The selectivity of inhibitors of protein kinase CK2: an update MA Pagano, J Bain, Z Kazimierczuk, S Sarno, M Ruzzene, G Di Maira, ... Biochemical Journal 415 (3), 353-365, 2008 | 279 | 2008 |
Optimization of protein kinase CK2 inhibitors derived from 4, 5, 6, 7-tetrabromobenzimidazole MA Pagano, M Andrzejewska, M Ruzzene, S Sarno, L Cesaro, J Bain, ... Journal of medicinal chemistry 47 (25), 6239-6247, 2004 | 222 | 2004 |
2-Dimethylamino-4, 5, 6, 7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2 MA Pagano, F Meggio, M Ruzzene, M Andrzejewska, Z Kazimierczuk, ... Biochemical and biophysical research communications 321 (4), 1040-1044, 2004 | 221 | 2004 |
Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application G Cozza, P Bonvini, E Zorzi, G Poletto, MA Pagano, S Sarno, ... Journal of medicinal chemistry 49 (8), 2363-2366, 2006 | 188 | 2006 |
Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2 G Cozza, M Mazzorana, E Papinutto, J Bain, M Elliott, G Di Maira, ... Biochemical Journal 421 (3), 387-395, 2009 | 186 | 2009 |
A noncanonical sequence phosphorylated by casein kinase 1 in β-catenin may play a role in casein kinase 1 targeting of important signaling proteins O Marin, VH Bustos, L Cesaro, F Meggio, MA Pagano, M Antonelli, ... Proceedings of the National Academy of Sciences 100 (18), 10193-10200, 2003 | 182 | 2003 |
Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5, 6-dihydroindolo-(1, 2-a) quinazolin-7-yl] acetic acid (IQA) S Sarno, E de Moliner, M Ruzzene, MA Pagano, R Battistutta, J Bain, ... Biochemical journal 374 (3), 639-646, 2003 | 170 | 2003 |
Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors MA Pagano, G Poletto, G Di Maira, G Cozza, M Ruzzene, S Sarno, J Bain, ... Chembiochem 8 (1), 129-139, 2007 | 139 | 2007 |
Aurora-A site specificity: a study with synthetic peptide substrates S Ferrari, O Marin, MA Pagano, F Meggio, D Hess, M El-Shemerly, ... Biochemical Journal 390 (1), 293-302, 2005 | 136 | 2005 |
Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study F Meggio, MA Pagano, S Moro, G Zagotto, M Ruzzene, S Sarno, G Cozza, ... Biochemistry 43 (40), 12931-12936, 2004 | 115 | 2004 |
Development and exploitation of CK2 inhibitors S Sarno, M Ruzzene, P Frascella, MA Pagano, F Meggio, A Zambon, ... Molecular and cellular biochemistry 274, 69-76, 2005 | 110 | 2005 |
Tyrosine Versus Serine/Threonine Phosphorylation by Protein Kinase Casein Kinase-2: A STUDY WITH PEPTIDE SUBSTRATES DERIVED FROM IMMUNOPHILIN Fpr3 O Marin, F Meggio, S Sarno, L Cesaro, MA Pagano, LA Pinna Journal of Biological Chemistry 274 (41), 29260-29265, 1999 | 88 | 1999 |
Protein kinase CK2: a newcomer in the ‘druggable kinome’ MA Pagano, L Cesaro, F Meggio, LA Pinna Biochemical Society Transactions 34 (6), 1303-1306, 2006 | 87 | 2006 |
Polyhalogenobenzimidazoles: synthesis and their inhibitory activity against casein kinases M Andrzejewska, MA Pagano, F Meggio, AM Brunati, Z Kazimierczuk Bioorganic & medicinal chemistry 11 (18), 3997-4002, 2003 | 78 | 2003 |
Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia L Trentin, M Frasson, A Donella-Deana, F Frezzato, MA Pagano, E Tibaldi, ... Blood, The Journal of the American Society of Hematology 112 (12), 4665-4674, 2008 | 76 | 2008 |
Unique features of HIV-1 Rev protein phosphorylation by protein kinase CK2 (‘casein kinase-2’) O Marin, S Sarno, M Boschetti, MA Pagano, F Meggio, V Ciminale, ... FEBS letters 481 (1), 63-67, 2000 | 65 | 2000 |
The regulatory β subunit of protein kinase CK2 contributes to the recognition of the substrate consensus sequence. A study with an eIF2β-derived peptide G Poletto, J Vilardell, O Marin, MA Pagano, G Cozza, S Sarno, A Falqués, ... Biochemistry 47 (32), 8317-8325, 2008 | 57 | 2008 |
Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A F Zonta, MA Pagano, L Trentin, E Tibaldi, F Frezzato, V Trimarco, M Facco, ... Blood, The Journal of the American Society of Hematology 125 (24), 3747-3755, 2015 | 55 | 2015 |
Thiol redox systems and protein kinases in hepatic stellate cell regulatory processes AM Brunati, MA Pagano, A Bindoli, MP Rigobello Free Radical Research 44 (4), 363-378, 2010 | 49 | 2010 |
Autophosphorylation at the regulatory β subunit reflects the supramolecular organization of protein kinase CK2 MA Pagano, S Sarno, G Poletto, G Cozza, LA Pinna, F Meggio Molecular and cellular biochemistry 274, 23-29, 2005 | 49 | 2005 |