Multiple mechanisms of zinc-mediated inhibition for the apoptotic caspases-3,-6,-7, and-8 SJ Eron, DJ MacPherson, KB Dagbay, JA Hardy ACS chemical biology 13 (5), 1279-1290, 2018 | 80 | 2018 |
Reprogramming caspase-7 specificity by regio-specific mutations and selection provides alternate solutions for substrate recognition ME Hill, DJ MacPherson, P Wu, O Julien, JA Wells, JA Hardy ACS chemical biology 11 (6), 1603-1612, 2016 | 44 | 2016 |
Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry T Dixon, D MacPherson, B Mostofian, T Dauzhenka, S Lotz, D McGee, ... Nature communications 13 (1), 5884, 2022 | 34 | 2022 |
Tri-arginine exosite patch of caspase-6 recruits substrates for hydrolysis DJ MacPherson, CL Mills, MJ Ondrechen, JA Hardy Journal of Biological Chemistry 294 (1), 71-88, 2019 | 24 | 2019 |
A fluorescence-activatable reporter of flavivirus NS2B–NS3 protease activity enables live imaging of infection in single cells and viral plaques JL Arias-Arias, DJ MacPherson, ME Hill, JA Hardy, R Mora-Rodríguez Journal of Biological Chemistry 295 (8), 2212-2226, 2020 | 21 | 2020 |
Atomic-resolution prediction of degrader-mediated ternary complex structures by combining molecular simulations with hydrogen deuterium exchange T Dixon, D MacPherson, B Mostofian, T Dauzhenka, S Lotz, D McGee, ... Biorxiv, 2021.09. 26.461830, 2021 | 12 | 2021 |