Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy DM Francis, MP Manspeaker, A Schudel, LF Sestito, MJ O’Melia, ... Science translational medicine 12 (563), eaay3575, 2020 | 196 | 2020 |
Thermosensitive hydrogel releasing nitric oxide donor and anti-CTLA-4 micelles for anti-tumor immunotherapy J Kim, DM Francis, LF Sestito, PA Archer, MP Manspeaker, MJ O’Melia, ... Nature Communications 13 (1), 1479, 2022 | 94 | 2022 |
Multiphoton Microscopy and Fluorescence Lifetime Imaging: Applications in Biology and Medicine T Baldeweck, M Balu, A Batista, W Vecker, VV Belousov, HG Breinig, ... Walter de Gruyter GmbH & Co KG, 2018 | 59 | 2018 |
Tumor-draining lymph nodes are survival niches that support T cell priming against lymphatic transported tumor antigen and effects of immune checkpoint blockade in TNBC MJ O’Melia, MP Manspeaker, SN Thomas Cancer Immunology, Immunotherapy, 1-17, 2021 | 40 | 2021 |
Lymph node subcapsular sinus microenvironment-on-a-chip modeling shear flow relevant to lymphatic metastasis and immune cell homing KG Birmingham, MJ O'Melia, S Bordy, DR Aguilar, B El-Reyas, G Lesinski, ... Iscience 23 (11), 2020 | 39 | 2020 |
The biophysics of lymphatic transport: engineering tools and immunological consequences MJ O'Melia, AW Lund, SN Thomas Iscience 22, 28-43, 2019 | 39 | 2019 |
Quality of CD8+ T cell immunity evoked in lymph nodes is compartmentalized by route of antigen transport and functional in tumor context MJ O’melia, NA Rohner, MP Manspeaker, DM Francis, HT Kissick, ... Science Advances 6 (50), eabd7134, 2020 | 34 | 2020 |
Cancer cell plasticity and MHC-II–mediated immune tolerance promote breast cancer metastasis to lymph nodes PJ Lei, ER Pereira, P Andersson, Z Amoozgar, JW Van Wijnbergen, ... Journal of Experimental Medicine 220 (9), e20221847, 2023 | 16 | 2023 |
Synthetic matrix scaffolds engineer the in vivo tumor immune microenvironment for immunotherapy screening MJ O'Melia, A Mulero‐Russe, J Kim, A Pybus, D DeRyckere, L Wood, ... Advanced Materials 34 (10), 2108084, 2022 | 14 | 2022 |
Fluorometric quantification of single-cell velocities to investigate cancer metastasis EE Edwards, KG Birmingham, MJ O’Melia, J Oh, SN Thomas Cell systems 7 (5), 496-509. e6, 2018 | 13 | 2018 |
Analyzing mechanisms of metastatic cancer cell adhesive phenotype leveraging preparative adhesion chromatography microfluidic KG Birmingham, MJ O'Melia, D Ban, J Mouw, EE Edwards, AI Marcus, ... Advanced biosystems 3 (3), 1800328, 2019 | 11 | 2019 |
FLIM data analysis of NADH and Tryptophan autofluorescence in prostate cancer cells MJ O'Melia, H Wallrabe, Z Svindrych, S Rehman, A Periasamy Multiphoton Microscopy in the Biomedical Sciences XVI 9712, 261-266, 2016 | 11 | 2016 |
Quantitation of lymphatic transport mechanism and barrier influences on lymph node-resident leukocyte access to lymph-borne macromolecules and drug delivery systems PA Archer, LF Sestito, MP Manspeaker, MJ O’Melia, NA Rohner, ... Drug delivery and translational research 11 (6), 2328-2343, 2021 | 10 | 2021 |
Elicitation of stem-like CD8+ T cell responses via lymph node-targeted chemoimmunotherapy evokes systemic tumor control MP Manspeaker, MJ O'Melia, SN Thomas Journal for Immunotherapy of Cancer 10 (9), 2022 | 8 | 2022 |
Investigation of prostate cancer cells using NADH and Tryptophan as biomarker: Multiphoton FLIM-FRET microscopy S Rehman, MJ O'Melia, H Wallrabe, Z Svindrych, D Chandra, ... Multiphoton Microscopy in the Biomedical Sciences XVI 9712, 56-60, 2016 | 7 | 2016 |
Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy. Sci Transl Med 2020; 12 DM Francis, MP Manspeaker, A Schudel, LF Sestito, MJ O'Melia, ... | 4 | |
Lymphatic muscle cells are unique cells that undergo aging induced changes PJ Lei, KJ Ruscic, K Roh, JJ Rajotte, MJ O’Melia, EM Bouta, M Marquez, ... BioRxiv, 2023.11. 18.567621, 2023 | 3 | 2023 |
Cancer immunotherapy responses persist after lymph node resection H Zhou, JW Baish, MJ O’Melia, LB Darragh, E Specht, J Czapla, P Lei, ... bioRxiv, 2023.09. 19.558262, 2023 | 3 | 2023 |
Lymphatics drain nanoparticles from tumours MJ O’Melia, SN Thomas Nature Materials 22 (11), 1287-1288, 2023 | 2 | 2023 |
FLIM-FRET microscopy SR Alam, MJO Melia, H Wallrabe, Z Svindrych, D Chandra, S Joshi, ... Multiphoton Microscopy and Fluorescence Lifetime Imaging: Applications in …, 2018 | 2 | 2018 |