Functional modeling of tight junctions in intestinal cell monolayers using polyethylene glycol oligomers CJ Watson, M Rowland, G Warhurst American Journal of Physiology-Cell Physiology 281 (2), C388-C397, 2001 | 293 | 2001 |
Genotypic and Physiological Characterization of Saccharomyces boulardii, the Probiotic Strain of Saccharomyces cerevisiae L Edwards-Ingram, P Gitsham, N Burton, G Warhurst, I Clarke, D Hoyle, ... Applied and environmental microbiology 73 (8), 2458-2467, 2007 | 251 | 2007 |
Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of poly(ethylene glycol) and D‐peptides YL He, S Murby, G Warhurst, L Gifford, D Walker, J Ayrton, R Eastmond, ... Journal of pharmaceutical sciences 87 (5), 626-633, 1998 | 217 | 1998 |
Kinetic profiling of P-glycoprotein-mediated drug efflux in rat and human intestinal epithelia RH Stephens, CA O'Neill, A Warhurst, GL Carlson, M Rowland, ... Journal of Pharmacology and Experimental Therapeutics 296 (2), 584-591, 2001 | 212 | 2001 |
Interferon γ induces translocation of commensal Escherichia coli across gut epithelial cells via a lipid raft--mediated process E Clark, C Hoare, J Tanianis-Hughes, GL Carlson, G Warhurst Gastroenterology 128 (5), 1258-1267, 2005 | 205 | 2005 |
Interferon-γ selectively increases epithelial permeability to large molecules by activating different populations of paracellular pores CJ Watson, CJ Hoare, DR Garrod, GL Carlson, G Warhurst Journal of cell science 118 (22), 5221-5230, 2005 | 204 | 2005 |
Modulation of the permeability of H2 receptor antagonists cimetidine and ranitidine by P-glycoprotein in rat intestine and the human colonic cell line Caco-2 A Collett, NB Higgs, E Sims, M Rowland, G Warhurst Journal of Pharmacology and Experimental Therapeutics 288 (1), 171-178, 1999 | 179 | 1999 |
Fatty acids stimulate cholecystokinin secretion via an acyl chain length-specific, Ca2+-dependent mechanism in the enteroendocrine cell line STC-1 JT McLaughlin, RB Lomax, L Hall, GJ Dockray, DG Thompson, ... The Journal of physiology 513 (Pt 1), 11, 1998 | 178 | 1998 |
Accuracy of LightCycler® SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta … P Dark, B Blackwood, S Gates, D McAuley, GD Perkins, R McMullan, ... Intensive care medicine 41, 21-33, 2015 | 173 | 2015 |
Bench-to-bedside review: the promise of rapid infection diagnosis during sepsis using polymerase chain reaction-based pathogen detection PM Dark, P Dean, G Warhurst Critical care 13, 1-6, 2009 | 147 | 2009 |
Glutamine deprivation facilitates tumour necrosis factor induced bacterial translocation in Caco-2 cells by depletion of enterocyte fuel substrate EC Clark, SD Patel, PR Chadwick, G Warhurst, A Curry, GL Carlson Gut 52 (2), 224-230, 2003 | 144 | 2003 |
Interferon γ induces differential upregulation of α and β chemokine secretion in colonic epithelial cell lines AC Warhurst, SJ Hopkins, G Warhurst Gut 42 (2), 208-213, 1998 | 134 | 1998 |
Region-dependent modulation of intestinal permeability by drug efflux transporters: in vitro studies in mdr1a (−/−) mouse intestine RH Stephens, J Tanianis-Hughes, NB Higgs, M Humphrey, G Warhurst Journal of Pharmacology and Experimental Therapeutics 303 (3), 1095-1101, 2002 | 124 | 2002 |
Comparison of HT29-18-C1 and Caco-2 Cell Lines as Models for Studying Intestinal Paracellular Drug Absorption A Collett, E Sims, D Walker, YL He, J Ayrton, M Rowland, G Warhurst Pharmaceutical research 13, 216-221, 1996 | 121 | 1996 |
Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro–in vivo extrapolation of oral drug absorption MD Harwood, S Neuhoff, GL Carlson, G Warhurst, A Rostami‐Hodjegan Biopharmaceutics & drug disposition 34 (1), 2-28, 2013 | 120 | 2013 |
Fatty acid‐induced cholecystokinin secretion and changes in intracellular Ca2+ in two enteroendocrine cell lines, STC‐1 and GLUTag SS Sidhu, DG Thompson, G Warhurst, RM Case, RSP Benson The Journal of physiology 528 (1), 165-176, 2000 | 99 | 2000 |
Rapid induction of P-glycoprotein expression by high permeability compounds in colonic cells in vitro: a possible source of transporter mediated drug interactions? A Collett, J Tanianis-Hughes, G Warhurst Biochemical pharmacology 68 (4), 783-790, 2004 | 96 | 2004 |
Synthesis and degradation of prostaglandin E2 in the epithelial and sub-epithelial layers of the rat intestine GS Smith, G Warhurst, LA Turnberg Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 713 (3), 684-687, 1982 | 90 | 1982 |
Quantitative proteomics of clinically relevant drug-metabolizing enzymes and drug transporters and their intercorrelations in the human small intestine N Couto, ZM Al-Majdoub, S Gibson, PJ Davies, B Achour, MD Harwood, ... Drug Metabolism and Disposition 48 (4), 245-254, 2020 | 86 | 2020 |
Characteristics of two basolateral potassium channel populations in human colonic crypts. RB Lomax, G Warhurst, GI Sandle Gut 38 (2), 243-247, 1996 | 85 | 1996 |