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Hazel Quek
Hazel Quek
Research Fellow
Verified email at qimrberghofer.edu.au
Title
Cited by
Cited by
Year
A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype
H Quek, J Luff, KG Cheung, S Kozlov, M Gatei, CS Lee, MC Bellingham, ...
Human molecular genetics 26 (1), 109-123, 2017
812017
Altered brain endothelial cell phenotype from a familial Alzheimer mutation and its potential implications for amyloid clearance and drug delivery
LE Oikari, R Pandit, R Stewart, C Cuní-López, H Quek, R Sutharsan, ...
Stem cell reports 14 (5), 924-939, 2020
702020
Chronic stress and A lzheimer's disease: the interplay between the hypothalamic–pituitary–adrenal axis, genetics and microglia
A Milligan Armstrong, T Porter, H Quek, A White, J Haynes, C Jackaman, ...
Biological Reviews 96 (5), 2209-2228, 2021
522021
ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression
H Quek, C Cuní-López, R Stewart, T Colletti, A Notaro, TH Nguyen, Y Sun, ...
Journal of neuroinflammation 19 (1), 1-21, 2022
512022
Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage
H Quek, J Luff, KG Cheung, S Kozlov, M Gatei, CS Lee, MC Bellingham, ...
Journal of Leucocyte Biology 101 (4), 927-947, 2017
412017
The Syk–NFAT–IL-2 pathway in dendritic cells is required for optimal sterile immunity elicited by alum adjuvants
HJ Khameneh, AWS Ho, R Spreafico, H Derks, HQY Quek, A Mortellaro
The Journal of Immunology 198 (1), 196-204, 2017
292017
CuII(atsm) Attenuates Neuroinflammation
XY Choo, JR Liddell, MT Huuskonen, A Grubman, D Moujalled, J Roberts, ...
Frontiers in neuroscience 12, 668, 2018
242018
Dual targeting of chromatin stability by the curaxin CBL0137 and histone deacetylase inhibitor panobinostat shows significant preclinical efficacy in neuroblastoma
L Xiao, K Somers, J Murray, R Pandher, M Karsa, E Ronca, A Bongers, ...
Clinical Cancer Research 27 (15), 4338-4352, 2021
182021
Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore
YC Lim, KS Ensbey, C Offenhäuser, RCJ D’souza, JK Cullen, BW Stringer, ...
Neuro-oncology 22 (2), 216-228, 2020
152020
PIKK ing a way to regulate inflammation
H Quek, YC Lim, MF Lavin, TL Roberts
Immunology and cell biology 96 (1), 8-20, 2018
132018
The role of chaperone-mediated autophagy in Bortezomib resistant multiple myeloma
N Nikesitch, P Rebeiro, LL Ho, S Pothula, XM Wang, T Khong, H Quek, ...
Cells 10 (12), 3464, 2021
122021
Recent advances in microglia modelling to address translational outcomes in neurodegenerative diseases
C Cuní-López, R Stewart, H Quek, AR White
Cells 11 (10), 1662, 2022
92022
An Alzheimer’s disease patient-derived olfactory stem cell model identifies gene expression changes associated with cognition
LM Rantanen, M Bitar, R Lampinen, R Stewart, H Quek, LE Oikari, ...
Cells 11 (20), 3258, 2022
72022
SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress
U Ho, J Luff, A James, CS Lee, H Quek, HC Lai, S Apte, YC Lim, MF Lavin, ...
Journal of Cellular and Molecular Medicine 23 (12), 8151-8160, 2019
72019
ATM inhibition prevents interleukin-6 from contributing to the proliferation of glioblastoma cells after ionizing radiation
YC Lim, H Quek, C Offenhäuser, S Fazry, A Boyd, M Lavin, T Roberts, ...
Journal of Neuro-Oncology 138, 509-518, 2018
62018
Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone–Pyridylhydrazone Copper (II) Complex
XY Choo, LE McInnes, A Grubman, JM Wasielewska, I Belaya, E Burrows, ...
International Journal of Molecular Sciences 23 (18), 10722, 2022
52022
3D models of Alzheimer’s disease patient microglia recapitulate disease phenotype and show differential drug responses compared to 2D
C Cuní-López, H Quek, LE Oikari, R Stewart, TH Nguyen, Y Sun, CC Guo, ...
bioRxiv, 2021.03. 17.435758, 2021
52021
A robust approach to differentiate human monocyte-derived microglia from peripheral blood mononuclear cells
H Quek, C Cuní-López, R Stewart, YC Lim, TL Roberts, AR White
STAR protocols 3 (4), 101747, 2022
32022
Regulation of RNA degradation pathways during the lipopolysaccharide response in Macrophages
HC Lai, A James, J Luff, P De Souza, H Quek, U Ho, MF Lavin, TL Roberts
Journal of Leucocyte Biology 109 (3), 593-603, 2021
32021
Patient-specific monocyte-derived microglia as a screening tool for neurodegenerative diseases
H Quek, AR White
Neural Regeneration Research 18 (5), 955-958, 2023
12023
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