| Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications C Liu, L Zhang, H Liu, K Cheng Journal of controlled release 266, 17-26, 2017 | 509 | 2017 |
| One-pot preparation of magnetic N-heterocyclic carbene-functionalized silica nanoparticles for the Suzuki–Miyaura coupling of aryl chlorides: improved activity and facile … H Yang, Y Wang, Y Qin, Y Chong, Q Yang, G Li, L Zhang, W Li Green chemistry 13 (5), 1352-1361, 2011 | 121 | 2011 |
| Discovery of low-molecular weight anti-PD-L1 peptides for cancer immunotherapy H Liu, Z Zhao, L Zhang, Y Li, A Jain, A Barve, W Jin, Y Liu, J Fetse, ... Journal for immunotherapy of cancer 7, 1-14, 2019 | 91 | 2019 |
| Synthesis and biological evaluation of novel marine-derived indole-based 1, 2, 4-oxadiazoles derivatives as multifunctional neuroprotective agents CS Jiang, Y Fu, L Zhang, JX Gong, ZZ Wang, W Xiao, HY Zhang, YW Guo Bioorganic & Medicinal Chemistry Letters 25 (2), 216-220, 2015 | 83 | 2015 |
| Pedunculoside, a novel triterpene saponin extracted from Ilex rotunda, ameliorates high-fat diet induced hyperlipidemia in rats C Liu, YJ Shen, QB Tu, YR Zhao, H Guo, J Wang, L Zhang, HW Shi, Y Sun Biomedicine & Pharmacotherapy 101, 608-616, 2018 | 51 | 2018 |
| Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity L Zhang, CS Jiang, LX Gao, JX Gong, ZH Wang, JY Li, J Li, XW Li, ... Bioorganic & Medicinal Chemistry Letters 26 (3), 778-781, 2016 | 50 | 2016 |
| Discovery of aptamer ligands for hepatic stellate cells using SELEX Z Chen, H Liu, A Jain, L Zhang, C Liu, K Cheng Theranostics 7 (12), 2982, 2017 | 37 | 2017 |
| A periodic mesoporous hybrid material with a built-in palladium complex: An efficient catalyst for the Suzuki coupling and alcohol oxidation H Yang, Z Ma, Y Qing, G Xie, J Gao, J Gao Applied Catalysis A: General 382 (2), 312-321, 2010 | 35 | 2010 |
| Immune checkpoint blockade in cancer immunotherapy: mechanisms, clinical outcomes, and safety profiles of PD-1/PD-L1 inhibitors Y Yan, L Zhang, Y Zuo, H Qian, C Liu Archivum Immunologiae et Therapiae Experimentalis 68 (6), 36, 2020 | 34 | 2020 |
| Ilexgenin A, a novel pentacyclic triterpenoid extracted from Aquifoliaceae shows reduction of LPS-induced peritonitis in mice W Sun, C Liu, Y Zhang, X Qiu, L Zhang, H Zhao, Y Rong, Y Sun European journal of pharmacology 797, 94-105, 2017 | 27 | 2017 |
| Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo X Ding, AC Sharko, MSJ McDermott, GP Schools, A Chumanevich, H Ji, ... Proceedings of the National Academy of Sciences 119 (32), e2201073119, 2022 | 17 | 2022 |
| A selective and orally bioavailable quinoline-6-carbonitrile-based inhibitor of CDK8/19 mediator kinase with tumor-enriched pharmacokinetics L Zhang, C Cheng, J Li, L Wang, AA Chumanevich, DC Porter, A Mindich, ... Journal of medicinal chemistry 65 (4), 3420-3433, 2022 | 16 | 2022 |
| CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins M Chen, J Li, L Zhang, L Wang, C Cheng, H Ji, S Altilia, X Ding, G Cai, ... Nucleic Acids Research 51 (14), 7288-7313, 2023 | 11 | 2023 |
| Efficient Total Synthesis of (S)‐Dihydroresorcylide, a Bioactive Twelve‐Membered Macrolide L Zhang, W Ma, L Xu, F Deng, Y Guo Chinese Journal of Chemistry 31 (3), 339-343, 2013 | 11 | 2013 |
| Concise synthesis and PTP1B inhibitory activity of (R)- and (S)-dihydroresorcylide CS Jiang, L Zhang, JX Gong, JY Li, LG Yao, J Li, YW Guo Journal of Asian natural products research 19 (12), 1204-1213, 2017 | 4 | 2017 |
| An Optimized method for construction of Epstein-Barr virus-transformed immortalized lymphoblastoid cell lines C Liu, H Liu, L Zhang, N Deng Journal of Medical Discovery 2 (1), 1-4, 2017 | 4 | 2017 |
| Quinoline-based compounds and methods of inhibiting CDK8/19 I Roninson, C McInnes, M Chen, L Zhang, J Li US Patent 11,014,906, 2021 | 2 | 2021 |
| CDK19 and CDK8 Mediator kinases drive androgen-independent in vivo growth of castration-resistant prostate cancer J Li, TA Hilimire, Y Liu, L Wang, J Liang, B Gyorffy, V Sikirzhytski, H Ji, ... bioRxiv, 2023.08. 08.552491, 2023 | 1 | 2023 |
| PROTAC degraders of CDK8/CDK19 Mediator kinases potently suppress multiple myeloma proliferation L Zhang, J Li, CE Dowling, EV Broude, IB Roninson, C McInnes, M Chen Cancer Research 83 (7_Supplement), 5018-5018, 2023 | | 2023 |
| Bicyclic pyridine compositions and methods of using the same for cancer therapy IB Roninson, M Chen, J Li, J Liang, L Zhang, C McInnes US Patent 11,572,369, 2023 | | 2023 |
