The Marinopyrroles, Antibiotics of an Unprecedented Structure Class from a Marine Streptomyces sp. CC Hughes, A Prieto-Davo, PR Jensen, W Fenical Organic letters 10 (4), 629-631, 2008 | 331 | 2008 |
Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols DK Johnson, KJ Schillinger, DM Kwait, CV Hughes, EJ McNamara, ... Endothelium 9 (3), 191-203, 2002 | 215 | 2002 |
Concise Total Synthesis of (−)‐Frondosin B Using a Novel Palladium‐Catalyzed Cyclization CC Hughes, D Trauner Angewandte Chemie International Edition 41 (9), 1569-1572, 2002 | 191 | 2002 |
The Ammosamides: Structures of Cell Cycle Modulators from a Marine‐Derived Streptomyces Species CC Hughes, JB MacMillan, SP Gaudêncio, PR Jensen, W Fenical Angewandte Chemie International Edition 48 (4), 725-727, 2009 | 176 | 2009 |
Antibacterials from the sea CC Hughes, W Fenical Chemistry–A European Journal 16 (42), 12512-12525, 2010 | 173 | 2010 |
Concise synthesis of (±)-rhazinilam through direct coupling AL Bowie, CC Hughes, D Trauner Organic letters 7 (23), 5207-5209, 2005 | 152 | 2005 |
Total synthesis of (−)-heptemerone B and (−)-guanacastepene E AK Miller, CC Hughes, JJ Kennedy-Smith, SN Gradl, D Trauner Journal of the American Chemical Society 128 (51), 17057-17062, 2006 | 132 | 2006 |
Bile salt–induced intermolecular disulfide bond formation activates Vibrio cholerae virulence M Yang, Z Liu, C Hughes, AM Stern, H Wang, Z Zhong, B Kan, W Fenical, ... Proceedings of the National Academy of Sciences 110 (6), 2348-2353, 2013 | 117 | 2013 |
Marinopyrrole A target elucidation by acyl dye transfer CC Hughes, YL Yang, WT Liu, PC Dorrestein, JJL Clair, W Fenical Journal of the American Chemical Society 131 (34), 12094-12096, 2009 | 113 | 2009 |
Ammosamides A and B target myosin CC Hughes, JB MacMillan, SP Gaudêncio, W Fenical, JJ La Clair Angewandte Chemie 121 (4), 742-746, 2009 | 111 | 2009 |
Structures, reactivities, and antibiotic properties of the marinopyrroles A− F CC Hughes, CA Kauffman, PR Jensen, W Fenical The Journal of organic chemistry 75 (10), 3240-3250, 2010 | 107 | 2010 |
Flavoenzyme-Catalyzed Atropo-Selective N,C-Bipyrrole Homocoupling in Marinopyrrole Biosynthesis K Yamanaka, KS Ryan, TAM Gulder, CC Hughes, BS Moore Journal of the American Chemical Society 134 (30), 12434-12437, 2012 | 87 | 2012 |
Palladium-catalyzed couplings to nucleophilic heteroarenes: the total synthesis of (−)-frondosin B CC Hughes, D Trauner Tetrahedron 60 (43), 9675-9686, 2004 | 78 | 2004 |
Function-Oriented Biosynthesis of β-Lactone Proteasome Inhibitors in Salinispora tropica M Nett, TAM Gulder, AJ Kale, CC Hughes, BS Moore Journal of medicinal chemistry 52 (19), 6163-6167, 2009 | 74 | 2009 |
An electrochemical approach to the guanacastepenes CC Hughes, AK Miller, D Trauner Organic Letters 7 (16), 3425-3428, 2005 | 73 | 2005 |
Pharmacological properties of the marine natural product marinopyrrole A against methicillin-resistant Staphylococcus aureus NM Haste, CC Hughes, DN Tran, W Fenical, PR Jensen, V Nizet, ... Antimicrobial agents and chemotherapy 55 (7), 3305-3312, 2011 | 69 | 2011 |
Discovery, biosynthesis and stress-related accumulation of dolabradiene-derived defenses in maize S Mafu, Y Ding, KM Murphy, O Yaacoobi, JB Addison, Q Wang, Z Shen, ... Plant physiology 176 (4), 2677-2690, 2018 | 67 | 2018 |
Synthetic studies toward the guanacastepenes CC Hughes, JJ Kennedy-Smith, D Trauner Organic Letters 5 (22), 4113-4115, 2003 | 66 | 2003 |
The Total Synthesis of (−)‐Amathaspiramide F CC Hughes, D Trauner Angewandte Chemie 114 (23), 4738-4741, 2002 | 63 | 2002 |
Total synthesis of the ammosamides CC Hughes, W Fenical Journal of the American Chemical Society 132 (8), 2528-2529, 2010 | 62 | 2010 |