| DFMO and 5-azacytidine increase M1 macrophages in the tumor microenvironment of murine ovarian cancer M Travers, SM Brown, M Dunworth, CE Holbert, KR Wiehagen, ... Cancer research 79 (13), 3445-3454, 2019 | 71 | 2019 |
| Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy RC Geck, JR Foley, TM Stewart, JM Asara, RA Casero, A Toker Journal of Biological Chemistry 295 (19), 6263-6277, 2020 | 47 | 2020 |
| Polyamine homeostasis in Snyder-Robinson syndrome T Murray-Stewart, M Dunworth, JR Foley, CE Schwartz, RA Casero Jr Medical sciences 6 (4), 112, 2018 | 42 | 2018 |
| Autophagy induction by exogenous polyamines is an artifact of bovine serum amine oxidase activity in culture serum CE Holbert, M Dunworth, JR Foley, TT Dunston, TM Stewart, RA Casero Journal of Biological Chemistry 295 (27), 9061-9068, 2020 | 27 | 2020 |
| Aza-SAHA derivatives are selective histone deacetylase 10 chemical probes that inhibit polyamine deacetylation and phenocopy HDAC10 knockout RR Steimbach, CJ Herbst-Gervasoni, S Lechner, TM Stewart, G Klinke, ... Journal of the American Chemical Society 144 (41), 18861-18875, 2022 | 13 | 2022 |
| (R, R)-1, 12-Dimethylspermine can mitigate abnormal spermidine accumulation in Snyder–Robinson syndrome TM Stewart, M Khomutov, JR Foley, X Guo, CE Holbert, TT Dunston, ... Journal of Biological Chemistry 295 (10), 3247-3256, 2020 | 13 | 2020 |
| Phenylbutyrate modulates polyamine acetylase and ameliorates Snyder-Robinson syndrome in a Drosophila model and patient cells X Tao, Y Zhu, Z Diaz-Perez, SH Yu, JR Foley, TM Stewart, RA Casero Jr, ... JCI insight 7 (13), 2022 | 8 | 2022 |
| Expanded potential of the polyamine analogue SBP-101 (diethyl dihydroxyhomospermine) as a modulator of polyamine metabolism and cancer therapeutic CE Holbert, JR Foley, T Murray Stewart, RA Casero Jr International journal of molecular sciences 23 (12), 6798, 2022 | 7 | 2022 |
| Identification of a novel substrate-derived spermine oxidase inhibitor TT Dunston, MA Khomutov, SB Gabelli, TM Stewart, JR Foley, ... Acta Naturae (русскоязычная версия) 12 (3 (46)), 140-144, 2020 | 7 | 2020 |
| Histone deacetylase-10 liberates spermidine to support polyamine homeostasis and tumor cell growth TM Stewart, JR Foley, CE Holbert, G Klinke, G Poschet, RR Steimbach, ... Journal of Biological Chemistry 298 (10), 2022 | 6 | 2022 |
| Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder–Robinson syndrome TM Stewart, JR Foley, CE Holbert, M Khomutov, N Rastkari, X Tao, ... EMBO Molecular Medicine 15 (11), e17833, 2023 | 4 | 2023 |
| Polyamine-based nanostructures share polyamine transport mechanisms with native polyamines and their analogues: Significance for polyamine-targeted therapy CE Holbert, JR Foley, A Yu, T Murray Stewart, O Phanstiel IV, D Oupicky, ... Medical Sciences 10 (3), 44, 2022 | 4 | 2022 |
| Hyaluronate-coated perfluoroalkyl polyamine prodrugs as bioactive siRNA delivery systems for the treatment of peritoneal cancers A Yu, S Tang, L Ding, J Foley, W Tang, H Jia, S Panja, CE Holbert, ... Biomaterials advances 136, 212755, 2022 | 4 | 2022 |
| Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis LR Padgett, MR Shinkle, S Rosario, TM Stewart, JR Foley, RA Casero, ... Human Genetics and Genomics Advances 4 (3), 2023 | 3 | 2023 |
| Functional assessment of homozygous ALDH18A1 variants reveals alterations in amino acid and antioxidant metabolism MB Colonna, T Moss, S Mokashi, S Srikanth, JR Jones, JR Foley, ... Human molecular genetics 32 (5), 732-744, 2023 | 3 | 2023 |
| Self-Assembled Alkylated Polyamine Analogs as Supramolecular Anticancer Agents D Sil, S Panja, CM Jogdeo, R Kumar, A Yu, CE Holbert, L Ding, JR Foley, ... Molecules 27 (8), 2441, 2022 | 2 | 2022 |
| Characterizing the homeostatic regulation of the polyamine pathway using the Drosophila melanogaster model system TS Morales, MD Catteau, RB Hepp, J Foley, TM Stewart, RA Casero Jr, ... Gene Reports 24, 101269, 2021 | 1 | 2021 |
| Ivospemin and doxorubicin combination modulates polyamine metabolism to improve survival in a murine ovarian cancer model CE Holbert, JR Foley, AC Nwafor, TA Liu, E Bruckheimer, JK Simpson, ... Cancer Research 84 (6_Supplement), 7154-7154, 2024 | | 2024 |
| Polyamine Catabolism and Its Role in Renal Injury and Fibrosis in Mice Subjected to Repeated Low-Dose Cisplatin Treatment K Zahedi, S Barone, M Brooks, TM Stewart, JR Foley, A Nwafor, ... Biomedicines 12 (3), 640, 2024 | | 2024 |
| Impaired polyamine metabolism causes behavioral and neuroanatomical defects in a mouse model of Snyder-Robinson Syndrome O Akinyele, A Munir, MA Johnson, MS Perez, Y Gao, JR Foley, A Nwafor, ... Disease Models & Mechanisms, dmm. 050639, 2024 | | 2024 |
