| Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency K Cong, M Peng, AN Kousholt, WTC Lee, S Lee, S Nayak, J Krais, ... Molecular cell 81 (15), 3128-3144. e7, 2021 | 218 | 2021 |
| Replication Gaps Underlie BRCA Deficiency and Therapy Response NJ Panzarino, JJ Krais, K Cong, M Peng, M Mosqueda, SU Nayak, ... Cancer research 81 (5), 1388-1397, 2021 | 135 | 2021 |
| Inhibition of the translesion synthesis polymerase REV1 exploits replication gaps as a cancer vulnerability S Nayak, JA Calvo, K Cong, M Peng, E Berthiaume, J Jackson, AM Zaino, ... Science advances 6 (24), eaaz7808, 2020 | 94 | 2020 |
| Opposing roles of FANCJ and HLTF protect forks and restrain replication during stress M Peng, K Cong, NJ Panzarino, S Nayak, J Calvo, B Deng, LJ Zhu, ... Cell reports 24 (12), 3251-3261, 2018 | 68 | 2018 |
| Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps MP Dias, V Tripathi, I van der Heijden, K Cong, EM Manolika, J Bhin, ... Molecular cell 81 (22), 4692-4708. e9, 2021 | 53 | 2021 |
| Exploiting replication gaps for cancer therapy K Cong, SB Cantor Molecular cell 82 (13), 2363-2369, 2022 | 36 | 2022 |
| PARPi synthetic lethality derives from replication-associated single-stranded DNA gaps K Cong, AN Kousholt, M Peng, NJ Panzarino, WTC Lee, S Nayak, J Krais, ... BioRxiv, 781989, 2019 | 23 | 2019 |
| FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells K Cong, N MacGilvary, S Lee, SG MacLeod, J Calvo, M Peng, ... Nature Communications 15 (1), 2599, 2024 | 2 | 2024 |
| Loss of nuclear DNA ligase III can revert PARP inhibitor resistance in BRCA1-deficient cells by increasing DNA replication stress MP Dias, V Tripathi, I van der Heijden, K Cong, EM Manolika, P Galanos, ... bioRxiv, 2021.03. 24.436323, 2021 | 2 | 2021 |
| Prediction of cancer therapy efficacy SB Cantor, N Panzarino, K Cong, M Bere, S Nayak US Patent App. 17/629,893, 2022 | | 2022 |
| A Study of Single-stranded DNA Gaps in the Response to Replication Stress and Synthetic Lethality K Cong | | 2022 |
Sharon CantorUniversity of MassachusettsVerified email at umassmed.edu
