicine 24 (5), 563-571, 2018 | 1335 | 2018 |
| Redefining chronic viral infection HW Virgin, EJ Wherry, R Ahmed Cell 138 (1), 30-50, 2009 | 1186 | 2009 |
