The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute … RE Gale, C Green, C Allen, AJ Mead, AK Burnett, RK Hills, DC Linch Blood, The Journal of the American Society of Hematology 111 (5), 2776-2784, 2008 | 955 | 2008 |
Mutation of the Wilms’ tumor 1 gene is a poor prognostic factor associated with chemotherapy resistance in normal karyotype acute myeloid leukemia: the United Kingdom Medical … P Virappane, R Gale, R Hills, I Kakkas, K Summers, J Stevens, C Allen, ... Journal of Clinical Oncology 26 (33), 5429-5435, 2008 | 274 | 2008 |
TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis D Bowen, MJ Groves, AK Burnett, Y Patel, C Allen, C Green, RE Gale, ... Leukemia 23 (1), 203-206, 2009 | 228 | 2009 |
The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia C Allen, RK Hills, K Lamb, C Evans, S Tinsley, R Sellar, M O'brien, JL Yin, ... Leukemia 27 (9), 1891-1901, 2013 | 167 | 2013 |
Genetically distinct leukemic stem cells in human CD34− acute myeloid leukemia are arrested at a hemopoietic precursor-like stage L Quek, GW Otto, C Garnett, L Lhermitte, D Karamitros, B Stoilova, IJ Lau, ... Journal of Experimental Medicine 213 (8), 1513-1535, 2016 | 165 | 2016 |
WT1 mutations in T-ALL V Tosello, MR Mansour, K Barnes, M Paganin, ML Sulis, S Jenkinson, ... Blood, The Journal of the American Society of Hematology 114 (5), 1038-1045, 2009 | 149 | 2009 |
Prognostic implications of NOTCH1 and FBXW7 mutations in adults with T-cell acute lymphoblastic leukemia treated on the MRC UKALLXII/ECOG E2993 protocol MR Mansour, ML Sulis, V Duke, L Foroni, S Jenkinson, K Koo, CG Allen, ... Journal of clinical oncology 27 (26), 4352, 2009 | 143 | 2009 |
Simpson's paradox and the impact of different DNMT3A mutations on outcome in younger adults with acute myeloid leukemia RE Gale, K Lamb, C Allen, D El-Sharkawi, C Stowe, S Jenkinson, ... Journal of Clinical Oncology 33 (18), 2072-2083, 2015 | 108 | 2015 |
Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia M Gupta, M Raghavan, RE Gale, C Chelala, C Allen, G Molloy, T Chaplin, ... Genes, Chromosomes and Cancer 47 (9), 729-739, 2008 | 95 | 2008 |
Notch-1 mutations are secondary events in some patients with T-cell acute lymphoblastic leukemia MR Mansour, V Duke, L Foroni, B Patel, CG Allen, PJ Ancliff, RE Gale, ... Clinical cancer research 13 (23), 6964-6969, 2007 | 91 | 2007 |
Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia S Rahman, M Magnussen, TE León, N Farah, Z Li, BJ Abraham, KZ Alapi, ... Blood, The Journal of the American Society of Hematology 129 (24), 3221-3226, 2017 | 80 | 2017 |
Prevalence and timing of TP53 mutations in del (17p) myeloma and effect on survival M Chin, JI Sive, C Allen, C Roddie, SJ Chavda, D Smith, P Blombery, ... Blood cancer journal 7 (9), e610-e610, 2017 | 62 | 2017 |
Low-cost, high-throughput sequencing of DNA assemblies using a highly multiplexed Nextera process EB Shapland, V Holmes, CD Reeves, E Sorokin, M Durot, D Platt, C Allen, ... ACS synthetic biology 4 (7), 860-866, 2015 | 61 | 2015 |
Executive dysfunction predicts social cognition impairment in amyotrophic lateral sclerosis TJ Watermeyer, RG Brown, KCL Sidle, DJ Oliver, C Allen, J Karlsson, ... Journal of neurology 262, 1681-1690, 2015 | 58 | 2015 |
Impact of disease, cognitive and behavioural factors on caregiver outcome in amyotrophic lateral sclerosis TJ Watermeyer, RG Brown, KCL Sidle, DJ Oliver, C Allen, J Karlsson, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 16 (5-6), 316-323, 2015 | 47 | 2015 |
Medical Research Council Adult Leukaemia Working Party. The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a … RE Gale, C Green, C Allen, AJ Mead, AK Burnett, RK Hills, DC Linch Blood 111 (5), 2776-2784, 2008 | 46 | 2008 |
The cellular and molecular mechanisms for neutropenia in Barth syndrome V Makaryan, W Kulik, FM Vaz, C Allen, Y Dror, DC Dale, AA Aprikyan European journal of haematology 88 (3), 195-209, 2012 | 41 | 2012 |
Characterization of a novel ACE2-based therapeutic with enhanced rather than reduced activity against SARS-CoV-2 variants M Ferrari, L Mekkaoui, FT Ilca, Z Akbar, R Bughda, K Lamb, K Ward, ... Journal of Virology 95 (19), 10.1128/jvi. 00685-21, 2021 | 35 | 2021 |
Beach litter sourcing: A trawl along the Northern Ireland coastline AT Williams, P Randerson, C Allen, JAG Cooper Marine Pollution Bulletin 122 (1-2), 47-64, 2017 | 32 | 2017 |
KIR gene haplotype: an independent predictor of clinical outcome in MDS patients K Stringaris, D Marin, AJ Barrett, R Hills, C Sobieski, K Cao, JG Saltarrelli, ... Blood, The Journal of the American Society of Hematology 128 (24), 2819-2823, 2016 | 32 | 2016 |