Binding kinetics of cariprazine and aripiprazole at the dopamine D3 receptor A Frank, DJ Kiss, GM Keserű, H Stark Scientific Reports 8 (1), 12509, 2018 | 37 | 2018 |
Experimental models for the discovery of novel anticonvulsant drugs: focus on pentylenetetrazole-induced seizures and associated memory deficits A Alachkar, SK Ojha, A Sadeq, A Adem, A Frank, H Stark, B Sadek Current pharmaceutical design 26 (15), 1693-1711, 2020 | 36 | 2020 |
Studies on anticonvulsant effects of novel histamine H3R antagonists in electrically and chemically induced seizures in rats A Alachkar, D Łażewska, G Latacz, A Frank, A Siwek, A Lubelska, ... International journal of molecular sciences 19 (11), 3386, 2018 | 25 | 2018 |
From medicinal plant extracts to defined chemical compounds targeting the histamine H4 receptor: Curcuma longa in the treatment of inflammation A Frank, S Abu-Lafi, A Adawi, JS Schwed, H Stark, A Rayan Inflammation Research 66, 923-929, 2017 | 25 | 2017 |
The Multi-Targeting Ligand ST-2223 with Histamine H3 Receptor and Dopamine D2/D3 Receptor Antagonist Properties Mitigates Autism-Like Repetitive … N Eissa, K Venkatachalam, P Jayaprakash, M Falkenstein, M Dubiel, ... International journal of molecular sciences 22 (4), 1947, 2021 | 21 | 2021 |
Nature-inspired pyrrolo [2, 3-d] pyrimidines targeting the histamine H3 receptor A Frank, F Meza-Arriagada, CO Salas, C Espinosa-Bustos, H Stark Bioorganic & Medicinal Chemistry 27 (14), 3194-3200, 2019 | 16 | 2019 |
Novel meriolin derivatives as rapid apoptosis inducers D Drießen, F Stuhldreier, A Frank, H Stark, S Wesselborg, B Stork, ... Bioorganic & Medicinal Chemistry 27 (15), 3463-3468, 2019 | 15 | 2019 |
Dual Target Ligands with 4-tert-Butylphenoxy Scaffold as Histamine H3 Receptor Antagonists and Monoamine Oxidase B Inhibitors D Łażewska, A Olejarz-Maciej, D Reiner, M Kaleta, G Latacz, M Zygmunt, ... International journal of molecular sciences 21 (10), 3411, 2020 | 14 | 2020 |
Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer’s disease J Godyń, P Zaręba, D Łażewska, D Stary, D Reiner-Link, A Frank, ... Bioorganic Chemistry 114, 105129, 2021 | 11 | 2021 |
Guanidine Derivatives: How Simple Structural Modification of Histamine H3R Antagonists Has Led to the Discovery of Potent Muscarinic M2R/M4R Antagonists M Staszewski, D Nelic, J Jończyk, M Dubiel, A Frank, H Stark, M Bajda, ... ACS Chemical Neuroscience 12 (13), 2503-2519, 2021 | 10 | 2021 |
Synthesis, in silico, and in vitro studies of novel dopamine D2 and D3 receptor ligands M Elek, N Djokovic, A Frank, S Oljacic, A Zivkovic, K Nikolic, H Stark Archiv der Pharmazie 354 (6), 2000486, 2021 | 10 | 2021 |
Talipexole variations as novel bitopic dopamine D 2 and D 3 receptor ligands L Stank, A Frank, S Hagenow, H Stark MedChemComm 10 (11), 1926-1929, 2019 | 6 | 2019 |
Sequentially catalyzed three-component Masuda–Suzuki–Sonogashira synthesis of fluorescent 2-Alkynyl-4-(7-azaindol-3-yl) pyrimidines: Three palladium-catalyzed processes in a … D Drießen, L Biesen, TJJ Müller Synlett 32 (05), 491-496, 2021 | 5 | 2021 |
Benzophenone Derivatives with Histamine H3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of … J Godyń, P Zaręba, D Stary, M Kaleta, KJ Kuder, G Latacz, S Mogilski, ... Molecules 28 (1), 238, 2022 | 3 | 2022 |
Biphenylalkoxyamine Derivatives–Histamine H3 Receptor Ligands with Butyrylcholinesterase Inhibitory Activity D Łażewska, P Zaręba, J Godyń, A Doroz-Płonka, A Frank, D Reiner-Link, ... Molecules 26 (12), 3580, 2021 | 3 | 2021 |
Prior activation of 5-HT7 receptors modulates the conditioned place preference with methylphenidate C Carbone, SLM Lo Russo, E Lacivita, A Frank, E Alleva, H Stark, L Saso, ... Frontiers in Behavioral Neuroscience 13, 208, 2019 | 3 | 2019 |
New lead elements for histamine H3 receptor ligands in the pyrrolo [2, 3-d] pyrimidine class C Espinosa-Bustos, A Frank, S Arancibia-Opazo, CO Salas, A Fierro, ... Bioorganic & Medicinal Chemistry Letters 28 (17), 2890-2893, 2018 | 3 | 2018 |
Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine‐Independent and Chronic Itch A Balzulat, WF Zhu, C Flauaus, V Hernandez‐Olmos, J Heering, ... Advanced Science, 2307237, 2024 | | 2024 |
Discovery of a new activator of Slack potassium channels with robust efficacy in models of histamine-independent and chronic itch A Balzulat, WF Zhu, C Flauaus, V Hernandez-Olmos, J Heering, ... bioRxiv, 2023.10. 05.560997, 2023 | | 2023 |
Dual Targeting Ligands—Histamine H3 Receptor Ligands with Monoamine Oxidase B Inhibitory Activity—In Vitro and In Vivo Evaluation D Łażewska, A Siwek, A Olejarz-Maciej, A Doroz-Płonka, ... Pharmaceutics 14 (10), 2187, 2022 | | 2022 |