| Structural basis for the activation of 20S proteasomes by 11S regulators FG Whitby, EI Masters, L Kramer, JR Knowlton, Y Yao, CC Wang, CP Hill Nature 408 (6808), 115-120, 2000 | 650 | 2000 |
| Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress K Zaugg, Y Yao, PT Reilly, K Kannan, R Kiarash, J Mason, P Huang, ... Genes & development 25 (10), 1041-1051, 2011 | 519 | 2011 |
| Functional characterization of CFI-400945, a Polo-like kinase 4 inhibitor, as a potential anticancer agent JM Mason, DCC Lin, X Wei, Y Che, Y Yao, R Kiarash, DW Cescon, ... Cancer cell 26 (2), 163-176, 2014 | 183 | 2014 |
| Activation of family C G-protein-coupled receptors by the tripeptide glutathione M Wang, Y Yao, D Kuang, DR Hampson Journal of Biological Chemistry 281 (13), 8864-8870, 2006 | 170 | 2006 |
| Cloning and characterization of a Family C orphan G‐protein coupled receptor D Kuang, Y Yao, J Lam, RG Tsushima, DR Hampson Journal of neurochemistry 93 (2), 383-391, 2005 | 151 | 2005 |
| AZD5153: a novel bivalent BET bromodomain inhibitor highly active against hematologic malignancies GW Rhyasen, MM Hattersley, Y Yao, A Dulak, W Wang, P Petteruti, ... Molecular cancer therapeutics 15 (11), 2563-2574, 2016 | 146 | 2016 |
| Both the isomerase and chaperone activities of protein disulfide isomerase are required for the reactivation of reduced and denatured acidic phospholipase A2 Y Yao, Y Zhou, C Wang The EMBO journal, 1997 | 144 | 1997 |
| Potent and selective bivalent inhibitors of BET bromodomains MJ Waring, H Chen, AA Rabow, G Walker, R Bobby, S Boiko, ... Nature chemical biology 12 (12), 1097-1104, 2016 | 137 | 2016 |
| Structural and functional characterizations of the proteasome-activating protein PA26 from Trypanosoma brucei Y Yao, L Huang, A Krutchinsky, ML Wong, KG Standing, AL Burlingame, ... Journal of Biological Chemistry 274 (48), 33921-33930, 1999 | 84 | 1999 |
| An easily dissociated 26 S proteasome catalyzes an essential ubiquitin-mediated protein degradation pathway in Trypanosoma brucei* 210 Z Li, CB Zou, Y Yao, MA Hoyt, S McDonough, ZB Mackey, P Coffino, ... Journal of Biological Chemistry 277 (18), 15486-15498, 2002 | 75 | 2002 |
| The Discovery of PLK4 Inhibitors: (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-ones as Novel Antiproliferative Agents R Laufer, B Forrest, SW Li, Y Liu, P Sampson, L Edwards, Y Lang, ... Journal of medicinal chemistry 56 (15), 6069-6087, 2013 | 73 | 2013 |
| Molecular similarities in the ligand binding pockets of an odorant receptor and the metabotropic glutamate receptors D Kuang, Y Yao, M Wang, N Pattabiraman, LP Kotra, DR Hampson Journal of Biological Chemistry 278 (43), 42551-42559, 2003 | 62 | 2003 |
| Membrane fusion activity of vesicular stomatitis virus glycoprotein G is induced by low pH but not by heat or denaturant Y Yao, K Ghosh, RF Epand, RM Epand, HP Ghosh Virology 310 (2), 319-332, 2003 | 61 | 2003 |
| α5 subunit in Trypanosoma brucei proteasome can self-assemble to form a cylinder of four stacked heptamer rings Y YAO, CR TOTH, L HUANG, ML WONG, P DIAS, AL BURLINGAME, ... Biochemical journal 344 (2), 349-358, 1999 | 60 | 1999 |
| Ancestral reconstruction of the ligand-binding pocket of Family CG protein-coupled receptors D Kuang, Y Yao, D MacLean, M Wang, DR Hampson, BSW Chang Proceedings of the National Academy of Sciences 103 (38), 14050-14055, 2006 | 57 | 2006 |
| The neuroactive peptide N-acetylaspartylglutamate is not an agonist at the metabotropic glutamate receptor subtype 3 of metabotropic glutamate receptor M Chopra, Y Yao, TJ Blake, DR Hampson, EC Johnson Journal of Pharmacology and Experimental Therapeutics 330 (1), 212-219, 2009 | 55 | 2009 |
| BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer and confers sensitivity to BET inhibitors GW Rhyasen, Y Yao, J Zhang, A Dulak, L Castriotta, K Jacques, W Zhao, ... PLoS One 13 (7), e0200826, 2018 | 52 | 2018 |
| Molecular basis for the differential agonist affinities of group III metabotropic glutamate receptors E Rosemond, M Wang, Y Yao, L Storjohann, T Stormann, EC Johnson, ... Molecular pharmacology 66 (4), 834-842, 2004 | 51 | 2004 |
| Molecular modeling and mutagenesis of the ligand‐binding pocket of the mGlu3 subtype of metabotropic glutamate receptor Y Yao, N Pattabiraman, WF Michne, XP Huang, DR Hampson Journal of neurochemistry 86 (4), 947-957, 2003 | 39 | 2003 |
| Assay for enzyme activity by following the absorbance change of pH-indicators Y Yao, MH Wang, KY Zhao, CC Wang Journal of biochemical and biophysical methods 36 (2-3), 119-130, 1998 | 22 | 1998 |
