Small ubiquitin-like modifier (SUMO) recognition of a SUMO binding motif: a reversal of the bound orientation J Song, Z Zhang, W Hu, Y Chen Journal of Biological Chemistry 280 (48), 40122-40129, 2005 | 341 | 2005 |
The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane N Berndt, H Yang, B Trinczek, S Betzi, Z Zhang, B Wu, NJ Lawrence, ... Cell Death & Differentiation 17 (11), 1795-1804, 2010 | 122 | 2010 |
Apogossypol derivatives as antagonists of antiapoptotic Bcl-2 family proteins J Wei, S Kitada, MF Rega, A Emdadi, H Yuan, J Cellitti, JL Stebbins, ... Molecular cancer therapeutics 8 (4), 904-913, 2009 | 101 | 2009 |
Novel targeted system to deliver chemotherapeutic drugs to EphA2-expressing cancer cells S Wang, WJ Placzek, JL Stebbins, S Mitra, R Noberini, M Koolpe, Z Zhang, ... Journal of medicinal chemistry 55 (5), 2427-2436, 2012 | 94 | 2012 |
The three-dimensional structure of the C-terminal DNA-binding domain of human Ku70 Z Zhang, L Zhu, D Lin, F Chen, DJ Chen, Y Chen Journal of Biological Chemistry 276 (41), 38231-38236, 2001 | 88 | 2001 |
HTS by NMR of combinatorial libraries: a fragment-based approach to ligand discovery B Wu, Z Zhang, R Noberini, E Barile, M Giulianotti, C Pinilla, RA Houghten, ... Chemistry & biology 20 (1), 19-33, 2013 | 87 | 2013 |
Molecular mechanism of protein kinase recognition and sorting by the Hsp90 kinome-specific cochaperone Cdc37 D Keramisanou, A Aboalroub, Z Zhang, W Liu, D Marshall, A Diviney, ... Molecular cell 62 (2), 260-271, 2016 | 80 | 2016 |
Apogossypol derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins J Wei, S Kitada, MF Rega, JL Stebbins, D Zhai, J Cellitti, H Yuan, ... Journal of medicinal chemistry 52 (14), 4511-4523, 2009 | 76 | 2009 |
Solution structure of the C-terminal domain of Ku80 suggests important sites for protein-protein interactions Z Zhang, W Hu, L Cano, TD Lee, DJ Chen, Y Chen Structure 12 (3), 495-502, 2004 | 75 | 2004 |
Fragment-based design of small molecule X-linked inhibitor of apoptosis protein inhibitors JW Huang, Z Zhang, B Wu, JF Cellitti, X Zhang, R Dahl, CW Shiau, ... Journal of medicinal chemistry 51 (22), 7111-7118, 2008 | 70 | 2008 |
A novel small-molecule binds to the influenza A virus RNA promoter and inhibits viral replication MK Lee, A Bottini, M Kim, MF Bardaro, Z Zhang, M Pellecchia, BS Choi, ... Chemical communications 50 (3), 368-370, 2014 | 69 | 2014 |
Targeted delivery of paclitaxel to EphA2-expressing cancer cells S Wang, R Noberini, JL Stebbins, S Das, Z Zhang, B Wu, S Mitra, S Billet, ... Clinical Cancer Research 19 (1), 128-137, 2013 | 69 | 2013 |
A fragment-based approach for the discovery of isoform-specific p38α inhibitors J Chen, Z Zhang, JL Stebbins, X Zhang, R Hoffman, A Moore, ... ACS Chemical Biology 2 (5), 329-336, 2007 | 67 | 2007 |
SAR by Interligand Nuclear Overhauser Effects (ILOEs) Based Discovery of Acylsulfonamide Compounds Active against Bcl-xL and Mcl-1 MF Rega, B Wu, J Wei, Z Zhang, JF Cellitti, M Pellecchia Journal of medicinal chemistry 54 (17), 6000-6013, 2011 | 65 | 2011 |
BING: Binarized normed gradients for objectness estimation at 300fps MM Cheng, Y Liu, WY Lin, Z Zhang, PL Rosin, PHS Torr Computational Visual Media 5, 3-20, 2019 | 59 | 2019 |
An optically pure apogossypolone derivative as potent pan-active inhibitor of anti-apoptotic bcl-2 family proteins J Wei, JL Stebbins, S Kitada, R Dash, D Zhai, WJ Placzek, B Wu, ... Frontiers in oncology 1, 28, 2011 | 58 | 2011 |
Structure and DNA-binding sites of the SWI1 AT-rich interaction domain (ARID) suggest determinants for sequence-specific DNA recognition S Kim, Z Zhang, S Upchurch, N Isern, Y Chen Journal of Biological Chemistry 279 (16), 16670-16676, 2004 | 58 | 2004 |
A Disalicylic Acid‐Furanyl Derivative Inhibits Ephrin Binding to a Subset of Eph Receptors R Noberini, SK De, Z Zhang, B Wu, D Raveendra‐Panickar, V Chen, ... Chemical biology & drug design 78 (4), 667-678, 2011 | 50 | 2011 |
Synthesis and biological evaluation of Apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins J Wei, S Kitada, JL Stebbins, W Placzek, D Zhai, B Wu, MF Rega, Z Zhang, ... Journal of medicinal chemistry 53 (22), 8000-8011, 2010 | 47 | 2010 |
Determination of the three-dimensional structure of the Mrf2− DNA complex using paramagnetic spin labeling S Cai, L Zhu, Z Zhang, Y Chen Biochemistry 46 (17), 4943-4950, 2007 | 46 | 2007 |