Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array B Zetsche, M Heidenreich, P Mohanraju, I Fedorova, J Kneppers, ... Nature biotechnology 35 (1), 31-34, 2017 | 930 | 2017 |
Genome editing by natural and engineered CRISPR-associated nucleases WY Wu, JHG Lebbink, R Kanaar, N Geijsen, J Van Der Oost Nature chemical biology 14 (7), 642-651, 2018 | 116 | 2018 |
Good guide, bad guide: spacer sequence-dependent cleavage efficiency of Cas12a SCA Creutzburg, WY Wu, P Mohanraju, T Swartjes, F Alkan, J Gorodkin, ... Nucleic acids research 48 (6), 3228-3243, 2020 | 73 | 2020 |
The miniature CRISPR-Cas12m effector binds DNA to block transcription WY Wu, P Mohanraju, C Liao, B Adiego-Pérez, SCA Creutzburg, ... Molecular Cell 82 (23), 4487-4502. e7, 2022 | 36 | 2022 |
Cryo-EM structure of the transposon-associated TnpB enzyme R Nakagawa, H Hirano, SN Omura, S Nety, S Kannan, H Altae-Tran, ... Nature 616 (7956), 390-397, 2023 | 31 | 2023 |
Erratum: Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array B Zetsche, M Heidenreich, P Mohanraju, I Fedorova, J Kneppers, ... Nature Biotechnology 35 (2), 178-178, 2017 | 21 | 2017 |
Mechanistic and evolutionary insights into a type VM CRISPR–Cas effector enzyme SN Omura, R Nakagawa, C Südfeld, R Villegas Warren, WY Wu, H Hirano, ... Nature Structural & Molecular Biology 30 (8), 1172-1182, 2023 | 6 | 2023 |
Live-cell imaging reveals the trade-off between target search flexibility and efficiency for Cas9 and Cas12a L Olivi, C Bagchus, V Pool, E Bekkering, K Speckner, H Offerhaus, WY Wu, ... Nucleic acids research 52 (9), 5241-5256, 2024 | 1 | 2024 |
Crispr-associated based-editing of the complementary strand J Van Der Oost, WY Wu, RV WARREN US Patent App. 18/273,501, 2024 | | 2024 |
Cas12a nickases J Van Der Oost, RV Warren, MJ Luteijn, RHJ Staals, WY Wu, ... US Patent App. 18/176,874, 2023 | | 2023 |
Crispr type v-u1 system from mycobacterium mucogenicum and uses thereof J Van Der Oost, P Mohanraju, WY Wu, S Creutzburg US Patent App. 17/624,439, 2022 | | 2022 |
Adaptation by Type VA and VB CRISPR-Cas Systems Demonstrates Conserved Protospacer Selection Mechanisms Between Diverse CRISPR-Cas Types WY Wu, SA Jackson, C Almendros, AC Haagsma, S Yilmaz, G Gort, ... The CRISPR Journal 5 (4), 536-547, 2022 | | 2022 |
Right tool for the right job: Exploring the diversity of type V CRISPR-Cas systems WY Wu PQDT-Global, 2021 | | 2021 |