Adam R. Wende, PhD, FAHA
Adam R. Wende, PhD, FAHA
Associate Professor of Pathology, University of Alabama at Birmingham
Verified email at - Homepage
Cited by
Cited by
Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC‐1
K Baar, AR Wende, TE Jones, M Marison, LA Nolte, MAY Chen, DP Kelly, ...
The FASEB journal 16 (14), 1879-1886, 2002
PGC-1α deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis
TC Leone, JJ Lehman, BN Finck, PJ Schaeffer, AR Wende, S Boudina, ...
PLoS biology 3 (4), e101, 2005
PGC-1α coactivates PDK4 gene expression via the orphan nuclear receptor ERRα: a mechanism for transcriptional control of muscle glucose metabolism
AR Wende, JM Huss, PJ Schaeffer, V Giguere, DP Kelly
Molecular and cellular biology 25 (24), 10684-10694, 2005
Lipotoxicity in the heart
AR Wende, ED Abel
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2010
A role for the transcriptional coactivator PGC-1α in muscle refueling
AR Wende, PJ Schaeffer, GJ Parker, C Zechner, DH Han, MM Chen, ...
Journal of Biological Chemistry 282 (50), 36642-36651, 2007
Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy
J Kim, AR Wende, S Sena, HA Theobald, J Soto, C Sloan, BE Wayment, ...
Molecular endocrinology 22 (11), 2531-2543, 2008
Cardiac energy metabolism in heart failure
GD Lopaschuk, QG Karwi, R Tian, AR Wende, ED Abel
Circulation research 128 (10), 1487-1513, 2021
Mitochondrial reactive oxygen species in lipotoxic hearts induce post-translational modifications of AKAP121, DRP1, and OPA1 that promote mitochondrial fission
K Tsushima, H Bugger, AR Wende, J Soto, GA Jenson, AR Tor, ...
Circulation research 122 (1), 58-73, 2018
Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARalpha
NH Banke, AR Wende, TC Leone, JM O'donnell, ED Abel, DP Kelly, ...
Circulation research 107 (2), 233-241, 2010
Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart
ME Young, RA Brewer, RA Peliciari-Garcia, HE Collins, L He, TL Birky, ...
Journal of biological rhythms 29 (4), 257-276, 2014
A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy
BT O'Neill, J Kim, AR Wende, HA Theobald, J Tuinei, J Buchanan, A Guo, ...
Cell metabolism 6 (4), 294-306, 2007
PGC-1β deficiency accelerates the transition to heart failure in pressure overload hypertrophy
C Riehle, AR Wende, VG Zaha, KM Pires, B Wayment, C Olsen, H Bugger, ...
Circulation research 109 (7), 783-793, 2011
Metabolic origins of heart failure
AR Wende, MK Brahma, GR McGinnis, ME Young
Basic to Translational Science 2 (3), 297-310, 2017
Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α)-deficient mice
SC Burgess, TC Leone, AR Wende, MA Croce, Z Chen, AD Sherry, ...
Journal of Biological Chemistry 281 (28), 19000-19008, 2006
Intramuscular fat and inflammation differ in older adults: the impact of frailty and inactivity
O Addison, MJ Drummond, PC LaStayo, LE Dibble, AR Wende, ...
The journal of nutrition, health & aging 18, 532-538, 2014
Mechanisms of lipotoxicity in the cardiovascular system
AR Wende, JD Symons, ED Abel
Current hypertension reports 14, 517-531, 2012
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart
C Riehle, AR Wende, S Sena, KM Pires, RO Pereira, Y Zhu, H Bugger, ...
The Journal of clinical investigation 123 (12), 5319-5333, 2013
Calcineurin and calcium/calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscle
PJ Schaeffer, AR Wende, CJ Magee, JR Neilson, TC Leone, F Chen, ...
Journal of Biological Chemistry 279 (38), 39593-39603, 2004
Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training
C Riehle, AR Wende, Y Zhu, KJ Oliveira, RO Pereira, BP Jaishy, J Bevins, ...
Molecular and cellular biology 34 (18), 3450-3460, 2014
Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of …
AR Wende, BT O'Neill, H Bugger, C Riehle, J Tuinei, J Buchanan, ...
Molecular and cellular biology 35 (5), 831-846, 2015
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