Oligodendrocyte precursors migrate along vasculature in the developing nervous system HH Tsai, J Niu, R Munji, D Davalos, J Chang, H Zhang, AC Tien, CJ Kuo, ... Science 351 (6271), 379-384, 2016 | 405 | 2016 |
A Notch updated AC Tien, A Rajan, HJ Bellen Journal of Cell Biology 184 (5), 621-629, 2009 | 233 | 2009 |
Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons SB Yang, AC Tien, G Boddupalli, AW Xu, YN Jan, LY Jan Neuron 75 (3), 425-436, 2012 | 228 | 2012 |
A glial signature and Wnt7 signaling regulate glioma-vascular interactions and tumor microenvironment A Griveau, G Seano, SJ Shelton, R Kupp, A Jahangiri, K Obernier, ... Cancer cell 33 (5), 874-889. e7, 2018 | 209 | 2018 |
Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord AC Tien, HH Tsai, AV Molofsky, M McMahon, LC Foo, A Kaul, ... Development 139 (14), 2477-2487, 2012 | 144 | 2012 |
POINT: a database for the prediction of protein–protein interactions based on the orthologous interactome TW Huang, AC Tien, WS Huang, YCG Lee, CL Peng, HH Tseng, CY Kao, ... Bioinformatics 20 (17), 3273-3276, 2004 | 144 | 2004 |
Phosphorylation state of Olig2 regulates proliferation of neural progenitors Y Sun, DH Meijer, JA Alberta, S Mehta, MF Kane, AC Tien, H Fu, ... Neuron 69 (5), 906-917, 2011 | 140 | 2011 |
Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles T Ohyama, P Verstreken, CV Ly, T Rosenmund, A Rajan, AC Tien, ... The Journal of cell biology 179 (7), 1481-1496, 2007 | 128 | 2007 |
Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity SB Yang, HY Lee, DM Young, AC Tien, A Rowson-Baldwin, YY Shu, ... Journal of molecular medicine 90, 575-585, 2012 | 111 | 2012 |
The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors A Rajan, AC Tien, CM Haueter, KL Schulze, HJ Bellen Nature cell biology 11 (7), 815-824, 2009 | 109 | 2009 |
Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster AC Tien, A Rajan, KL Schulze, HD Ryoo, M Acar, H Steller, HJ Bellen The Journal of cell biology 182 (6), 1113-1125, 2008 | 79 | 2008 |
Senseless and Daughterless confer neuronal identity to epithelial cells in the Drosophila wing margin H Jafar-Nejad, AC Tien, M Acar, HJ Bellen Oxford University Press for The Company of Biologists Limited 133 (9), 1683-1692, 2006 | 77 | 2006 |
A phase 0 trial of ribociclib in recurrent glioblastoma patients incorporating a tumor pharmacodynamic-and pharmacokinetic-guided expansion cohort AC Tien, J Li, X Bao, A Derogatis, S Kim, S Mehta, N Sanai Clinical Cancer Research 25 (19), 5777-5786, 2019 | 54 | 2019 |
Lineage-restricted OLIG2-RTK signaling governs the molecular subtype of glioma stem-like cells R Kupp, L Shtayer, AC Tien, E Szeto, N Sanai, DH Rowitch, S Mehta Cell reports 16 (11), 2838-2845, 2016 | 53 | 2016 |
Identification of the substrates and interaction proteins of aurora kinases from a protein-protein interaction model AC Tien, MH Lin, LJ Su, YR Hong, TS Cheng, YCG Lee, WJ Lin, IH Still, ... Molecular & Cellular Proteomics 3 (1), 93-104, 2004 | 50 | 2004 |
Negative-feedback regulation of proneural proteins controls the timing of neural precursor division PJ Chang, YL Hsiao, AC Tien, YC Li, H Pi Oxford University Press for The Company of Biologists Limited 135 (18), 3021 …, 2008 | 44 | 2008 |
Caspase 3, periodically expressed and activated at G2/M transition, is required for nocodazole-induced mitotic checkpoint SL Hsu, CTR Yu, SC Yin, MJ Tang, AC Tien, YM Wu, CYF Huang Apoptosis 11, 765-771, 2006 | 40 | 2006 |
Rich regulates target specificity of photoreceptor cells and N-cadherin trafficking in the Drosophila visual system via Rab6 C Tong, T Ohyama, AC Tien, A Rajan, CM Haueter, HJ Bellen Neuron 71 (3), 447-459, 2011 | 36 | 2011 |
A sequentially priming phosphorylation cascade activates the gliomagenic transcription factor Olig2 J Zhou, AC Tien, JA Alberta, SB Ficarro, A Griveau, Y Sun, JS Deshpande, ... Cell reports 18 (13), 3167-3177, 2017 | 35 | 2017 |
Dynamic expression and cellular localization of the Drosophila 14-3-3ϵ during embryonic development AC Tien, HY Hsei, CT Chien Mechanisms of development 81 (1-2), 209-212, 1999 | 33 | 1999 |