Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics L Lucaroni, T Georgiev, E Prodi, S Puglioli, C Pellegrino, N Favalli, L Prati, ... European Journal of Nuclear Medicine and Molecular Imaging 50 (3), 957-961, 2023 | 24 | 2023 |
Selective tumor targeting enabled by picomolar fibroblast activation protein inhibitors isolated from a DNA-encoded affinity maturation library S Puglioli, E Schmidt, C Pellegrino, L Prati, S Oehler, R De Luca, ... Chem 9 (2), 411-429, 2023 | 11 | 2023 |
Design and synthesis of the first indole-based blockers of Panx-1 channel L Crocetti, G Guerrini, S Puglioli, MP Giovannoni, LDC Mannelli, ... European journal of medicinal chemistry 223, 113650, 2021 | 11 | 2021 |
A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition S Oehler, L Lucaroni, F Migliorini, A Elsayed, L Prati, S Puglioli, M Matasci, ... Nature Chemistry 15 (10), 1431-1443, 2023 | 7 | 2023 |
Impact of library input on the hit discovery rate in DNA-encoded chemical library selections S Puglioli, S Oehler, L Prati, J Scheuermann, G Bassi, S Cazzamalli, ... Chemical Science 14 (43), 12026-12033, 2023 | 1 | 2023 |
DNA-encoded affinity maturation libraries enable the discovery of low picomolar fibroblast activation protein inhibitors suitable for radioligand therapy of solid tumors S Puglioli, L Prati, S Oehler, A Galbiati, D Neri, S Cazzamalli, G Bassi, ... Cancer Research 83 (7_Supplement), 1989-1989, 2023 | | 2023 |
Industrial PhD: My way to go? S Puglioli Chem 9 (2), 255-257, 2023 | | 2023 |