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Sheng Yu Ang
Sheng Yu Ang
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Differential GLP-1R binding and activation by peptide and non-peptide agonists
X Zhang, MJ Belousoff, P Zhao, AJ Kooistra, TT Truong, SY Ang, ...
Molecular Cell 80 (3), 485-500. e7, 2020
1232020
ML290 is a biased allosteric agonist at the relaxin receptor RXFP1
M Kocan, M Sarwar, SY Ang, J Xiao, JJ Marugan, MA Hossain, C Wang, ...
Scientific reports 7 (1), 2968, 2017
562017
The Anti-fibrotic Actions of Relaxin Are Mediated Through a NO-sGC-cGMP-Dependent Pathway in Renal Myofibroblasts In Vitro and Enhanced by the NO Donor …
C Wang, BK Kemp-Harper, M Kocan, SY Ang, TD Hewitson, CS Samuel
Frontiers in pharmacology 7, 91, 2016
462016
Signal transduction pathways activated by insulin‐like peptide 5 at the relaxin family peptide RXFP4 receptor
SY Ang, DS Hutchinson, N Patil, BA Evans, RAD Bathgate, ML Halls, ...
British journal of pharmacology 174 (10), 1077-1089, 2017
322017
Structure–function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins
DR Littler, SY Ang, DG Moriel, M Kocan, O Kleifeld, MD Johnson, MT Tran, ...
Journal of Biological Chemistry 292 (36), 15143-15158, 2017
302017
Engineering of a novel simplified human insulin-like peptide 5 agonist
NA Patil, RA Hughes, KJ Rosengren, M Kocan, SY Ang, J Tailhades, ...
Journal of medicinal chemistry 59 (5), 2118-2125, 2016
292016
INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells
SY Ang, BA Evans, DP Poole, R Bron, JJ DiCello, RAD Bathgate, ...
Journal of molecular endocrinology 60 (3), 213-224, 2018
252018
The C-terminus of the B-chain of human insulin-like peptide 5 is critical for cognate RXFP4 receptor activity
NA Patil, RAD Bathgate, M Kocan, SY Ang, J Tailhades, F Separovic, ...
Amino Acids 48, 987-992, 2016
192016
The actions of relaxin family peptides on signal transduction pathways activated by the relaxin family peptide receptor RXFP4
SY Ang, DS Hutchinson, BA Evans, MA Hossain, N Patil, RAD Bathgate, ...
Naunyn-Schmiedeberg's archives of pharmacology 390, 105-111, 2017
122017
Relaxin family peptide receptors RXFP3 and RXFP4
M Kocan, SY Ang, RJ Summers
Encyclopedia of Signaling Molecules, 4615-4630, 2018
42018
Orthosteric, Allosteric and Biased Signalling at the Relaxin-3 Receptor RXFP3
M Kocan, SY Ang, RJ Summers
Neurochemical research 41, 610-619, 2016
32016
GPR55 regulates the responsiveness to, but does not dimerise with, α1A-adrenoceptors
SK Walsh, C Lipina, SY Ang, M Sato, LY Chia, M Kocan, DS Hutchinson, ...
Biochemical Pharmacology 188, 114560, 2021
2021
Signal transduction pathways activated by the orexigenic gut derived hormone insulin-like peptide 5 at relaxin family peptide receptor 4
DS Hutchinson, SY Ang, BA Evans, RJ Summers, M Kocan
Obesity Research & Clinical Practice 13 (1), 41-42, 2019
2019
The gut hormone INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells
SY Ang, BA Evans, DP Poole, R Bron, JJ Dicello, RA Bathgate, M Kocan, ...
Proceedings for Annual Meeting of The Japanese Pharmacological Society …, 2018
2018
Insulin-Like Peptide 5 (INSL5)
SY Ang, RJ Summers
Elsevier, 2018
2018
Signal transduction pathways activated by insulin-like peptide 5 at the relaxin family peptide RXFP4 receptor (vol 174, pg 1077, 2017)
SY Ang, DS Hutchinson, N Patil, BA Evans, RAD Bathgate, ML Halls, ...
BRITISH JOURNAL OF PHARMACOLOGY 174 (24), 4836-4836, 2017
2017
Activation mechanism of Pertussis-like toxins
DR Littler, SY Ang, DG Moriel, M Kocan, O Kleifeld, MD Johnson, MT Tran, ...
2017
This correction provides additional author disclosures to six articles which all appeared in the BJP 174: 10, May 2017 special issue themed section: Recent Progress in the …
SY Ang, DS Hutchinson, N Patil, BA Evans, RAD Bathgate, ML Halls, ...
British Journal of Pharmacology 174, 4836, 2017
2017
Relaxin Family Peptide Receptor 4 (RXFP4) and its Ligand Insulin-like Peptide 5 (INSL5): Signalling Pathways and Physiological Roles
SYU ANG
Monash University, 0
Signal transduction pathways activated by insulin-like peptide 5 (INSL5) at the relaxin family peptide receptor 4 (RXFP4).
SY Ang, DS Hutchinson, N Patil, BA Evans, RAD Bathgate, ML Halls, ...
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