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Cori Fain
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Microglia and perivascular macrophages act as antigen presenting cells to promote CD8 T cell infiltration of the brain
EN Goddery, CE Fain, CG Lipovsky, K Ayasoufi, LT Yokanovich, CS Malo, ...
Frontiers in immunology 12, 726421, 2021
742021
Brain cancer induces systemic immunosuppression through release of non-steroid soluble mediators
K Ayasoufi, CK Pfaller, L Evgin, RH Khadka, ZP Tritz, EN Goddery, ...
Brain 143 (12), 3629-3652, 2020
642020
Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance
X Zhang, VM Pearsall, CM Carver, EJ Atkinson, BDS Clarkson, EM Grund, ...
Nature communications 13 (1), 5671, 2022
572022
Mitochondrial genetics cooperate with nuclear genetics to selectively alter immune cell development/trafficking
TC Beadnell, C Fain, CJ Vivian, JCG King, R Hastings, MA Markiewicz, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (5), 165648, 2020
112020
Conditional Silencing of H-2Db Class I Molecule Expression Modulates the Protective and Pathogenic Kinetics of Virus-Antigen¡VSpecific CD8 T Cell Responses during Theiler's ¡K
ZP Tritz, RC Orozco, CS Malo, K Ayasoufi, CE Fain, RH Khadka, ...
The Journal of Immunology 205 (5), 1228-1238, 2020
102020
Brain resident memory T cells rapidly expand and initiate neuroinflammatory responses following CNS viral infection
K Ayasoufi, DM Wolf, SL Namen, F Jin, ZP Tritz, CK Pfaller, J Zheng, ...
Brain, Behavior, and Immunity 112, 51-76, 2023
92023
Use of heparin to rescue immunosuppressive monocyte reprogramming by glioblastoma-derived extracellular vesicles
BT Himes, CE Fain, ZP Tritz, CL Nesvick, HJ Jin-Lee, PA Geiger, ...
Journal of neurosurgery 138 (5), 1291-1301, 2022
72022
Discrete class I molecules on brain endothelium differentially regulate neuropathology in experimental cerebral malaria
CE Fain, J Zheng, F Jin, K Ayasoufi, Y Wu, MT Lilley, AR Dropik, DM Wolf, ...
Brain 147 (2), 566-589, 2024
42024
Spectral flow cytometry identifies distinct nonneoplastic plasma extracellular vesicle phenotype in glioblastoma patients
A Aibaidula, CE Fain, LC Garcia, A Wier, SM Bouchal, MM Bauman, ...
Neuro-Oncology Advances 5 (1), vdad082, 2023
42023
Antigen presentation by discrete class I molecules on brain endothelium dynamically regulates T-cell mediated neuropathology in experimental cerebral malaria
CE Fain, J Zheng, F Jin, K Ayasoufi, Y Wu, MT Lilley, AR Dropik, DM Wolf, ...
bioRxiv, 2022.10. 30.514412, 2022
42022
Brain resident memory T cells rapidly expand and initiate neuroinflammatory responses following CNS injury and viral infection
K Ayasoufi, DM Wolf, SL Namen, ZP Tritz, F Jin, CK Pfaller, EN Goddery, ...
bioRxiv, 2022.04. 08.487707, 2022
22022
Antigen presentation by CNS-resident microglia and macrophages regulates CD8 T cell infiltration of the brain during central nervous system (CNS) infection
E Goddery, C Fain, C Lipovsky, F Jin, M Hansen, AJ Johnson
The Journal of Immunology 206 (1_Supplement), 11.18-11.18, 2021
22021
Combination immunotherapy of £\PD-1 and extended half-life IL-2 clears established GL261 gliomas in an MHC class I independent fashion
ZP Tritz, K Ayasoufi, C Malo, B Himes, R Khadka, L Yokanovich, ...
The Journal of Immunology 204 (1_Supplement), 169.15-169.15, 2020
22020
H-2kb and H-2db class I molecules on cerebral endothelium differentially modulate Cd8 T cells dynamics and pathological outcomes in experimental cerebral malaria
CE Fain, J Zheng, F Jin, K Ayasoufi, M Chen, A Dropik, R Khadka, ZP Tritz, ...
The Journal of Immunology 208 (1_Supplement), 102.24-102.24, 2022
12022
Rapid activation of brain resident memory T cells following neurological insults
K Ayasoufi, S Namen, E Goddery, Z Tritz, CE Fain, L Yokanovich, F Jin, ...
The Journal of Immunology 202 (1_Supplement), 56.20-56.20, 2019
12019
Neurotropic viral infections induce priming and maintenance of a novel antigen-specific CD8 T cell population within the bone marrow that dysregulates the stem cell niche upon ¡K
R Reesman, D Wolf, Z Tritz, C Pfaller, A Hoyt-Miggelbrink, M Hansen, ...
The Journal of Immunology 212 (1_Supplement), 0169_5932-0169_5932, 2024
2024
IMMU-44. CIRCULATING CELL-FREE DNA DIRECTLY INHIBITS T CELL FUNCTION AND CONTRIBUTES TO PERIPHERAL IMMUNOSUPPRESSION IN EXPERIMENTAL GBM
K Ayasoufi, D Wolf, R Reesman, F Rangel, L Gulbicki, Z Tritz, F Jin, ...
Neuro-Oncology 25 (Suppl 5), v152, 2023
2023
EXTH-77. EXTENDED HALF-LIFE IL-2 SYNERGIZES WITH £D-PD-1 FOR TREATMENT OF PRECLINICAL MURINE GLIOBLASTOMA MODELS
C Owens, Z Tritz, K Ayasoufi, D Wolf, I Parney, M Hanson, J Fang, ...
Neuro-Oncology 25 (Suppl 5), v242, 2023
2023
Anti¡VPD-1 and Extended Half-life IL2 Synergize for Treatment of Murine Glioblastoma Independent of Host MHC Class I Expression
ZP Tritz, K Ayasoufi, DM Wolf, CA Owens, CS Malo, BT Himes, CE Fain, ...
Cancer immunology research 11 (6), 763-776, 2023
2023
Circulating cell-free DNA directly inhibits T cell function and contributes to peripheral immunosuppression in experimental GBM
K Ayasoufi, DM Wolf, RA Reesman, FA Rangel, LR Gulbicki, Z Tritz, F Jin, ...
The Journal of Immunology 210 (1_Supplement), 245.24-245.24, 2023
2023
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