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John D. Huck
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Diverse functional autoantibodies in patients with COVID-19
EY Wang, T Mao, J Klein, Y Dai, JD Huck, JR Jaycox, F Liu, T Zhou, ...
Nature 595 (7866), 283-288, 2021
8352021
Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-β
A Metelli, BX Wu, B Riesenberg, S Guglietta, JD Huck, C Mills, A Li, ...
Science translational medicine 12 (525), eaay4860, 2020
902020
Dynamic DNA binding licenses a repair factor to bypass roadblocks in search of DNA lesions
MW Brown, Y Kim, GM Williams, JD Huck, JA Surtees, IJ Finkelstein
Nature communications 7 (1), 10607, 2016
632016
Structural and functional analysis of GRP94 in the closed state reveals an essential role for the pre-N domain and a potential client-binding site
JD Huck, NL Que, F Hong, Z Li, DT Gewirth
Cell reports 20 (12), 2800-2809, 2017
622017
Plasmodium infection induces cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein
S Lapidus, F Liu, A Casanovas-Massana, Y Dai, JD Huck, C Lucas, ...
MedRxiv, 2021
332021
Early peak and rapid decline of SARS-CoV-2 seroprevalence in a Swiss metropolitan region
M Emmenegger, E De Cecco, D Lamparter, RPB Jacquat, D Ebner, ...
MedRxiv 531, 20118554, 2020
242020
NECA derivatives exploit the paralog-specific properties of the site 3 side pocket of Grp94, the endoplasmic reticulum Hsp90
JD Huck, NLS Que, RM Immormino, L Shrestha, T Taldone, G Chiosis, ...
Journal of Biological Chemistry 294 (44), 16010-16019, 2019
172019
Exploring the functional complementation between Grp94 and Hsp90
KA Maharaj, NLS Que, F Hong, JD Huck, SK Gill, S Wu, Z Li, DT Gewirth
PloS one 11 (11), e0166271, 2016
172016
Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity
SA Minnie, OG Waltner, KS Ensbey, NS Nemychenkov, CR Schmidt, ...
Science immunology 7 (76), eabo3420, 2022
132022
Campbell
EY Wang, T Mao, J Klein, Y Dai, JD Huck, F Liu, NS Zheng, Z TING, ...
Fournier, JB, Wyllie, AL, CHANTAL BF Vogels, Ott IM, CHANEY C. Kalinich …, 2020
132020
Diverse Functional Autoantibodies in Patients with COVID-19. medRxiv 2020
EY Wang, T Mao, J Klein, Y Dai, JD Huck, F Liu, NS Zheng, T Zhou, ...
Google Scholar, 2020
112020
Structures of Hsp90α and Hsp90β bound to a purine‐scaffold inhibitor reveal an exploitable residue for drug selectivity
JD Huck, NLS Que, S Sharma, T Taldone, G Chiosis, DT Gewirth
Proteins: Structure, Function, and Bioinformatics 87 (10), 869-877, 2019
112019
Population-wide evolution of SARS-CoV-2 immunity tracked by a ternary immunoassay
M Emmenegger, E De Cecco, D Lamparter, RPB Jacquat, J Riou, ...
92020
Plasmodium infection is associated with cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein
S Lapidus, F Liu, A Casanovas-Massana, Y Dai, JD Huck, C Lucas, ...
Scientific reports 12 (1), 22175, 2022
72022
IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii
JT Clark, OE Weizman, DL Aldridge, LA Shallberg, J Eberhard, Z Lanzar, ...
Cell reports 42 (3), 2023
62023
Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region
M Emmenegger, E De Cecco, D Lamparter, RPB Jacquat, J Riou, ...
Iscience 26 (2), 2023
62023
A host–microbiota interactome reveals extensive transkingdom connectivity
ND Sonnert, CE Rosen, AR Ghazi, EA Franzosa, B Duncan-Lowey, ...
Nature 628 (8006), 171-179, 2024
12024
1070 ‘Decoy-resistant’IL-18 in combination with CTLA-4 blockade enhances anti-tumor efficacy in preclinical models of renal cell carcinoma
DA Schoenfeld, D Djureinovic, L Zhang, J Mann, J Huck, L Jilaveanu, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
A modified IL-18 drug in combination with CTLA-4 blockade enhances anti-tumor efficacy in preclinical models of renal cell carcinoma
D Schoenfeld, D Djureinovic, L Zhang, J Mann, J Huck, L Jilaveanu, ...
NaN, NaN-NaN, 2023
2023
Recombinant grp94 chaperones and methods of using the same to modulate glycosylation in fusion proteins
DT Gewirth, JD Huck
US Patent App. 17/191,387, 2021
2021
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Articles 1–20