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Meghan J. O'Melia
Meghan J. O'Melia
Harvard Medical School/Massachusetts General Hospital
Verified email at mgh.harvard.edu
Title
Cited by
Cited by
Year
Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy
DM Francis, MP Manspeaker, A Schudel, LF Sestito, MJ O’Melia, ...
Science translational medicine 12 (563), eaay3575, 2020
1962020
Thermosensitive hydrogel releasing nitric oxide donor and anti-CTLA-4 micelles for anti-tumor immunotherapy
J Kim, DM Francis, LF Sestito, PA Archer, MP Manspeaker, MJ O’Melia, ...
Nature Communications 13 (1), 1479, 2022
942022
Multiphoton Microscopy and Fluorescence Lifetime Imaging: Applications in Biology and Medicine
T Baldeweck, M Balu, A Batista, W Vecker, VV Belousov, HG Breinig, ...
Walter de Gruyter GmbH & Co KG, 2018
592018
Tumor-draining lymph nodes are survival niches that support T cell priming against lymphatic transported tumor antigen and effects of immune checkpoint blockade in TNBC
MJ O’Melia, MP Manspeaker, SN Thomas
Cancer Immunology, Immunotherapy, 1-17, 2021
402021
Lymph node subcapsular sinus microenvironment-on-a-chip modeling shear flow relevant to lymphatic metastasis and immune cell homing
KG Birmingham, MJ O'Melia, S Bordy, DR Aguilar, B El-Reyas, G Lesinski, ...
Iscience 23 (11), 2020
392020
The biophysics of lymphatic transport: engineering tools and immunological consequences
MJ O'Melia, AW Lund, SN Thomas
Iscience 22, 28-43, 2019
392019
Quality of CD8+ T cell immunity evoked in lymph nodes is compartmentalized by route of antigen transport and functional in tumor context
MJ O’melia, NA Rohner, MP Manspeaker, DM Francis, HT Kissick, ...
Science Advances 6 (50), eabd7134, 2020
342020
Cancer cell plasticity and MHC-II–mediated immune tolerance promote breast cancer metastasis to lymph nodes
PJ Lei, ER Pereira, P Andersson, Z Amoozgar, JW Van Wijnbergen, ...
Journal of Experimental Medicine 220 (9), e20221847, 2023
162023
Synthetic matrix scaffolds engineer the in vivo tumor immune microenvironment for immunotherapy screening
MJ O'Melia, A Mulero‐Russe, J Kim, A Pybus, D DeRyckere, L Wood, ...
Advanced Materials 34 (10), 2108084, 2022
142022
Fluorometric quantification of single-cell velocities to investigate cancer metastasis
EE Edwards, KG Birmingham, MJ O’Melia, J Oh, SN Thomas
Cell systems 7 (5), 496-509. e6, 2018
132018
Analyzing mechanisms of metastatic cancer cell adhesive phenotype leveraging preparative adhesion chromatography microfluidic
KG Birmingham, MJ O'Melia, D Ban, J Mouw, EE Edwards, AI Marcus, ...
Advanced biosystems 3 (3), 1800328, 2019
112019
FLIM data analysis of NADH and Tryptophan autofluorescence in prostate cancer cells
MJ O'Melia, H Wallrabe, Z Svindrych, S Rehman, A Periasamy
Multiphoton Microscopy in the Biomedical Sciences XVI 9712, 261-266, 2016
112016
Quantitation of lymphatic transport mechanism and barrier influences on lymph node-resident leukocyte access to lymph-borne macromolecules and drug delivery systems
PA Archer, LF Sestito, MP Manspeaker, MJ O’Melia, NA Rohner, ...
Drug delivery and translational research 11 (6), 2328-2343, 2021
102021
Elicitation of stem-like CD8+ T cell responses via lymph node-targeted chemoimmunotherapy evokes systemic tumor control
MP Manspeaker, MJ O'Melia, SN Thomas
Journal for Immunotherapy of Cancer 10 (9), 2022
82022
Investigation of prostate cancer cells using NADH and Tryptophan as biomarker: Multiphoton FLIM-FRET microscopy
S Rehman, MJ O'Melia, H Wallrabe, Z Svindrych, D Chandra, ...
Multiphoton Microscopy in the Biomedical Sciences XVI 9712, 56-60, 2016
72016
Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy. Sci Transl Med 2020; 12
DM Francis, MP Manspeaker, A Schudel, LF Sestito, MJ O'Melia, ...
4
Lymphatic muscle cells are unique cells that undergo aging induced changes
PJ Lei, KJ Ruscic, K Roh, JJ Rajotte, MJ O’Melia, EM Bouta, M Marquez, ...
BioRxiv, 2023.11. 18.567621, 2023
32023
Cancer immunotherapy responses persist after lymph node resection
H Zhou, JW Baish, MJ O’Melia, LB Darragh, E Specht, J Czapla, P Lei, ...
bioRxiv, 2023.09. 19.558262, 2023
32023
Lymphatics drain nanoparticles from tumours
MJ O’Melia, SN Thomas
Nature Materials 22 (11), 1287-1288, 2023
22023
FLIM-FRET microscopy
SR Alam, MJO Melia, H Wallrabe, Z Svindrych, D Chandra, S Joshi, ...
Multiphoton Microscopy and Fluorescence Lifetime Imaging: Applications in …, 2018
22018
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