Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines. E Gurgul, S Lortz, M Tiedge, A Jörns, S Lenzen Diabetes 53 (9), 2271-80, 2004 | 167 | 2004 |
Interaction between pro-inflammatory and anti-inflammatory cytokines in insulin-producing cells KLA Souza, E Gurgul-Convey, M Elsner, S Lenzen Journal of Endocrinology 197 (1), 139-150, 2008 | 113 | 2008 |
Relative importance of cellular uptake and reactive oxygen species for the toxicity of alloxan and dialuric acid to insulin-producing cells M Elsner, E Gurgul-Convey, S Lenzen Free radical biology and medicine 41 (5), 825-834, 2006 | 111 | 2006 |
Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria E Gurgul-Convey, I Mehmeti, S Lortz, S Lenzen Journal of molecular medicine 89, 785-798, 2011 | 92 | 2011 |
Sensitivity profile of the human EndoC-βH1 beta cell line to proinflammatory cytokines E Gurgul-Convey, I Mehmeti, T Plötz, A Jörns, S Lenzen Diabetologia 59, 2125-2133, 2016 | 70 | 2016 |
Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreich's ataxia M Igoillo-Esteve, E Gurgul-Convey, A Hu, ... Human molecular genetics 24 (8), 2274-2286, 2015 | 70 | 2015 |
Importance of mitochondrial superoxide dismutase expression in insulin-producing cells for the toxicity of reactive oxygen species and proinflammatory cytokines S Lortz, E Gurgul-Convey, S Lenzen, M Tiedge Diabetologia 48, 1541-1548, 2005 | 67 | 2005 |
Differential effects of proinflammatory cytokines on cell death and ER stress in insulin-secreting INS1E cells and the involvement of nitric oxide S Kacheva, S Lenzen, E Gurgul-Convey Cytokine 55 (2), 195-201, 2011 | 61 | 2011 |
Progesterone induces apoptosis of insulin-secreting cells: insights into the molecular mechanism VA Nunes, EP Portioli-Sanches, MP Rosim, MS Araujo, ... J Endocrinol 221 (2), 273-284, 2014 | 56 | 2014 |
Overexpression of the antioxidant enzyme catalase does not interfere with the glucose responsiveness of insulin-secreting INS-1E cells and rat islets S Lortz, E Gurgul-Convey, O Naujok, S Lenzen Diabetologia 56 (4), 774-782, 2013 | 50 | 2013 |
Induction of the intrinsic apoptosis pathway in insulin-secreting cells is dependent on oxidative damage of mitochondria but independent of caspase-12 activation I Mehmeti, E Gurgul-Convey, S Lenzen, S Lortz Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (10), 1827-1835, 2011 | 50 | 2011 |
Physiological characterization of the human EndoC-βH1 β-cell line E Gurgul-Convey, MT Kaminski, S Lenzen Biochemical and biophysical research communications 464 (1), 13-19, 2015 | 48 | 2015 |
Protection of insulin-producing cells against toxicity of dexamethasone by catalase overexpression LP Roma, JR Bosqueiro, DA Cunha, EM Carneiro, E Gurgul-Convey, ... Free Radical Biology and Medicine 47 (10), 1386-1393, 2009 | 33 | 2009 |
Protection against cytokine toxicity through endoplasmic reticulum and mitochondrial stress prevention by prostacyclin synthase overexpression in insulin-producing cells E Gurgul-Convey, S Lenzen Journal of biological chemistry 285 (15), 11121-11128, 2010 | 32 | 2010 |
Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity C Hahn, K Tyka, JD Saba, S Lenzen, E Gurgul-Convey Journal of Biological Chemistry 292 (49), 20292-20304, 2017 | 27 | 2017 |
Mechanism of prostacyclin-induced potentiation of glucose-induced insulin secretion E Gurgul-Convey, K Hanzelka, S Lenzen Endocrinology 153 (6), 2612-2622, 2012 | 24 | 2012 |
Relation between triketone structure, generation of reactive oxygen species, and selective toxicity of the diabetogenic agent alloxan M Elsner, E Gurgul-Convey, S Lenzen Antioxidants & Redox Signaling 10 (4), 691-700, 2008 | 24 | 2008 |
Enhancement of homocysteine toxicity to insulin-secreting BRIN-BD11 cells in combination with alloxan SMJ Scullion, E Gurgul-Convey, M Elsner, S Lenzen, PR Flatt, ... Journal of endocrinology 214 (2), 233, 2012 | 20 | 2012 |
IL-1β hampers glucose-stimulated insulin secretion in Cohen diabetic rat islets through mitochondrial cytochrome c oxidase inhibition by nitric oxide S Weksler-Zangen, G Aharon-Hananel, C Mantzur, T Aouizerat, ... American Journal of Physiology-Endocrinology and Metabolism 306 (6), E648-E657, 2014 | 18 | 2014 |
Is there a role for neuronal nitric oxide synthase (nNOS) in cytokine toxicity to pancreatic beta cells? E Gurgul-Convey, K Hanzelka, S Lenzen Nitric Oxide 27 (4), 235-241, 2012 | 16 | 2012 |