| Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC‐1 K Baar, AR Wende, TE Jones, M Marison, LA Nolte, MAY Chen, DP Kelly, ... The FASEB journal 16 (14), 1879-1886, 2002 | 1304 | 2002 |
| PGC-1α deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis TC Leone, JJ Lehman, BN Finck, PJ Schaeffer, AR Wende, S Boudina, ... PLoS biology 3 (4), e101, 2005 | 1129 | 2005 |
| PGC-1α coactivates PDK4 gene expression via the orphan nuclear receptor ERRα: a mechanism for transcriptional control of muscle glucose metabolism AR Wende, JM Huss, PJ Schaeffer, V Giguere, DP Kelly Molecular and cellular biology 25 (24), 10684-10694, 2005 | 428 | 2005 |
| Lipotoxicity in the heart AR Wende, ED Abel Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2010 | 376 | 2010 |
| A role for the transcriptional coactivator PGC-1α in muscle refueling AR Wende, PJ Schaeffer, GJ Parker, C Zechner, DH Han, MM Chen, ... Journal of Biological Chemistry 282 (50), 36642-36651, 2007 | 321 | 2007 |
| Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy J Kim, AR Wende, S Sena, HA Theobald, J Soto, C Sloan, BE Wayment, ... Molecular endocrinology 22 (11), 2531-2543, 2008 | 243 | 2008 |
| Cardiac energy metabolism in heart failure GD Lopaschuk, QG Karwi, R Tian, AR Wende, ED Abel Circulation research 128 (10), 1487-1513, 2021 | 226 | 2021 |
| Mitochondrial reactive oxygen species in lipotoxic hearts induce post-translational modifications of AKAP121, DRP1, and OPA1 that promote mitochondrial fission K Tsushima, H Bugger, AR Wende, J Soto, GA Jenson, AR Tor, ... Circulation research 122 (1), 58-73, 2018 | 190 | 2018 |
| Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha NH Banke, AR Wende, TC Leone, JM O'donnell, ED Abel, DP Kelly, ... Circulation research 107 (2), 233-241, 2010 | 171 | 2010 |
| Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart ME Young, RA Brewer, RA Peliciari-Garcia, HE Collins, L He, TL Birky, ... Journal of biological rhythms 29 (4), 257-276, 2014 | 163 | 2014 |
| A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy BT O'Neill, J Kim, AR Wende, HA Theobald, J Tuinei, J Buchanan, A Guo, ... Cell metabolism 6 (4), 294-306, 2007 | 153 | 2007 |
| PGC-1β deficiency accelerates the transition to heart failure in pressure overload hypertrophy C Riehle, AR Wende, VG Zaha, KM Pires, B Wayment, C Olsen, H Bugger, ... Circulation research 109 (7), 783-793, 2011 | 152 | 2011 |
| Metabolic origins of heart failure AR Wende, MK Brahma, GR McGinnis, ME Young Basic to Translational Science 2 (3), 297-310, 2017 | 143 | 2017 |
| Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α)-deficient mice SC Burgess, TC Leone, AR Wende, MA Croce, Z Chen, AD Sherry, ... Journal of Biological Chemistry 281 (28), 19000-19008, 2006 | 131 | 2006 |
| Intramuscular fat and inflammation differ in older adults: the impact of frailty and inactivity O Addison, MJ Drummond, PC LaStayo, LE Dibble, AR Wende, ... The journal of nutrition, health & aging 18, 532-538, 2014 | 129 | 2014 |
| Mechanisms of lipotoxicity in the cardiovascular system AR Wende, JD Symons, ED Abel Current hypertension reports 14, 517-531, 2012 | 129 | 2012 |
| Insulin receptor substrate signaling suppresses neonatal autophagy in the heart C Riehle, AR Wende, S Sena, KM Pires, RO Pereira, Y Zhu, H Bugger, ... The Journal of clinical investigation 123 (12), 5319-5333, 2013 | 118 | 2013 |
| Calcineurin and calcium/calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscle PJ Schaeffer, AR Wende, CJ Magee, JR Neilson, TC Leone, F Chen, ... Journal of Biological Chemistry 279 (38), 39593-39603, 2004 | 104 | 2004 |
| Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training C Riehle, AR Wende, Y Zhu, KJ Oliveira, RO Pereira, BP Jaishy, J Bevins, ... Molecular and cellular biology 34 (18), 3450-3460, 2014 | 96 | 2014 |
| Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of … AR Wende, BT O'Neill, H Bugger, C Riehle, J Tuinei, J Buchanan, ... Molecular and cellular biology 35 (5), 831-846, 2015 | 93 | 2015 |
Evan Dale AbelUniversity of Iowa, Carver College of MedicineVerified email at uiowa.edu
