Differential outcome of TRIF-mediated signaling in TLR4 and TLR3 induced DC maturation W Hu, A Jain, Y Gao, IM Dozmorov, R Mandraju, EK Wakeland, C Pasare Proceedings of the National Academy of Sciences 112 (45), 13994-13999, 2015 | 74 | 2015 |
IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility R Song, Y Gao, I Dozmorov, V Malladi, I Saha, MM McDaniel, ... Cell reports 34 (12), 2021 | 54 | 2021 |
Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity Y Choi, JN Lichterman, LA Coughlin, N Poulides, W Li, P Del Valle, ... Science immunology 8 (81), eabo2003, 2023 | 25 | 2023 |
Distinct patterns of innate immune activation by clinical isolates of respiratory syncytial virus R Levitz, Y Gao, I Dozmorov, R Song, EK Wakeland, JS Kahn PLoS One 12 (9), e0184318, 2017 | 25 | 2017 |
Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis X Xiao, JP Kennelly, A Ferrari, BL Clifford, E Whang, Y Gao, K Qian, ... Nature metabolism 5 (1), 165-181, 2023 | 18 | 2023 |
Transcriptional profiling identifies caspase-1 as a T cell–intrinsic regulator of Th17 differentiation Y Gao, K Deason, A Jain, RA Irizarry-Caro, I Dozmorov, LA Coughlin, ... Journal of Experimental Medicine 217 (4), 2020 | 17 | 2020 |
Effector memory CD4+ T cells induce damaging innate inflammation and autoimmune pathology by engaging CD40 and TNFR on myeloid cells MM McDaniel, AS Chawla, A Jain, HE Meibers, I Saha, Y Gao, V Jain, ... Science immunology 7 (67), eabk0182, 2022 | 16 | 2022 |
Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus P Raj, R Song, H Zhu, L Riediger, DJ Jun, C Liang, C Arana, B Zhang, ... Genome biology 21, 1-26, 2020 | 9 | 2020 |
MyD88 signaling in T cells is critical for effector CD4 T cell differentiation following a transitional T follicular helper cell stage R Mandraju, A Jain, Y Gao, Z Ouyang, MV Norgard, C Pasare Infection and immunity 86 (5), 10.1128/iai. 00791-17, 2018 | 8 | 2018 |
Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake A Ferrari, E Whang, X Xiao, JP Kennelly, B Romartinez-Alonso, JJ Mack, ... Science 382 (6671), eadf0966, 2023 | 6 | 2023 |
Aster-B–dependent estradiol synthesis protects female mice from diet-induced obesity X Xiao, JP Kennelly, AC Feng, L Cheng, B Romartinez-Alonso, A Bedard, ... The Journal of Clinical Investigation 134 (4), 2024 | 1 | 2024 |
Hepatic GATA4 regulates cholesterol and triglyceride homeostasis in collaboration with LXRs L Bideyan, ML Rodríguez, C Priest, JP Kennelly, Y Gao, A Ferrari, ... Genes & Development 36 (21-24), 1129-1144, 2022 | 1 | 2022 |
Transcriptional profiling of pathogen-specific CD4 T cells reveals key events that regulate Th17 cell priming and differentiation Y Gao, KL Deason, A Jain, I Dozmorov, EK Wakeland, C Pasare The Journal of Immunology 200 (1_Supplement), 47.7-47.7, 2018 | 1 | 2018 |
T cell cholesterol transport is a metabolic checkpoint that links intestinal immune responses to dietary lipid absorption Y Gao, JP Kennelly, X Xiao, E Whang, A Ferrari, AH Bedard, JJ Mack, ... BioRxiv, 584164, 2024 | | 2024 |
Transcriptome profiling of pathogen-specific CD4 T cells identifies T-cell-intrinsic caspase-1 as an important regulator of Th17 differentiation Y Gao, K Deason, A Jain, RA Irizarry-Caro, I Dozmorov, I Rauch, ... bioRxiv, 452763, 2018 | | 2018 |
Temporal transcription analysis of innate immune response to respiratory syncytial virus infection (VIR2P. 1164) Y Gao, R Song, I Dozmorov, K Viswanathan, R Levitz, J Kahn, ... The Journal of Immunology 194 (1_Supplement), 75.3-75.3, 2015 | | 2015 |