Associate Professor Boon Chuan LOW
Associate Professor Boon Chuan LOW
The National University of Singapore and Mechanobiology Institute Singapore
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YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth
BC Low, CQ Pan, GV Shivashankar, A Bershadsky, M Sudol, M Sheetz
FEBS letters 588 (16), 2663-2670, 2014
Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling
ESM Wong, CW Fong, J Lim, P Yusoff, BC Low, WY Langdon, GR Guy
The EMBO journal 21 (18), 4796-4808, 2002
Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism
K Thangavelu, CQ Pan, T Karlberg, G Balaji, M Uttamchandani, V Suresh, ...
Proceedings of the National Academy of Sciences 109 (20), 7705-7710, 2012
Evidence for direct interaction between Sprouty and Cbl
ESM Wong, J Lim, BC Low, Q Chen, GR Guy
Journal of Biological Chemistry 276 (8), 5866-5875, 2001
Cortactin phosphorylation as a switch for actin cytoskeletal network and cell dynamics control
BL Lua, BC Low
FEBS letters 579 (3), 577-585, 2005
In-Silico approaches to multi-target drug discovery
XH Ma, Z Shi, C Tan, Y Jiang, ML Go, BC Low, YZ Chen
Pharmaceutical research 27 (5), 739-749, 2010
RhoA acts downstream of Wnt5 and Wnt11 to regulate convergence and extension movements by involving effectors Rho kinase and Diaphanous: use of zebrafish as an in vivo model …
S Zhu, L Liu, V Korzh, Z Gong, BC Low
Cellular signalling 18 (3), 359-372, 2006
Sprouty Proteins Are Targeted to Membrane Ruffles upon Growth Factor Receptor Tyrosine Kinase Activation IDENTIFICATION OF A NOVEL TRANSLOCATION DOMAIN
J Lim, ESM Wong, SH Ong, P Yusoff, BC Low, GR Guy
Journal of Biological Chemistry 275 (42), 32837-32845, 2000
A genetic pathway composed of Sox14 and Mical governs severing of dendrites during pruning
D Kirilly, Y Gu, Y Huang, Z Wu, A Bashirullah, BC Low, AL Kolodkin, ...
Nature neuroscience 12 (12), 1497-1505, 2009
A Cdo–Bnip-2–Cdc42 signaling pathway regulates p38α/β MAPK activity and myogenic differentiation
JS Kang, GU Bae, MJ Yi, YJ Yang, JE Oh, G Takaesu, YT Zhou, BC Low, ...
The Journal of cell biology 182 (3), 497-507, 2008
YAP regulates actin dynamics through ARHGAP29 and promotes metastasis
Y Qiao, J Chen, YB Lim, ML Finch-Edmondson, VP Seshachalam, L Qin, ...
Cell reports 19 (8), 1495-1502, 2017
Interleukin-1 and tumor necrosis factor-stimulate the cat-2 gene of the L-arginine transporter in cultured vascular smooth muscle cells
DJ Gill, BC Low, MR Grigor
Journal of Biological Chemistry 271 (19), 11280-11283, 1996
Modularity and functional plasticity of scaffold proteins as p (l) acemakers in cell signaling
CQ Pan, M Sudol, M Sheetz, BC Low
Cellular signalling 24 (11), 2143-2165, 2012
Crosstalk of Ras and Rho: activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models
TW Chew, XJ Liu, L Liu, JM Spitsbergen, Z Gong, BC Low
Oncogene 33 (21), 2717-2727, 2014
SHP2 associates directly with tyrosine phosphorylated p90 (SNT) protein in FGF-stimulated cells
SH Ong, YP Lim, BC Low, GR Guy
Biochemical and biophysical research communications 238 (1), 261-266, 1997
The SAM domain of the RhoGAP DLC1 binds EF1A1 to regulate cell migration
D Zhong, J Zhang, S Yang, UJK Soh, JP Buschdorf, YT Zhou, D Yang, ...
Journal of cell science 122 (3), 414-424, 2009
K-ras/PI3K-Akt signaling is essential for zebrafish hematopoiesis and angiogenesis
L Liu, S Zhu, Z Gong, BC Low
PLoS One 3 (8), e2850, 2008
Brain-specific BNIP-2-homology protein Caytaxin relocalises glutaminase to neurite terminals and reduces glutamate levels
JP Buschdorf, LL Chew, B Zhang, Q Cao, FY Liang, YC Liou, YT Zhou, ...
Journal of cell science 119 (16), 3337-3350, 2006
Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA)
K Thangavelu, QY Chong, BC Low, J Sivaraman
Scientific reports 4, 3827, 2014
Virtual screening of selective multitarget kinase inhibitors by combinatorial support vector machines
XH Ma, R Wang, CY Tan, YY Jiang, T Lu, HB Rao, XY Li, ML Go, BC Low, ...
Molecular pharmaceutics 7 (5), 1545-1560, 2010
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