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Zachary A Bornholdt
Zachary A Bornholdt
Mapp Biopharmaceutical, Inc.
Verified email at mappbio.com
Title
Cited by
Cited by
Year
Structural rearrangement of ebola virus VP40 begets multiple functions in the virus life cycle
ZA Bornholdt, T Noda, DM Abelson, P Halfmann, MR Wood, Y Kawaoka, ...
Cell 154 (4), 763-774, 2013
2512013
Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak
ZA Bornholdt, HL Turner, CD Murin, W Li, D Sok, CA Souders, AE Piper, ...
Science 351 (6277), 1078-1083, 2016
2242016
Structures of protective antibodies reveal sites of vulnerability on Ebola virus
CD Murin, ML Fusco, ZA Bornholdt, X Qiu, GG Olinger, L Zeitlin, ...
Proceedings of the National Academy of Sciences 111 (48), 17182-17187, 2014
2162014
X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus
ZA Bornholdt, BVV Prasad
Nature 456 (7224), 985-988, 2008
2072008
X-ray structure of influenza virus NS1 effector domain
ZA Bornholdt, BVV Prasad
Nature structural & molecular biology 13 (6), 559-560, 2006
1802006
Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression
CR Kimberlin, ZA Bornholdt, S Li, VL Woods Jr, IJ MacRae, EO Saphire
Proceedings of the National Academy of Sciences 107 (1), 314-319, 2010
1582010
Mechanism of human antibody-mediated neutralization of Marburg virus
AI Flyak, PA Ilinykh, CD Murin, T Garron, X Shen, ML Fusco, T Hashiguchi, ...
Cell 160 (5), 893-903, 2015
1562015
The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold
APP Zhang, ZA Bornholdt, T Liu, DM Abelson, DE Lee, S Li, VL Woods Jr, ...
PLoS pathogens 8 (2), e1002550, 2012
1522012
Antibodies from a human survivor define sites of vulnerability for broad protection against ebolaviruses
AZ Wec, AS Herbert, CD Murin, EK Nyakatura, DM Abelson, JM Fels, ...
Cell 169 (5), 878-890. e15, 2017
1482017
Structural basis for Marburg virus neutralization by a cross-reactive human antibody
T Hashiguchi, ML Fusco, ZA Bornholdt, JE Lee, AI Flyak, R Matsuoka, ...
Cell 160 (5), 904-912, 2015
1332015
A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses
AZ Wec, EK Nyakatura, AS Herbert, KA Howell, FW Holtsberg, RR Bakken, ...
Science 354 (6310), 350-354, 2016
1252016
Host-primed Ebola virus GP exposes a hydrophobic NPC1 receptor-binding pocket, revealing a target for broadly neutralizing antibodies
ZA Bornholdt, E Ndungo, ML Fusco, S Bale, AI Flyak, JE Crowe Jr, ...
MBio 7 (1), 10.1128/mbio. 02154-15, 2016
1102016
The influenza A virus protein NS1 displays structural polymorphism
B Carrillo, JM Choi, ZA Bornholdt, B Sankaran, AP Rice, BVV Prasad
Journal of virology 88 (8), 4113-4122, 2014
992014
Development of a human antibody cocktail that deploys multiple functions to confer pan-ebolavirus protection
AZ Wec, ZA Bornholdt, S He, AS Herbert, E Goodwin, AS Wirchnianski, ...
Cell host & microbe 25 (1), 39-48. e5, 2019
952019
Crystal structure of the Nipah virus phosphoprotein tetramerization domain
JF Bruhn, KC Barnett, J Bibby, JMH Thomas, RM Keegan, DJ Rigden, ...
Journal of virology 88 (1), 758-762, 2014
892014
Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism
S Bale, JP Julien, ZA Bornholdt, CR Kimberlin, P Halfmann, ...
Public Library of Science 8 (9), e1002916, 2012
892012
A two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates
ZA Bornholdt, AS Herbert, CE Mire, S He, RW Cross, AZ Wec, ...
Cell host & microbe 25 (1), 49-58. e5, 2019
882019
Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine
AZ Wec, D Haslwanter, YN Abdiche, L Shehata, N Pedreņo-Lopez, ...
Proceedings of the National Academy of Sciences 117 (12), 6675-6685, 2020
812020
Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism
S Bale, JP Julien, ZA Bornholdt, AS Krois, IA Wilson, EO Saphire
Journal of virology 87 (18), 10385-10388, 2013
672013
The ebolavirus VP24 interferon antagonist: know your enemy
APP Zhang, DM Abelson, ZA Bornholdt, T Liu, VL Woods, Jr, EO Saphire
Virulence 3 (5), 440-445, 2012
482012
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