| Increased localization of APP‐C99 in mitochondria‐associated ER membranes causes mitochondrial dysfunction in Alzheimer disease M Pera, D Larrea, C Guardia‐Laguarta, J Montesinos, KR Velasco, ... The EMBO journal 36 (22), 3356-3371, 2017 | 200 | 2017 |
| Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathy N Badiola, RM de Oliveira, F Herrera, C Guardia-Laguarta, SA Goncalves, ... PloS one 6 (10), e26609, 2011 | 162 | 2011 |
| ApoE4 upregulates the activity of mitochondria‐associated ER membranes MD Tambini, M Pera, E Kanter, H Yang, C Guardia‐Laguarta, D Holtzman, ... EMBO reports 17 (1), 27-36, 2016 | 160 | 2016 |
| Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease M Pera, D Alcolea, R Sánchez-Valle, C Guardia-Laguarta, ... Acta Neuropathologica 125, 201-213, 2013 | 125 | 2013 |
| The Alzheimer's disease‐associated C99 fragment of APP regulates cellular cholesterol trafficking J Montesinos, M Pera, D Larrea, C Guardia‐Laguarta, RR Agrawal, ... The EMBO journal 39 (20), e103791, 2020 | 91 | 2020 |
| Mild cholesterol depletion reduces amyloid‐β production by impairing APP trafficking to the cell surface C Guardia‐Laguarta, M Coma, M Pera, J Clarimón, L Sereno, JM Agulló, ... Journal of neurochemistry 110 (1), 220-230, 2009 | 90 | 2009 |
| MFN2 mutations in Charcot–Marie–Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics D Larrea, M Pera, A Gonnelli, R Quintana–Cabrera, HO Akman, ... Human molecular genetics 28 (11), 1782-1800, 2019 | 89 | 2019 |
| Clinical, neuropathologic, and biochemical profile of the amyloid precursor protein I716F mutation C Guardia-Laguarta, M Pera, J Clarimón, JL Molinuevo, R Sánchez-Valle, ... Journal of Neuropathology & Experimental Neurology 69 (1), 53-59, 2010 | 78 | 2010 |
| Autosomal‐dominant Alzheimer's disease mutations at the same codon of amyloid precursor protein differentially alter Aβ production M Suárez‐Calvet, O Belbin, M Pera, N Badiola, J Magrané, ... Journal of neurochemistry 128 (2), 330-339, 2014 | 48 | 2014 |
| gamma-Secretase as a therapeutic target in Alzheimer's disease. C Guardia-Laguarta, M Pera, A Lleo Current drug targets 11 (4), 506-517, 2010 | 46 | 2010 |
| APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice E Area-Gomez, D Larrea, M Pera, RR Agrawal, DN Guilfoyle, L Pirhaji, ... Scientific Reports 10 (1), 4277, 2020 | 40 | 2020 |
| Rare Variants in Calcium Homeostasis Modulator 1 (CALHM1) Found in Early Onset Alzheimer’s Disease Patients Alter Calcium Homeostasis F Rubio-Moscardo, N Seto-Salvia, M Pera, M Bosch-Morato, C Plata, ... PLoS One 8 (9), e74203, 2013 | 33 | 2013 |
| Acetylcholinesterase as an amyloid enhancing factor in PrP82-146 aggregation process M Pera, A Martinez-Otero, L Colombo, M Salmona, D Ruiz-Molina, ... Molecular and Cellular Neuroscience 40 (2), 217-224, 2009 | 30 | 2009 |
| Acetylcholinesterase triggers the aggregation of PrP 106–126 M Pera, S Roman, M Ratia, P Camps, D Munoz-Torrero, L Colombo, ... Biochemical and biophysical research communications 346 (1), 89-94, 2006 | 29 | 2006 |
| The silence of the fats: A MAM’s story about Alzheimer RR Agrawal, J Montesinos, D Larrea, E Area-Gomez, M Pera Neurobiology of Disease 145, 105062, 2020 | 27 | 2020 |
| Undifferentiated and differentiated PC12 cells protected by huprines against injury induced by hydrogen peroxide M Pera, P Camps, D Munoz-Torrero, B Perez, A Badia, MV Clos Guillen PloS one 8 (9), e74344, 2013 | 25 | 2013 |
| MAM and C99, key players in the pathogenesis of Alzheimer’s disease M Pera, J Montesinos, D Larrea, RR Agrawal, KR Velasco, ... International Review of Neurobiology 154, 235-278, 2020 | 17 | 2020 |
| Expanding the multipotent profile of huprine-tacrine heterodimers as disease-modifying anti-Alzheimer agents D Muñoz-Torrero, M Pera, J Relat, M Ratia, C Galdeano, E Viayna, I Sola, ... Neurodegenerative Diseases 10 (1-4), 96-99, 2012 | 11 | 2012 |
| Assessing mitochondrial respiratory bioenergetics in whole cells and isolated organelles by microplate respirometry RR Agrawal, KA Tamucci, M Pera, D Larrea Methods in Cell Biology 155, 157-180, 2020 | 7 | 2020 |
| Effect of acetylcholinesterase inhibitors on AChE-induced PrP106-126 aggregation MV Clos, M Pera, M Ratia, S Román, P Camps, D Muñoz-Torrero, ... Journal of Molecular Neuroscience 30 (1-2), 89, 2006 | 7 | 2006 |
