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Migara Jayasinghe (Jay)
Migara Jayasinghe (Jay)
Postdoctoral Fellow, Cancer Science Institute of Singapore
Verified email at u.nus.edu
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Cited by
Cited by
Year
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
JA Welsh, DCI Goberdhan, L O'Driscoll, EI Buzas, C Blenkiron, ...
Journal of extracellular vesicles 13 (2), e12404, 2024
1492024
Covalent conjugation of extracellular vesicles with peptides and nanobodies for targeted therapeutic delivery
TC Pham, MK Jayasinghe, TT Pham, Y Yang, L Wei, WM Usman, H Chen, ...
Journal of Extracellular Vesicles 10 (4), e12057, 2021
1152021
Extracellular Vesicles as an Efficient and Versatile System for Drug Delivery
XTT Dang, JM Kavishka, DX Zhang, M Pirisinu, MTN Le
Cells 9 (10), 2191, 2020
922020
Robust delivery of RIG‐I agonists using extracellular vesicles for anti‐cancer immunotherapy
B Peng, TM Nguyen, MK Jayasinghe, C Gao, TT Pham, LT Vu, EYM Yeo, ...
Journal of Extracellular Vesicles 11 (4), e12187, 2022
412022
Advances in Drug Delivery Systems Based on Red Blood Cells and Their Membrane-Derived Nanoparticles
PHD Nguyen, MK Jayasinghe, AH Le, B Peng, MTN Le
ACS nano 17 (6), 5187-5210, 2023
342023
New approaches in extracellular vesicle engineering for improving the efficacy of anti-cancer therapies
MK Jayasinghe, M Tan, B Peng, Y Yang, G Sethi, M Pirisinu, MTN Le
Seminars in Cancer Biology 74, 62-78, 2021
342021
Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy
MK Jayasinghe, M Pirisinu, Y Yang, B Peng, TT Pham, CY Lee, M Tan, ...
Theranostics 12 (7), 3288, 2022
262022
The role of in silico research in developing nanoparticle-based therapeutics
MK Jayasinghe, LC Yu, TTT Tran, R Tan, S Chew, BYZ Jie, WX Loh, ...
Frontiers in Digital Health, 35, 2022
112022
Extracellular vesicles and lipoproteins–Smart messengers of blood cells in the circulation
PHD Nguyen, AH Le, JSQ Pek, TT Pham, MK Jayasinghe, DV Do, ...
Journal of Extracellular Biology 1 (7), e49, 2022
92022
Endosomal escape of nucleic acids from extracellular vesicles mediates functional therapeutic delivery
TT Pham, H Chen, PHD Nguyen, MK Jayasinghe, AH Le, MTN Le
Pharmacological Research 188, 106665, 2023
82023
FAM3C in circulating tumor-derived extracellular vesicles promotes non-small cell lung cancer growth in secondary sites
WL Thuya, LR Kong, NL Syn, LW Ding, ESH Cheow, RTX Wong, T Wang, ...
Theranostics 13 (2), 621, 2023
82023
Targeted intragenic demethylation initiates chromatin rewiring for gene activation
YV Liu, MA Bassal, MK Jayasinghe, QXX Lin, CS Wu, JP Tang, J Kwon, ...
BioRxiv, 2020.07. 16.205922, 2020
82020
CD33‐targeting extracellular vesicles deliver antisense oligonucleotides against FLT3‐ITD and miR‐125b for specific treatment of acute myeloid leukaemia
H Chen, MK Jayasinghe, EYM Yeo, Z Wu, M Pirisinu, WM Usman, ...
Cell proliferation 55 (9), e13255, 2022
72022
Red blood cell extracellular vesicles deliver therapeutic siRNAs to skeletal muscles for treatment of cancer cachexia
B Peng, Y Yang, Z Wu, R Tan, TT Pham, EYM Yeo, M Pirisinu, ...
Molecular Therapy 31 (5), 1418-1436, 2023
52023
Red Blood Cell-Derived Extracellular Vesicles Display Endogenous Antiviral Effects and Enhance the Efficacy of Antiviral Oligonucleotide Therapy
MK Jayasinghe, C Gao, G Yap, BZJ Yeo, LT Vu, DJW Tay, WX Loh, ...
ACS nano 17 (21), 21639-21661, 2023
42023
Endocytosis of red blood cell extracellular vesicles by macrophages leads to cytoplasmic heme release and prevents foam cell formation in atherosclerosis
TT Pham, AH Le, CP Dang, SY Chong, DV Do, B Peng, MK Jayasinghe, ...
Journal of Extracellular Vesicles 12 (8), 12354, 2023
42023
Harnessing Extracellular Vesicles from Red Blood Cells for Targeted Delivery of Therapeutic Peptides and RNAs for Leukemia Treatment
MK Jayasinghe, M Pirisinu, H Chen, Y Yang, B Peng, J Shi, MTN Le
Blood 138 (Supplement 1), 3980-3980, 2021
32021
Surface modified extracellular vesicles
J Shi, TNM Le, L Wei, CT Pham, WM Usman, MK Jayasinghe
US Patent App. 17/278,280, 2021
12021
Abstract LT08: Extracellular Vesicle Surface Display Enhances the Therapeutic Efficacy and Safety Profile of Cancer Immunotherapy
MK Jayasinghe, DLX Tian, YS Lay, CY Lee, BZJ Yeo, D Van Hoang, ...
Cancer Research 84 (8_Supplement), LT08-LT08, 2024
2024
Surface Modified Red Blood Cells And Methods Of Generating The Same
TNM Le, MK Jayasinghe, P Boya, J Shi
US Patent App. 18/274,649, 2024
2024
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