Telomerase mutations in families with idiopathic pulmonary fibrosis MY Armanios, JJL Chen, JD Cogan, JK Alder, RG Ingersoll, C Markin, ... New England Journal of Medicine 356 (13), 1317-1326, 2007 | 1564 | 2007 |
Short telomeres are a risk factor for idiopathic pulmonary fibrosis JK Alder, JJL Chen, L Lancaster, S Danoff, S Su, JD Cogan, I Vulto, M Xie, ... Proceedings of the National Academy of Sciences 105 (35), 13051-13056, 2008 | 881 | 2008 |
Secondary structure of vertebrate telomerase RNA JL Chen, MA Blasco, CW Greider Cell 100 (5), 503-514, 2000 | 823 | 2000 |
Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita M Armanios, JL Chen, YPC Chang, RA Brodsky, A Hawkins, CA Griffin, ... Proceedings of the National Academy of Sciences 102 (44), 15960-15964, 2005 | 556 | 2005 |
The telomerase database JD Podlevsky, CJ Bley, RV Omana, X Qi, JJL Chen Nucleic acids research 36 (suppl_1), D339-D343, 2007 | 263 | 2007 |
A critical stem–loop structure in the CR4–CR5 domain of mammalian telomerase RNA JL Chen, KK Opperman, CW Greider Nucleic acids research 30 (2), 592-597, 2002 | 209 | 2002 |
Telomerase RNA structure and function: implications for dyskeratosis congenita JL Chen, CW Greider Trends in biochemical sciences 29 (4), 183-192, 2004 | 205 | 2004 |
Template boundary definition in mammalian telomerase JL Chen, CW Greider Genes & development 17 (22), 2747-2752, 2003 | 194 | 2003 |
Identification of the universally conserved core of ribonuclease P RNA. JL Chen, NR Pace Rna 3 (6), 557, 1997 | 183 | 1997 |
Functional analysis of the pseudoknot structure in human telomerase RNA JL Chen, CW Greider Proceedings of the National Academy of Sciences 102 (23), 8080-8085, 2005 | 181 | 2005 |
It all comes together at the ends: telomerase structure, function, and biogenesis JD Podlevsky, JJL Chen Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 730 (1 …, 2012 | 179 | 2012 |
Telomerase mutations in smokers with severe emphysema SE Stanley, JJL Chen, JD Podlevsky, JK Alder, NN Hansel, RA Mathias, ... The Journal of clinical investigation 125 (2), 563-570, 2015 | 176 | 2015 |
Syndrome complex of bone marrow failure and pulmonary fibrosis predicts germline defects in telomerase EM Parry, JK Alder, X Qi, JJL Chen, M Armanios Blood, The Journal of the American Society of Hematology 117 (21), 5607-5611, 2011 | 172 | 2011 |
Evolution of vault RNAs PF Stadler, JJL Chen, J Hackermüller, S Hoffmann, F Horn, P Khaitovich, ... Molecular biology and evolution 26 (9), 1975-1991, 2009 | 172 | 2009 |
Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross‐species incompatibility JL Chen, CW Greider The EMBO Journal, 2003 | 166 | 2003 |
Comparative photocross‐linking analysis of the tertiary structures of Escherichia coli and Bacillus subtilis RNase P RNAs JL Chen, JM Nolan, ME Harris, NR Pace The EMBO Journal, 1998 | 155 | 1998 |
An emerging consensus for telomerase RNA structure JL Chen, CW Greider Proceedings of the National Academy of Sciences 101 (41), 14683-14684, 2004 | 136 | 2004 |
Ancestral mutation in telomerase causes defects in repeat addition processivity and manifests as familial pulmonary fibrosis JK Alder, JD Cogan, AF Brown, CJ Anderson, WE Lawson, PM Lansdorp, ... PLoS genetics 7 (3), e1001352, 2011 | 128 | 2011 |
Analysis of the tertiary structure of the ribonuclease P ribozyme-substrate complex by site-specific photoaffinity crosslinking. ME Harris, AV Kazantsev, JL Chen, NR Pace Rna 3 (6), 561-576, 1997 | 126 | 1997 |
Evolutionary perspectives of telomerase RNA structure and function JD Podlevsky, JJL Chen RNA biology 13 (8), 720-732, 2016 | 109 | 2016 |