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Lawrence T Wang
Lawrence T Wang
MD-DPhil student at UC San Diego and NIH-Oxford Scholars Program
Verified email at health.ucsd.edu
Title
Cited by
Cited by
Year
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics
AN Cowell, ES Istvan, AK Lukens, MG Gomez-Lorenzo, M Vanaerschot, ...
Science 359 (6372), 191-199, 2018
2182018
A potent anti-malarial human monoclonal antibody targets circumsporozoite protein minor repeats and neutralizes sporozoites in the liver
LT Wang, LS Pereira, Y Flores-Garcia, J O’Connor, BJ Flynn, A Schön, ...
Immunity 53 (4), 733-744. e8, 2020
1072020
Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity
GM LaMonte, J Almaliti, B Bibo-Verdugo, L Keller, BY Zou, J Yang, ...
Journal of medicinal chemistry 60 (15), 6721-6732, 2017
812017
Low-dose subcutaneous or intravenous monoclonal antibody to prevent malaria
RL Wu, AH Idris, NM Berkowitz, M Happe, MR Gaudinski, C Buettner, ...
New England Journal of Medicine 387 (5), 397-407, 2022
692022
Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection
GM LaMonte, P Orjuela-Sanchez, J Calla, LT Wang, S Li, J Swann, ...
Nature communications 10 (1), 488, 2019
452019
The P. falciparum CSP repeat region contains three distinct epitopes required for protection by antibodies in vivo
Y Flores-Garcia, LT Wang, M Park, B Asady, AH Idris, NK Kisalu, C Muñoz, ...
PLoS pathogens 17 (11), e1010042, 2021
242021
Functional human IgA targets a conserved site on malaria sporozoites
J Tan, H Cho, T Pholcharee, LS Pereira, S Doumbo, D Doumtabe, ...
Science translational medicine 13 (599), eabg2344, 2021
242021
Private sector drug shops frequently dispense parenteral anti-malarials in a rural region of Western Uganda
LT Wang, R Bwambale, C Keeler, R Reyes, R Muhindo, M Matte, M Ntaro, ...
Malaria journal 17, 1-9, 2018
242018
Protective effects of combining monoclonal antibodies and vaccines against the Plasmodium falciparum circumsporozoite protein
LT Wang, LS Pereira, PK Kiyuka, A Schön, NK Kisalu, R Vistein, M Dillon, ...
PLoS pathogens 17 (12), e1010133, 2021
232021
Prevalence of baseline polymorphisms for potential resistance to NS5A inhibitors in drug-naive individuals infected with hepatitis C genotypes 1–4
AL McCormick, L Wang, A Garcia-Diaz, MJ Macartney, DP Webster, ...
Antiviral therapy 20 (1), 81-85, 2015
232015
Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies
S Kratochvil, CH Shen, YC Lin, K Xu, U Nair, LDS Pereira, P Tripathi, ...
Immunity 54 (12), 2859-2876. e7, 2021
212021
Schö n
LT Wang, LS Pereira, Y Flores-Garcia, J O’Connor, BJ Flynn
A., Hurlburt, NK, Dillon, M., Yang, ASP, Fabra-Garcıa, A., et al, 733-744, 2020
192020
Design of alphavirus virus-like particles presenting circumsporozoite junctional epitopes that elicit protection against malaria
JR Francica, W Shi, GY Chuang, SJ Chen, L Da Silva Pereira, SK Farney, ...
Vaccines 9 (3), 272, 2021
142021
The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria
LT Wang, NK Hurlburt, A Schön, BJ Flynn, Y Flores-Garcia, LS Pereira, ...
Cell reports 38 (7), 2022
132022
Superior antibody immunogenicity of a viral-vectored RH5 blood-stage malaria vaccine in Tanzanian infants as compared to adults
SE Silk, WF Kalinga, IM Mtaka, NS Lilolime, M Mpina, F Milando, ...
Med 4 (10), 668-686. e7, 2023
92023
Antigenic Restimulation of Virus-Specific Memory CD8+ T Cells Requires Days of Lytic Protein Accumulation for Maximal Cytotoxic Capacity
SA Migueles, DC Rogan, NV Gavil, EP Kelly, SA Toulmin, LT Wang, ...
Journal of Virology 94 (23), 10.1128/jvi. 01595-20, 2020
92020
Aggregative adherence and intestinal colonization by enteroaggregative Escherichia coli are produced by interactions among multiple surface factors
LV Blanton, LT Wang, J Hofmann, J DuBow, A Lafrance, S Kwak, ...
Msphere 3 (2), 10.1128/msphere. 00078-18, 2018
92018
Cytotoxicity of human antibodies targeting the circumsporozoite protein is amplified by 3D substrate and correlates with protection
MC Aguirre-Botero, LT Wang, P Formaglio, E Aliprandini, JM Thiberge, ...
Cell reports 42 (7), 2023
52023
HIV vaccines induce CD8+ T cells with low antigen receptor sensitivity
SA Migueles, DM Nettere, NV Gavil, LT Wang, SA Toulmin, EP Kelly, ...
Science 382 (6676), 1270-1276, 2023
22023
Cryo-EM structures of anti-malarial antibody L9 with circumsporozoite protein reveal trimeric L9 association and complete 27-residue epitope
P Tripathi, MF Bender, H Lei, LDS Pereira, CH Shen, B Bonilla, M Dillon, ...
Structure 31 (4), 480-491. e4, 2023
22023
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