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Derek VanDyke
Derek VanDyke
PhD Candidate, Department of Chemical and Biomolecular Engineering, Johns Hopkins University
Verified email at jhu.edu
Title
Cited by
Cited by
Year
Remotely Triggered Nano-Theranostics For Cancer Applications
A Sneider, D VanDyke, S Paliwal, P Rai
Nanotheranostics 1 (1), 1-22, 2017
1042017
Engineering Remotely Triggered Liposomes to Target Triple Negative Breast Cancer
A Sneider, R Jadia, B Piel, D VanDyke, C Tsiros, P Rai
Oncomedicine 2, 1-13, 2017
342017
Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection
D VanDyke, M Iglesias, J Tomala, A Young, J Smith, JA Perry, E Gebara, ...
Cell Reports 41 (3), 111478, 2022
272022
Nanoparticle Based Combination Treatments for Targeting Multiple Hallmarks of Cancer
D VanDyke, P Kyriacopulos, B Yassini, A Wright, E Burkhart, S Jacek, ...
International Journal of Nano Studies and Technology, 2016
242016
Bioengineered particles expand myelin-specific regulatory T cells and reverse autoreactivity in a mouse model of multiple sclerosis
KR Rhodes, SY Tzeng, M Iglesias, D Lee, K Storm, SY Neshat, ...
Science Advances 9 (22), eadd8693, 2023
112023
Biologics-based degraders—an expanding toolkit for targeted-protein degradation
D VanDyke, JD Taylor, KJ Kaeo, J Hunt, JB Spangler
Current opinion in biotechnology 78, 102807, 2022
92022
Lung tumor–infiltrating Treg have divergent transcriptional profiles and function linked to checkpoint blockade response
AG Dykema, J Zhang, LS Cheung, S Connor, B Zhang, Z Zeng, ...
Science immunology 8 (87), eadg1487, 2023
82023
A suspension cell‐based interaction platform for interrogation of membrane proteins
PJ Krohl, KB Kim, L Lew, D VanDyke, SD Ludwig, JB Spangler
AIChE Journal 66 (12), e16995, 2020
82020
IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function
H Sun, HS Lee, SHJ Kim, MF de Lima, AR Gingras, Q Du, W McLaughlin, ...
Cell reports 42 (8), 2023
42023
Discovery of antibodies targeting multipass transmembrane proteins using a suspension cell-based evolutionary approach
PJ Krohl, J Fine, H Yang, D VanDyke, Z Ang, KB Kim, ...
Cell Reports Methods 3 (3), 2023
22023
Molecular engineering of Interleukin-2 for enhanced therapeutic activity in autoimmune diseases
LM Tomasovic, K Liu, D VanDyke, CS Fabilane, JB Spangler
Biodrugs 38 (2), 227-248, 2024
12024
Rapamycin nanoparticles increase the therapeutic window of engineered interleukin-2 and drive expansion of antigen-specific regulatory T cells for protection against autoimmune …
TK Kishimoto, M Fournier, A Michaud, G Rizzo, C Roy, T Capela, ...
Journal of Autoimmunity 140, 103125, 2023
12023
Synergistic activity of IL-2 mutein with tolerogenic ImmTOR nanoparticles leads to massive expansion of antigen-specific Tregs and protection against autoimmune disease
TK Kishimoto, M Fournier, A Michaud, G Rizzo, C Roy, T Capela, ...
bioRxiv, 2023.05. 15.540840, 2023
12023
Tolerogenic Artificial Antigen Presenting Cells for Selective Tolerance in Autoimmune Disease
G Raimondi, K Rhodes, S Tzeng, MI Lozano, D VanDyke, S Neshat, ...
The Journal of Immunology 208 (1_Supplement), 60.18-60.18, 2022
12022
Methods and materials for targeted expansion of regulatory t cells
J Spangler, D VanDyke
WO Patent WO2020264318A1, 2020
12020
Innovative synthetic signaling technologies for immunotherapy
D VanDyke, W Wang, JB Spangler
Current Opinion in Biomedical Engineering 16, 1-8, 2020
12020
Isolated cardiac myocytes of copper-deficient rats have altered dimensions and responses to osmotic stress.
LJ Heller, D VanDyke, J Smith, B Brokate, JR Prohaska, A Becker
FASEB JOURNAL 13 (5), A768-A768, 1999
11999
Cytokine/Antibody Fusion Protein Design and Evaluation
CS Fabilane, AC Stephenson, EK Leonard, D VanDyke, JB Spangler
Current Protocols 4 (5), e1061, 2024
2024
Redirecting the specificity of tripartite motif containing-21 scaffolds using a novel discovery and design approach
D VanDyke, L Xu, PR Sargunas, RN Gilbreth, M Baca, C Gao, J Hunt, ...
Journal of Biological Chemistry 299 (12), 2023
2023
Augmenting the Persistence and Efficacy of Engineered Regulatory T Cells to Suppress Anti-Drug Antibody Formation
J Rana, D VanDyke, M Munoz, SRP Kumar, M Gonzales, J Spangler, ...
Blood 140 (Supplement 1), 7374-7375, 2022
2022
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