Mirko Paiardini
Mirko Paiardini
Associate Professor, Emory University
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Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections
JM Brenchley, M Paiardini, KS Knox, AI Asher, B Cervasi, TE Asher, ...
Blood, The Journal of the American Society of Hematology 112 (7), 2826-2835, 2008
Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia
G Silvestri, DL Sodora, RA Koup, M Paiardini, SP O'Neil, HM McClure, ...
Immunity 18 (3), 441-452, 2003
Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections
JD Estes, LD Harris, NR Klatt, B Tabb, S Pittaluga, M Paiardini, ...
PLoS pathogens 6 (8), e1001052, 2010
HIV‐associated chronic immune activation
M Paiardini, M Müller‐Trutwin
Immunological reviews 254 (1), 78-101, 2013
Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys
SE Bosinger, Q Li, SN Gordon, NR Klatt, L Duan, L Xu, N Francella, ...
The Journal of clinical investigation 119 (12), 3556-3572, 2009
Natural SIV hosts: showing AIDS the door
A Chahroudi, SE Bosinger, TH Vanderford, M Paiardini, G Silvestri
Science 335 (6073), 1188-1193, 2012
Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys
SN Gordon, NR Klatt, SE Bosinger, JM Brenchley, JM Milush, JC Engram, ...
The Journal of Immunology 179 (5), 3026-3034, 2007
Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals
M Paiardini, B Cervasi, H Albrecht, A Muthukumar, R Dunham, S Gordon, ...
The Journal of Immunology 174 (5), 2900-2909, 2005
Understanding the benign nature of SIV infection in natural hosts
G Silvestri, M Paiardini, I Pandrea, MM Lederman, DL Sodora
The Journal of clinical investigation 117 (11), 3148-3154, 2007
Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection
NR Klatt, JD Estes, X Sun, AM Ortiz, JS Barber, LD Harris, B Cervasi, ...
Mucosal immunology 5 (6), 646-657, 2012
Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV …
LD Harris, B Tabb, DL Sodora, M Paiardini, NR Klatt, DC Douek, ...
Journal of virology 84 (15), 7886-7891, 2010
Low levels of SIV infection in sooty mangabey central memory CD4+ T cells are associated with limited CCR5 expression
M Paiardini, B Cervasi, E Reyes-Aviles, L Micci, AM Ortiz, A Chahroudi, ...
Nature medicine 17 (7), 830-836, 2011
CD8+ lymphocytes are required for maintaining viral suppression in SIV-infected macaques treated with short-term antiretroviral therapy
EK Cartwright, L Spicer, SA Smith, D Lee, R Fast, S Paganini, BO Lawson, ...
Immunity 45 (3), 656-668, 2016
Mucosal immune dysfunction in AIDS pathogenesis.
M Paiardini, I Frank, I Pandrea, C Apetrei, G Silvestri
AIDS reviews 10 (1), 36-46, 2008
CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells
NR Klatt, E Shudo, AM Ortiz, JC Engram, M Paiardini, B Lawson, ...
PLoS pathogens 6 (1), e1000747, 2010
Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques
TN Hoang, M Pino, AK Boddapati, EG Viox, CE Starke, AA Upadhyay, ...
Cell 184 (2), 460-475. e21, 2021
Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals
SN Gordon, B Cervasi, P Odorizzi, R Silverman, F Aberra, G Ginsberg, ...
The Journal of Immunology 185 (9), 5169-5179, 2010
CTLA-4+ PD-1− memory CD4+ T cells critically contribute to viral persistence in antiretroviral therapy-suppressed, SIV-infected rhesus macaques
CS McGary, C Deleage, J Harper, L Micci, SP Ribeiro, S Paganini, ...
Immunity 47 (4), 776-788. e5, 2017
Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
JB McBrien, M Mavigner, L Franchitti, SA Smith, E White, GK Tharp, ...
Nature 578 (7793), 154-159, 2020
CD127 and CD25 Expression Defines CD4+ T Cell Subsets That Are Differentially Depleted during HIV Infection
RM Dunham, B Cervasi, JM Brenchley, H Albrecht, A Weintrob, B Sumpter, ...
The Journal of Immunology 180 (8), 5582-5592, 2008
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