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Hee-Bum Kang
Hee-Bum Kang
Vice-director, New drug Research Institute, HLB Lifescience
Verified email at hlb-ls.com
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Cited by
Cited by
Year
Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth
T Hitosugi, L Zhou, S Elf, J Fan, HB Kang, JH Seo, C Shan, Q Dai, ...
Cancer cell 22 (5), 585-600, 2012
4342012
Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation
KC Choi, MG Jung, YH Lee, JC Yoon, SH Kwon, HB Kang, MJ Kim, ...
Cancer research 69 (2), 583-592, 2009
3862009
Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth
L Jin, D Li, GN Alesi, J Fan, HB Kang, Z Lu, TJ Boggon, P Jin, H Yi, ...
Cancer cell 27 (2), 257-270, 2015
3292015
Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex
J Fan, C Shan, HB Kang, S Elf, J Xie, M Tucker, TL Gu, M Aguiar, ...
Molecular cell 53 (4), 534-548, 2014
2902014
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling
R Lin, S Elf, C Shan, HB Kang, Q Ji, L Zhou, T Hitosugi, L Zhang, S Zhang, ...
Nature cell biology 17 (11), 1484-1496, 2015
2682015
Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation
J Wang, C Luo, C Shan, Q You, J Lu, S Elf, Y Zhou, Y Wen, JL Vinkenborg, ...
Nature chemistry 7 (12), 968-979, 2015
2272015
Prevention of dietary-fat-fueled ketogenesis attenuates BRAF V600E tumor growth
S Xia, R Lin, L Jin, L Zhao, HB Kang, Y Pan, S Liu, G Qian, Z Qian, ...
Cell metabolism 25 (2), 358-373, 2017
1602017
Metabolic rewiring by oncogenic BRAF V600E links ketogenesis pathway to BRAF-MEK1 signaling
HB Kang, J Fan, R Lin, S Elf, Q Ji, L Zhao, L Jin, JH Seo, C Shan, ...
Molecular cell 59 (3), 345-358, 2015
1482015
Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth
C Shan, S Elf, Q Ji, HB Kang, L Zhou, T Hitosugi, L Jin, R Lin, L Zhang, ...
Molecular cell 55 (4), 552-565, 2014
1412014
MAST1 drives cisplatin resistance in human cancers by rewiring cRaf-independent MEK activation
L Jin, J Chun, C Pan, D Li, R Lin, GN Alesi, X Wang, HB Kang, L Song, ...
Cancer cell 34 (2), 315-330. e7, 2018
1092018
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation
T Hitosugi, L Zhou, J Fan, S Elf, L Zhang, J Xie, Y Wang, TL Gu, ...
Nature communications 4 (1), 1790, 2013
982013
Transcriptional regulation of the transforming growth factor β type II receptor gene by histone acetyltransferase and deacetylase is mediated by NF-Y in human breast cancer cells
SH Park, SR Lee, BC Kim, EA Cho, SP Patel, HB Kang, EA Sausville, ...
Journal of Biological Chemistry 277 (7), 5168-5174, 2002
912002
HDAC3 selectively represses CREB3-mediated transcription and migration of metastatic breast cancer cells
HC Kim, KC Choi, HK Choi, HB Kang, MJ Kim, YH Lee, OH Lee, J Lee, ...
Cellular and molecular life sciences 67, 3499-3510, 2010
902010
Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect
J Fan, HB Kang, C Shan, S Elf, R Lin, J Xie, TL Gu, M Aguiar, S Lonning, ...
Journal of Biological Chemistry 289 (38), 26533-26541, 2014
872014
Tyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth
C Shan, HB Kang, S Elf, J Xie, TL Gu, M Aguiar, S Lonning, T Hitosugi, ...
Journal of Biological Chemistry 289 (31), 21413-21422, 2014
712014
The histone methyltransferase, NSD2, enhances androgen receptor-mediated transcription
HB Kang, Y Choi, JM Lee, KC Choi, HC Kim, JY Yoo, YH Lee, HG Yoon
FEBS letters 583 (12), 1880-1886, 2009
702009
Effect of anti-histone acetyltransferase activity from Rosa rugosa Thunb.(Rosaceae) extracts on androgen receptor-mediated transcriptional regulation
YH Lee, MG Jung, HB Kang, KC Choi, S Haam, W Jun, YJ Kim, HY Cho, ...
Journal of ethnopharmacology 118 (3), 412-417, 2008
562008
PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death
HK Choi, Y Choi, HB Kang, E Lim, SY Park, HS Lee, JM Park, J Moon, ...
Human Molecular Genetics 24 (4), 1127-1141, 2015
492015
Presence of human mycoplasma DNA in gastric tissue samples from Korean chronic gastritis patients
HJ Kwon, JO Kang, SH Cho, HB Kang, KA Kang, JK Kim, YS Kang, ...
Cancer science 95 (4), 311-315, 2004
402004
HMG-CoA synthase 1 is a synthetic lethal partner of BRAFV600E in human cancers
L Zhao, J Fan, S Xia, Y Pan, S Liu, G Qian, Z Qian, HB Kang, JL Arbiser, ...
Journal of Biological Chemistry 292 (24), 10142-10152, 2017
362017
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