Mechanism of structural transformations induced by antimicrobial peptides in lipid membranes KLH Lam, H Wang, TA Siaw, MR Chapman, AJ Waring, JT Kindt, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (2), 194-204, 2012 | 66 | 2012 |
Amyloid-β fibrillogenesis seeded by interface-induced peptide misfolding and self-assembly EY Chi, SL Frey, A Winans, KLH Lam, K Kjaer, J Majewski, KYC Lee Biophysical Journal 98 (10), 2299-2308, 2010 | 65 | 2010 |
Mechanism of supported membrane disruption by antimicrobial peptide protegrin-1 KLH Lam, Y Ishitsuka, Y Cheng, K Chien, AJ Waring, RI Lehrer, KYC Lee The Journal of Physical Chemistry B 110 (42), 21282-21286, 2006 | 60 | 2006 |
Identifying mutation hotspots reveals pathogenetic mechanisms of KCNQ2 epileptic encephalopathy J Zhang, EC Kim, C Chen, E Procko, S Pant, K Lam, J Patel, R Choi, ... Scientific reports 10 (1), 4756, 2020 | 50 | 2020 |
Aberrant expression of a non-muscle RBFOX2 isoform triggers cardiac conduction defects in myotonic dystrophy C Misra, S Bangru, F Lin, K Lam, SN Koenig, ER Lubbers, J Hedhli, ... Developmental cell 52 (6), 748-763. e6, 2020 | 32 | 2020 |
Beyond electrostatics: Antimicrobial peptide selectivity and the influence of cholesterol-mediated fluidity and lipid chain length on protegrin-1 activity JM Henderson, NS Iyengar, KLH Lam, E Maldonado, T Suwatthee, I Roy, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1861 (10), 182977, 2019 | 26 | 2019 |
Water soluble thiazolyl peptide derivatives B Naidu, W Li, K Lam, M Sorenson, J Wichtowski, T Connolly, Y Ueda, ... US Patent App. 09/928,468, 2002 | 23 | 2002 |
Main-chain mutagenesis reveals intrahelical coupling in an ion channel voltage-sensor DT Infield, K Matulef, JD Galpin, K Lam, E Tajkhorshid, CA Ahern, ... Nature communications 9 (1), 5055, 2018 | 17 | 2018 |
Membrane interactions of Cy3 and Cy5 fluorophores and their effects on membrane-protein dynamics K Lam, E Tajkhorshid Biophysical journal 119 (1), 24-34, 2020 | 14 | 2020 |
PIP2-dependent coupling of voltage sensor and pore domains in Kv7.2 channel S Pant, J Zhang, EC Kim, K Lam, HJ Chung, E Tajkhorshid Communications biology 4 (1), 1189, 2021 | 7 | 2021 |
Rich spectrum of neural field dynamics in the presence of short-term synaptic depression H Wang, K Lam, CCA Fung, KYM Wong, S Wu Physical Review E 92 (3), 032908, 2015 | 7 | 2015 |
Resolution enhancement in neural networks with dynamical synapses CCA Fung, H Wang, K Lam, KYM Wong, S Wu Frontiers in Computational Neuroscience 7, 73, 2013 | 6 | 2013 |
The origin of antimicrobial resistance and fluidity dependent membrane structural transformation by antimicrobial peptide Protegrin-1 MR Chapman, KLH Lam, AJ Waring, RI Lehrer, KYC Lee Biophysical Journal 96 (3), 550a, 2009 | 3 | 2009 |
Backbone amides are determinants of Cl− selectivity in CLC ion channels L Leisle, K Lam, S Dehghani-Ghahnaviyeh, E Fortea, JD Galpin, ... Nature communications 13 (1), 7508, 2022 | 2 | 2022 |
Computational Modeling of Sodium Channel Inactivation K Lam, Z Wu, K Schulten Biophysical Journal 110 (3), 108a, 2016 | 1 | 2016 |
Computational studies of membrane proteins: Structure, function and dynamics K Lam University of Illinois at Urbana-Champaign, 2020 | | 2020 |
Anionic Lipids Modulate Structure and Function of Epilepsy-Causing Voltage-Gated Potassium Channel S Pant, J Zhang, EC Kim, K Lam, HJ Chung, E Tajkhorshid Biophysical Journal 118 (3), 333a, 2020 | | 2020 |
Overexpression of a non-muscle RBFOX2 isoform triggers cardiac conduction defects in myotonic dystrophy C Misra, S Bangru, F Lin, K Lam, SN Koenig, ER Lubbers, J Hedhli, ... bioRxiv, 649715, 2019 | | 2019 |
CY3/CY5 Fluorophore-Lipid Interactions and their Effects on Membrane Protein Dynamics K Lam, E Tajkhorshid Biophysical Journal 114 (3), 278a, 2018 | | 2018 |
Molecular Basis of Neuronal Signaling K Lam, Z Wu, K Schulten Biophysical Journal 108 (2), 151a, 2015 | | 2015 |