| Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response G Chen, AC Huang, W Zhang, G Zhang, M Wu, W Xu, Z Yu, J Yang, ... Nature 560 (7718), 382-386, 2018 | 2066 | 2018 |
| A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma AC Huang, RJ Orlowski, X Xu, R Mick, SM George, PK Yan, S Manne, ... Nature medicine 25 (3), 454-461, 2019 | 547 | 2019 |
| Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation SM Kumar, S Liu, H Lu, H Zhang, PJ Zhang, PA Gimotty, M Guerra, W Guo, ... Oncogene 31 (47), 4898-4911, 2012 | 381 | 2012 |
| Melittin prevents liver cancer cell metastasis through inhibition of the Rac1‐dependent pathway S Liu, M Yu, Y He, L Xiao, F Wang, C Song, S Sun, C Ling, Z Xu Hepatology 47 (6), 1964-1973, 2008 | 257 | 2008 |
| miR-200c inhibits melanoma progression and drug resistance through down-regulation of BMI-1 S Liu, MT Tetzlaff, R Cui, X Xu The American journal of pathology 181 (5), 1823-1835, 2012 | 198 | 2012 |
| MicroRNA‐9 up‐regulates E‐cadherin through inhibition of NF‐κB1–Snail1 pathway in melanoma S Liu, SM Kumar, H Lu, A Liu, R Yang, A Pushparajan, W Guo, X Xu The Journal of pathology 226 (1), 61-72, 2012 | 190 | 2012 |
| A unified approach to targeting the lysosome's degradative and growth signaling roles VW Rebecca, MC Nicastri, N McLaughlin, C Fennelly, Q McAfee, ... Cancer discovery 7 (11), 1266-1283, 2017 | 162 | 2017 |
| PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas Nature, 2017 | 160 | 2017 |
| Generation of folliculogenic human epithelial stem cells from induced pluripotent stem cells R Yang, Y Zheng, M Burrows, S Liu, Z Wei, A Nace, W Guo, S Kumar, ... Nature communications 5 (1), 3071, 2014 | 122 | 2014 |
| Loss of microRNA-205 expression is associated with melanoma progression S Liu, MT Tetzlaff, A Liu, B Liegl-Atzwanger, J Guo, X Xu Laboratory investigation 92 (7), 1084-1096, 2012 | 92 | 2012 |
| Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors R Yang, Y Zheng, L Li, S Liu, M Burrows, Z Wei, A Nace, M Herlyn, R Cui, ... Nature communications 5 (1), 5807, 2014 | 81 | 2014 |
| A slow-cycling subpopulation of melanoma cells with highly invasive properties M Perego, M Maurer, JX Wang, S Shaffer, AC Müller, K Parapatics, L Li, ... Oncogene 37 (3), 302-312, 2018 | 76 | 2018 |
| ER translocation of the MAPK pathway drives therapy resistance in BRAF-mutant melanoma R Ojha, NM Leli, A Onorati, S Piao, II Verginadis, F Tameire, VW Rebecca, ... Cancer discovery 9 (3), 396-415, 2019 | 73 | 2019 |
| Exo70 Isoform Switching upon Epithelial-Mesenchymal Transition Mediates Cancer Cell Invasion GW Lu H, Liu J, Liu S, Zeng J, Ding D, Carstens RP, Cong Y, Xu X Dev Cell 27, 560-73, 2013 | 68 | 2013 |
| Large-scale Analysis of PDGFRA Mutations in Melanomas and Evaluation of Their Sensitivity to Tyrosine Kinase Inhibitors Imatinib and Crenolanib J Dai, Y Kong, L Si, Z Chi, C Cui, X Sheng, L Mao, S Li, B Lian, R Yang, ... Clinical Cancer Research 19 (24), 6935-6942, 2013 | 63 | 2013 |
| The FBXO4 tumor suppressor functions as a barrier to BrafV600E3 dependent metastatic melanoma Mol Cell Biol. 33, 4422–4433, 2013 | 63 | 2013 |
| Oncogenic BRAF-mediated melanoma cell invasion H Lu, S Liu, G Zhang, LN Kwong, Y Zhu, JP Miller, Y Hu, W Zhong, J Zeng, ... Cell reports 15 (9), 2012-2024, 2016 | 59 | 2016 |
| IL8 and cathepsin B as melanoma serum biomarkers H Zhang, T Fu, S McGettigan, S Kumar, S Liu, D Speicher, L Schuchter, ... International journal of molecular sciences 12 (3), 1505-1518, 2011 | 56 | 2011 |
| PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma G Sharma, R Ojha, E Noguera-Ortega, VW Rebecca, J Attanasio, S Liu, ... JCI insight 5 (17), 2020 | 53 | 2020 |
| Downregulated NM23-H1 expression is associated with intracranial invasion of nasopharyngeal carcinoma SJ Liu, YM Sun, DF Tian, YC He, L Zeng, Y He, CQ Ling, SH Sun British journal of cancer 98 (2), 363-369, 2008 | 53 | 2008 |
Xiaowei XuProfessor at University of Pennsylvania, Departments of Pathology and DermatologyVerified email at pennmedicine.upenn.edu
