A tethering complex drives the terminal stage of SNARE-dependent membrane fusion M D’Agostino, HJ Risselada, A Lürick, C Ungermann, A Mayer Nature 551 (7682), 634-638, 2017 | 103 | 2017 |
The cytosolic chaperone α-crystallin B rescues folding and compartmentalization of misfolded multispan transmembrane proteins M D'Agostino, V Lemma, G Chesi, M Stornaiuolo, M Cannata Serio, ... Journal of cell science 126 (18), 4160-4172, 2013 | 43 | 2013 |
SNARE‐mediated membrane fusion arrests at pore expansion to regulate the volume of an organelle M D'Agostino, HJ Risselada, LJ Endter, V Comte‐Miserez, A Mayer The EMBO journal 37 (19), e99193, 2018 | 38 | 2018 |
Ligand of Numb proteins LNX1p80 and LNX2 interact with the human glycoprotein CD8α and promote its ubiquitylation and endocytosis M D'Agostino, G Tornillo, MG Caporaso, MV Barone, E Ghigo, S Bonatti, ... Journal of cell science 124 (21), 3545-3556, 2011 | 37 | 2011 |
Differential phosphorylation-based regulation of αB-crystallin chaperone activity for multipass transmembrane proteins M Ciano, S Allocca, MC Ciardulli, L Della Volpe, S Bonatti, M D'Agostino Biochemical and biophysical research communications 479 (2), 325-330, 2016 | 35 | 2016 |
Unconventional secretion of α-Crystallin B requires the Autophagic pathway and is controlled by phosphorylation of its serine 59 residue M D’Agostino, G Scerra, M Cannata Serio, MG Caporaso, S Bonatti, ... Scientific Reports 9 (1), 16892, 2019 | 24 | 2019 |
Effects of long-term citrate treatment in the PC3 prostate cancer cell line C Caiazza, M D’Agostino, F Passaro, D Faicchia, M Mallardo, S Paladino, ... International Journal of Molecular Sciences 20 (11), 2613, 2019 | 23 | 2019 |
Steric hindrance of SNARE transmembrane domain organization impairs the hemifusion‐to‐fusion transition M D'Agostino, HJ Risselada, A Mayer EMBO reports 17 (11), 1590-1608, 2016 | 22 | 2016 |
A disorder-to-order structural transition in the COOH-tail of Fz4 determines misfolding of the L501fsX533-Fz4 mutant V Lemma, M D'Agostino, MG Caporaso, M Mallardo, G Oliviero, ... Scientific Reports 3 (1), 2659, 2013 | 21 | 2013 |
Lysosomal positioning diseases: beyond substrate storage G Scerra, V De Pasquale, M Scarcella, MG Caporaso, LM Pavone, ... Open biology 12 (10), 220155, 2022 | 17 | 2022 |
Metabolites profiling of melanoma interstitial fluids reveals uridine diphosphate as potent immune modulator capable of limiting tumor growth E Vecchio, C Caiazza, S Mimmi, A Avagliano, E Iaccino, T Brusco, ... Frontiers in Cell and Developmental Biology 9, 730726, 2021 | 17 | 2021 |
Familial Exudative Vitreoretinopathy caused by a Homozygous Mutation in TSPAN12 in a Cystic Fibrosis Infant M Savarese, E Spinelli, F Gandolfo, V Lemma, G Di Fruscio, R Padoan, ... Ophthalmic Genetics 35 (3), 184-186, 2014 | 16 | 2014 |
PD-L1 expression fluctuates concurrently with cyclin D in glioblastoma cells M Tufano, P D’Arrigo, M D’Agostino, C Giordano, L Marrone, E Cesaro, ... Cells 10 (9), 2366, 2021 | 15 | 2021 |
ER reorganization is remarkably induced in COS-7 cells accumulating transmembrane protein receptors not competent for export from the endoplasmic reticulum M D’Agostino, A Crespi, E Polishchuk, S Generoso, G Martire, ... The Journal of Membrane Biology 247, 1149-1159, 2014 | 15 | 2014 |
Early onset effects of single substrate accumulation recapitulate major features of LSD in patient-derived lysosomes G Scerra, V De Pasquale, LM Pavone, MG Caporaso, A Mayer, M Renna, ... Iscience 24 (7), 2021 | 13 | 2021 |
Competitive binding of extracellular accumulated heparan sulfate reduces lysosomal storage defects and triggers neuronal differentiation in a model of Mucopolysaccharidosis IIIB V De Pasquale, G Scerra, M Scarcella, M D'Agostino, LM Pavone Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1868 (11), 119113, 2021 | 9 | 2021 |
An αB-crystallin peptide rescues compartmentalization and trafficking response to Cu overload of ATP7B-H1069Q, the most frequent cause of Wilson disease in the Caucasian population S Allocca, M Ciano, MC Ciardulli, C D’Ambrosio, A Scaloni, D Sarnataro, ... International Journal of Molecular Sciences 19 (7), 1892, 2018 | 9 | 2018 |
The HSPB1-p62/SQSTM1 functional complex regulates the unconventional secretion and transcellular spreading of the HD-associated mutant huntingtin protein R Bonavita, G Scerra, R Di Martino, S Nuzzo, E Polishchuk, M Di Gennaro, ... Human Molecular Genetics 32 (14), 2269-2291, 2023 | 8 | 2023 |
N-Substituted l-Iminosugars for the Treatment of Sanfilippo Type B Syndrome V De Pasquale, A Esposito, G Scerra, M Scarcella, M Ciampa, A Luongo, ... Journal of Medicinal Chemistry 66 (3), 1790-1808, 2023 | 7 | 2023 |
Protocol for labeling and fixation of intact lysosomes with esterified amino acid analogs to assess lysosomal expansion in living eukaryotic cells G Scerra, MG Caporaso, M Renna, M D’Agostino STAR protocols 2 (4), 100916, 2021 | 7 | 2021 |