Chambers C. Hughes
Chambers C. Hughes
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The Marinopyrroles, Antibiotics of an Unprecedented Structure Class from a Marine Streptomyces sp.
CC Hughes, A Prieto-Davo, PR Jensen, W Fenical
Organic letters 10 (4), 629-631, 2008
Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols
DK Johnson, KJ Schillinger, DM Kwait, CV Hughes, EJ McNamara, ...
Endothelium 9 (3), 191-203, 2002
Concise Total Synthesis of (−)‐Frondosin B Using a Novel Palladium‐Catalyzed Cyclization
CC Hughes, D Trauner
Angewandte Chemie International Edition 41 (9), 1569-1572, 2002
The Ammosamides: Structures of Cell Cycle Modulators from a Marine‐Derived Streptomyces Species
CC Hughes, JB MacMillan, SP Gaudêncio, PR Jensen, W Fenical
Angewandte Chemie International Edition 48 (4), 725-727, 2009
Antibacterials from the sea
CC Hughes, W Fenical
Chemistry–A European Journal 16 (42), 12512-12525, 2010
Concise synthesis of (±)-rhazinilam through direct coupling
AL Bowie, CC Hughes, D Trauner
Organic letters 7 (23), 5207-5209, 2005
Total synthesis of (−)-heptemerone B and (−)-guanacastepene E
AK Miller, CC Hughes, JJ Kennedy-Smith, SN Gradl, D Trauner
Journal of the American Chemical Society 128 (51), 17057-17062, 2006
Bile salt–induced intermolecular disulfide bond formation activates Vibrio cholerae virulence
M Yang, Z Liu, C Hughes, AM Stern, H Wang, Z Zhong, B Kan, W Fenical, ...
Proceedings of the National Academy of Sciences 110 (6), 2348-2353, 2013
Marinopyrrole A target elucidation by acyl dye transfer
CC Hughes, YL Yang, WT Liu, PC Dorrestein, JJL Clair, W Fenical
Journal of the American Chemical Society 131 (34), 12094-12096, 2009
Ammosamides A and B target myosin
CC Hughes, JB MacMillan, SP Gaudêncio, W Fenical, JJ La Clair
Angewandte Chemie 121 (4), 742-746, 2009
Structures, reactivities, and antibiotic properties of the marinopyrroles A− F
CC Hughes, CA Kauffman, PR Jensen, W Fenical
The Journal of organic chemistry 75 (10), 3240-3250, 2010
Flavoenzyme-Catalyzed Atropo-Selective N,C-Bipyrrole Homocoupling in Marinopyrrole Biosynthesis
K Yamanaka, KS Ryan, TAM Gulder, CC Hughes, BS Moore
Journal of the American Chemical Society 134 (30), 12434-12437, 2012
Palladium-catalyzed couplings to nucleophilic heteroarenes: the total synthesis of (−)-frondosin B
CC Hughes, D Trauner
Tetrahedron 60 (43), 9675-9686, 2004
Function-Oriented Biosynthesis of β-Lactone Proteasome Inhibitors in Salinispora tropica
M Nett, TAM Gulder, AJ Kale, CC Hughes, BS Moore
Journal of medicinal chemistry 52 (19), 6163-6167, 2009
An electrochemical approach to the guanacastepenes
CC Hughes, AK Miller, D Trauner
Organic Letters 7 (16), 3425-3428, 2005
Pharmacological properties of the marine natural product marinopyrrole A against methicillin-resistant Staphylococcus aureus
NM Haste, CC Hughes, DN Tran, W Fenical, PR Jensen, V Nizet, ...
Antimicrobial agents and chemotherapy 55 (7), 3305-3312, 2011
Discovery, biosynthesis and stress-related accumulation of dolabradiene-derived defenses in maize
S Mafu, Y Ding, KM Murphy, O Yaacoobi, JB Addison, Q Wang, Z Shen, ...
Plant physiology 176 (4), 2677-2690, 2018
Synthetic studies toward the guanacastepenes
CC Hughes, JJ Kennedy-Smith, D Trauner
Organic Letters 5 (22), 4113-4115, 2003
The Total Synthesis of (−)‐Amathaspiramide F
CC Hughes, D Trauner
Angewandte Chemie 114 (23), 4738-4741, 2002
Total synthesis of the ammosamides
CC Hughes, W Fenical
Journal of the American Chemical Society 132 (8), 2528-2529, 2010
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