Progesterone attenuates microglial-driven retinal degeneration and stimulates protective fractalkine-CX3CR1 signaling SL Roche, AC Wyse-Jackson, V Gomez-Vicente, P Lax, AM Ruiz-Lopez, ... PloS one 11 (11), e0165197, 2016 | 60 | 2016 |
Progesterone receptor signalling in retinal photoreceptor neuroprotection AC Wyse Jackson, SL Roche, AM Byrne, AM Ruiz‐Lopez, TG Cotter Journal of neurochemistry 136 (1), 63-77, 2015 | 51 | 2015 |
Alterations to retinal architecture prior to photoreceptor loss in a mouse model of retinitis pigmentosa SL Roche, AC Wyse-Jackson, AM Byrne, AM Ruiz-Lopez, TG Cotter Int. J. Dev. Biol 60 (4-6), 127-39, 2016 | 38 | 2016 |
Fractalkine-CX3CR1 signaling is critical for progesterone-mediated neuroprotection in the retina SL Roche, AC Wyse-Jackson, AM Ruiz-Lopez, AM Byrne, TG Cotter Scientific reports 7 (1), 43067, 2017 | 35 | 2017 |
The synthetic progesterone N orgestrel is neuroprotective in stressed photoreceptor‐like cells and retinal explants, mediating its effects via basic fibroblast growth factor … AC Wyse Jackson, TG Cotter European Journal of Neuroscience 43 (7), 899-911, 2016 | 27 | 2016 |
The synthetic progestin norgestrel modulates Nrf2 signaling and acts as an antioxidant in a model of retinal degeneration AM Byrne, AM Ruiz-Lopez, SL Roche, JN Moloney, AC Wyse-Jackson, ... Redox biology 10, 128-139, 2016 | 26 | 2016 |
The synthetic progestin norgestrel acts to increase LIF levels in the rd10 mouse model of retinitis pigmentosa AM Byrne, SL Roche, AM Ruiz-Lopez, ACW Jackson, TG Cotter Molecular vision 22, 264, 2016 | 24 | 2016 |
Pro‐survival redox signalling in progesterone‐mediated retinal neuroprotection AM Ruiz López, SL Roche, AC Wyse Jackson, JN Moloney, AM Byrne, ... European Journal of Neuroscience 46 (1), 1663-1672, 2017 | 19 | 2017 |
Progesterone analogue protects stressed photoreceptors via bFGF‐mediated calcium influx AC Wyse‐Jackson, SL Roche, AM Ruiz‐Lopez, JN Moloney, AM Byrne, ... European Journal of Neuroscience 44 (12), 3067-3079, 2016 | 17 | 2016 |
CX3CL1 action on microglia protects from diet-induced obesity by restoring POMC neuronal excitability and melanocortin system activity impaired by high-fat diet feeding J Banerjee, MD Dorfman, R Fasnacht, JD Douglass, AC Wyse-Jackson, ... International Journal of Molecular Sciences 23 (12), 6380, 2022 | 11 | 2022 |
Obesity-associated microglial inflammatory activation paradoxically improves glucose tolerance JD Douglass, KM Ness, M Valdearcos, A Wyse-Jackson, MD Dorfman, ... Cell Metabolism 35 (9), 1613-1629. e8, 2023 | 4 | 2023 |
Microglial inflammatory activation paradoxically improves glucose tolerance during diet-induced obesity JD Douglass, M Valdearcos, KM Ness, A Wyse-Jackson, MD Dorfman, ... Biorxiv, 2022.04. 19.488819, 2022 | 1 | 2022 |
Beyond Anti-inflammation: Steroid-induced Neuroprotection in the Retina AC Wyse-Jackson, G Groeger, TG Cotter | | 2018 |
Selective manipulation of microglia by chemogenetics: Implications for energy homeostasis and obesity pathogenesis AC Wyse-Jackson, MD Dorfman, JP Thaler GLIA 65, E483-E484, 2017 | | 2017 |
Breaking Bad: the role of microglia in retinal degeneration and neuroprotection S Roche, A Wyse-Jackson, T Cotter GLIA 65, E168-E169, 2017 | | 2017 |
Progesterone analogue protects stressed photoreceptors via bFGF AC Wyse-Jackson, SL Roche, AM Ruiz-Lopez, JN Moloney, AM Byrne, ... | | 2016 |
The role of microglia-photoreceptor crosstalk in retinal cell protection ACW Jackson, SL Roche, TG Cotter Investigative Ophthalmology & Visual Science 57 (12), 1192-1192, 2016 | | 2016 |
Steroid induced neuroprotection of damaged photoreceptor cells AC Wyse-Jackson University College Cork, 2016 | | 2016 |
Substantial modifications to retinal architecture occur prior to photoreceptor cell loss in the rd10 mouse model of retinitis pigmentosa SL ROCHE, AC WYSE-JACKSON, AM BYRNE, A RUIZ-LOPEZ, ... | | |