Shankar Chinta
Shankar Chinta
Touro University, California
Verified email at - Homepage
Cited by
Cited by
Dopaminergic neurons
SJ Chinta, JK Andersen
The international journal of biochemistry & cell biology 37 (5), 942-946, 2005
Mitochondrial alpha-synuclein accumulation impairs complex I function in dopaminergic neurons and results in increased mitophagy in vivo
SJ Chinta, JK Mallajosyula, A Rane, JK Andersen
Neuroscience letters 486 (3), 235-239, 2010
Cellular senescence is induced by the environmental neurotoxin paraquat and contributes to neuropathology linked to Parkinson’s disease
SJ Chinta, G Woods, M Demaria, A Rane, Y Zou, A McQuade, ...
Cell reports 22 (4), 930-940, 2018
Redox imbalance in Parkinson's disease
SJ Chinta, JK Andersen
Biochimica et Biophysica Acta (BBA)-General Subjects 1780 (11), 1362-1367, 2008
MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology
JK Mallajosyula, D Kaur, SJ Chinta, S Rajagopalan, A Rane, DG Nicholls, ...
PloS one 3 (2), e1616, 2008
Cellular senescence and the aging brain
SJ Chinta, G Woods, A Rane, M Demaria, J Campisi, JK Andersen
Experimental gerontology 68, 3-7, 2015
Environmental stress, ageing and glial cell senescence: a novel mechanistic link to Parkinson's disease?
SJ Chinta, CA Lieu, M DeMaria, RM Laberge, J Campisi, JK Andersen
Journal of internal medicine 273 (5), 429-436, 2013
Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: implications for …
A Siddiqui, SJ Chinta, JK Mallajosyula, S Rajagopolan, I Hanson, A Rane, ...
Free Radical Biology and Medicine 53 (4), 993-1003, 2012
Increased murine neonatal iron intake results in Parkinson-like neurodegeneration with age
D Kaur, J Peng, SJ Chinta, S Rajagopalan, DA Di Monte, RA Cherny, ...
Neurobiology of aging 28 (6), 907-913, 2007
Inducible alterations of glutathione levels in adult dopaminergic midbrain neurons result in nigrostriatal degeneration
SJ Chinta, MJ Kumar, M Hsu, S Rajagopalan, D Kaur, A Rane, ...
Journal of Neuroscience 27 (51), 13997-14006, 2007
Reversible inhibition of mitochondrial complex I activity following chronic dopaminergic glutathione depletion in vitro: implications for Parkinson's disease
SJ Chinta, JK Andersen
Free Radical Biology and Medicine 41 (9), 1442-1448, 2006
Mitochondrial quality control via the PGC1α-TFEB signaling pathway is compromised by parkin Q311X mutation but independently restored by rapamycin
A Siddiqui, D Bhaumik, SJ Chinta, A Rane, S Rajagopalan, CA Lieu, ...
Journal of Neuroscience 35 (37), 12833-12844, 2015
Taurine deficiency as a driver of aging
P Singh, K Gollapalli, S Mangiola, D Schranner, MA Yusuf, M Chamoli, ...
Science 380 (6649), eabn9257, 2023
Nitrosylation and nitration of mitochondrial complex I in Parkinson's disease
SJ Chinta, JK Andersen
Free Radical Research 45 (1), 53-58, 2011
A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine
HV Pai, RP Kommaddi, SJ Chinta, T Mori, MR Boyd, V Ravindranath
Journal of Biological Chemistry 279 (26), 27383-27389, 2004
A disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial and cellular iron dysregulation in …
DW Lee, D Kaur, SJ Chinta, S Rajagopalan, JK Andersen
Antioxidants & redox signaling 11 (9), 2083-2094, 2009
Sembragiline: a novel, selective monoamine oxidase type B inhibitor for the treatment of Alzheimer’s disease
E Borroni, B Bohrmann, F Grueninger, E Prinssen, S Nave, H Loetscher, ...
Journal of Pharmacology and Experimental Therapeutics 362 (3), 413-423, 2017
Constitutive expression and localization of the major drug metabolizing enzyme, cytochrome P4502D in human brain
SJ Chinta, HV Pai, SC Upadhya, MR Boyd, V Ravindranath
Molecular brain research 103 (1-2), 49-61, 2002
Anti-inflammatory role of the isoflavone diadzein in lipopolysaccharide-stimulated microglia: implications for Parkinson’s disease
SJ Chinta, A Ganesan, P Reis-Rodrigues, GJ Lithgow, JK Andersen
Neurotoxicity research 23, 145-153, 2013
Reactive oxygen species regulation by AIF-and complex I-depleted brain mitochondria
SJ Chinta, A Rane, N Yadava, JK Andersen, DG Nicholls, BM Polster
Free Radical Biology and Medicine 46 (7), 939-947, 2009
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