Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins Y Gong, TI Zack, LGT Morris, K Lin, E Hukkelhoven, R Raheja, IL Tan, ... Nature genetics 46 (6), 588-594, 2014 | 172 | 2014 |
CSF-1 controls cerebellar microglia and is required for motor function and social interaction V Kana, FA Desland, M Casanova-Acebes, P Ayata, A Badimon, E Nabel, ... Journal of Experimental Medicine 216 (10), 2265-2281, 2019 | 161 | 2019 |
Sensitivity of glioblastomas to clinically available MEK inhibitors is defined by neurofibromin 1 deficiency WL See, IL Tan, J Mukherjee, T Nicolaides, RO Pieper Cancer research 72 (13), 3350-3359, 2012 | 112 | 2012 |
Blueprint for a pop-up SARS-CoV-2 testing lab Nature Biotechnology 38 (7), 791-797, 2020 | 53 | 2020 |
CSF1R inhibition depletes tumor-associated macrophages and attenuates tumor progression in a mouse sonic Hedgehog-Medulloblastoma model IL Tan, RDN Arifa, H Rallapalli, V Kana, Z Lao, RM Sanghrajka, ... Oncogene 40 (2), 396-407, 2021 | 50 | 2021 |
Lateral cerebellum is preferentially sensitive to high sonic hedgehog signaling and medulloblastoma formation IL Tan, A Wojcinski, H Rallapalli, Z Lao, RM Sanghrajka, D Stephen, ... Proceedings of the National Academy of Sciences 115 (13), 3392-3397, 2018 | 42 | 2018 |
G-protein coupled receptor kinase (GRK)-5 regulates proliferation of glioblastoma-derived stem cells G Kaur, J Kim, R Kaur, I Tan, O Bloch, MZ Sun, M Safaee, MC Oh, ... Journal of Clinical Neuroscience 20 (7), 1014-1018, 2013 | 36 | 2013 |
RHPS4 G-quadruplex ligand induces anti-proliferative effects in brain tumor cells S Lagah, IL Tan, P Radhakrishnan, RA Hirst, JH Ward, C O’Callaghan, ... PloS one 9 (1), e86187, 2014 | 34 | 2014 |
MEMRI‐based imaging pipeline for guiding preclinical studies in mouse models of sporadic medulloblastoma H Rallapalli, IL Tan, E Volkova, A Wojcinski, BC Darwin, JP Lerch, ... Magnetic resonance in medicine 83 (1), 214-227, 2020 | 6 | 2020 |
Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis IL Tan, AR Perez, RJ Lew, X Sun, A Baldwin, YK Zhu, MM Shah, ... Cell reports 42 (11), 2023 | 4 | 2023 |
CSIG-08. A REGULATORY CIRCUIT OF miR-125b/miR-20b AND Wnt SIGNALING CONTROLS GBM PHENOTYPES THROUGH FZD6-MEDIATED PATHWAYS T Huang, A Alvarez, R Pangeni, C Horbinski, S Lu, CD James, J Raizer, ... Neuro-Oncology 18 (suppl_6), vi42-vi42, 2016 | 2 | 2016 |
TMOD-03. SOMATIC MUTATIONS OF CHROMATIN REGULATOR Kmt2d IN CEREBELLAR PRECURSORS INFLUENCES SHH-MEDULLOBLASTOMA TUMORIGENESIS R Sanghrajka, I Tan, A Wojcinski, H Rallapalli, D Turnbull, K Ge, A Joyner Neuro-Oncology 21 (Suppl 6), vi263, 2019 | 1 | 2019 |
A High Throughput, MEMRI-Based Imaging Pipeline to Study Mouse Models of Sporadic Human Cancer H Rallapalli, IL Tan, A Wojcinski, AL Joyner, DH Turnbull ISMRM, 2017 | 1 | 2017 |
Longitudinal MEMRI Characterization of a Novel Mouse Medulloblastoma Model H Rallapalli, ER Volkova, IL Tan, A Wojcinski, AL Joyner, DH Turnbull Proc. ISMRM 10171, 2016 | 1 | 2016 |
CBIO-19. GENOME SHREDDING ENABLES CRISPR-MEDIATED GLIOBLASTOMA ONCOLYSIS C Fellmann, IL Tan, A Perez, R Lew, K Zhu, M Berger, J Doudna Neuro-Oncology 23 (Suppl 6), vi31, 2021 | | 2021 |
RHPS4 G-Quadruplex Ligand Induces Anti-Proliferative Effects in Brain Tumor S Lagah, IL Tan, P Radhakrishnan, RA Hirst, JH Ward | | 2014 |
RHPS4 G-QUADRUPLEX LIGAND EXERTS ANTI-PROLIFERATIVE EFFECTS IN CHILDHOOD BRAIN TUMOUR CELLS WITH ASSOCIATED TELOMERASE INHIBITION S Lagah, IL Tan, S Malcolm, R Grundy, R Rahman NEURO-ONCOLOGY 14, 10-11, 2012 | | 2012 |
MISMATCH REPAIR-INDEPENDENT DNA DAMAGE DRIVES CHK1 ACTIVATION IN TEMOZOLOMIDE-TREATED GBM CELLS M Ito, W See, J Mukherjee, S Ohba, IL Tan, RO Pieper NEURO-ONCOLOGY 13, 10-11, 2011 | | 2011 |
NF1-DEFICIENCY DEFINES A SUBGROUP OF GBM SENSITIVE TO CLINICALLY AVAILABLE MEK INHIBITORS W See, IL Tan, T Nicolaides, R Pieper NEURO-ONCOLOGY 13, 116-116, 2011 | | 2011 |
MEMRI-guided preclinical trial of an experimental TAM-targeted therapy in mouse medulloblastoma H Rallapalli, IL Tan, A Wojcinski, AL Joyner, DH Turnbull | | |