The National Cancer Institute ALMANAC: a comprehensive screening resource for the detection of anticancer drug pairs with enhanced therapeutic activity SL Holbeck, R Camalier, JA Crowell, JP Govindharajulu, M Hollingshead, ... Cancer research 77 (13), 3564-3576, 2017 | 279 | 2017 |
Chitosan-recombinamer layer-by-layer coatings for multifunctional implants JP Govindharajulu, X Chen, Y Li, JC Rodriguez-Cabello, M Battacharya, ... International Journal of Molecular Sciences 18 (2), 369, 2017 | 68 | 2017 |
Effect of a Smac mimetic (TL32711, Birinapant) on the apoptotic program and apoptosis biomarkers examined with validated multiplex immunoassays fit for clinical use AK Srivastava, S Jaganathan, L Stephen, MG Hollingshead, A Layhee, ... Clinical Cancer Research 22 (4), 1000-1010, 2016 | 28 | 2016 |
Molecular pharmacodynamics-guided scheduling of biologically effective doses: a drug development paradigm applied to MET tyrosine kinase inhibitors AK Srivastava, MG Hollingshead, JP Govindharajulu, JM Covey, D Liston, ... Molecular cancer therapeutics 17 (3), 698-709, 2018 | 12 | 2018 |
Comparative oncology assessment of a novel inhibitor of valosin-containing protein in tumor-bearing dogs AK LeBlanc, CN Mazcko, TM Fan, DM Vail, BK Flesner, JN Bryan, S Li, ... Molecular cancer therapeutics 21 (10), 1510-1523, 2022 | 5 | 2022 |
Pazopanib to suppress MET signaling in patients with refractory advanced solid tumors. AK Srivastava, JP Govindharajulu, SR Park, T Navas, KV Ferry-Galow, ... American Society of Clinical Oncology (ASCO) Annual Meeting, 2016 | 4 | 2016 |
Pharmacodynamics of first-in-class p97 inhibitors that disrupt protein homeostasis in cancer. AK Srivastava, JP Govindharajulu, MG Hollingshead, H Stotler, F Wang, ... Journal of Clinical Oncology 36 (15_suppl), e14539-e14539, 2018 | 2 | 2018 |
Met target inhibition-guided efficacy in preclinical models AK Srivastava, M Hollingshead, JP Govindharajulu, JM Covey, D Liston, ... Cancer Res 74, 2014 | 2 | 2014 |
Measuring phospho-MET by multiplex immunofluorescence to aid in selection of patients with MET activation in tumors T Navas, AK Srivastava, JP Govindharajulu, YA Evrard, S Borgel, J Carter, ... J Clin Oncol 37, 2019 | 1 | 2019 |
BAX-BAK heterodimer as a pharmacodynamic biomarker of on-target drug action of Mcl-1 inhibitors to evaluate in-vivo effectiveness. AK Srivastava, JP Govindharajulu, MG Hollingshead, WJ Moore, ... Journal of Clinical Oncology 36 (15_suppl), 2582-2582, 2018 | 1 | 2018 |
Abstract CT120: Phase 1 trial of bortezomib and clofarabine combination in adults with refractory solid tumors AL De Souza, N Takebe, AP Chen, JH Doroshow, RE Parchment, ... Cancer Research 84 (7_Supplement), CT120-CT120, 2024 | | 2024 |
Novel multiplexed assays of ferroptosis, pyroptosis and necroptosis biomarkers for translational studies WG Herrick, J Govindharajulu, RE Parchment, JH Doroshow, ... Cancer Research 83 (7_Supplement), 6143-6143, 2023 | | 2023 |
Determinants of birinapant efficacy in triple negative breast cancer EA Brown, CH Yang, E Cortes-Sanchez, Z Chu, J Govindharajulu, ... Cancer Research 83 (7_Supplement), 393-393, 2023 | | 2023 |
Detection of bcl-2 family heterodimer complexes and use thereof AK Srivastava, D Esposito, JP Govindharajulu, RE Parchment, ... US Patent App. 17/422,972, 2022 | | 2022 |
Intra-tumoral pharmacodynamics of selumetinib in serial biopsies from patients with neurofibroma W Herrick, G O'Sullivan Coyne, A Gross, E Dombi, J Govindharajulu, ... Cancer Research 80 (16_Supplement), 805-805, 2020 | | 2020 |
Intratumoral levels of BAX-BAK heterodimer as a specific on-target pharmacodynamic biomarker of drug action by novel BH3 mimetics AK Srivastava, JP Govindharajulu, D Esposito, MG Hollingshead, ... Cancer Research 78 (13_Supplement), 4920-4920, 2018 | | 2018 |
Cryogenic biopsy device for preservation of labile biomarkers E Nevo, MG Hollingshead, K Ferry-Galow, JP Govindharajulu, S Nevo, ... Cancer Research 78 (13_Supplement), 4537-4537, 2018 | | 2018 |
Multiplex analysis of apoptosis pathway reveals pharmacodynamic biomarkers of novel drug combinations with unexpected additive/synergistic efficacy AK Srivastava, MG Hollingshead, J Govindharajulu, D Wilsker, A Chen, ... Cold Spring Harbor Laboratory Cell Death Meeting, 2015 | | 2015 |
Bioactive and Antimicrobial Layer-by-Layer Coatings on Titanium Surfaces JP Govindharajulu, Y Li, H Hirt, JC Rodriguez-Cabello, SU Gorr, ... IADR/AADR/CADR 91st General Session, 2013 | | 2013 |
Bioactive and Antimicrobial Layer-by-Layer Assembly on Titanium Surface JP Govindharajulu University of Minnesota, 2013 | | 2013 |