The mTORC1 signaling network senses changes in cellular purine nucleotide levels G Hoxhaj, J Hughes-Hallett, RC Timson, E Ilagan, M Yuan, JM Asara, ... Cell reports 21 (5), 1331-1346, 2017 | 176 | 2017 |
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation RA Weber, FS Yen, SPV Nicholson, H Alwaseem, EC Bayraktar, M Alam, ... Molecular cell 77 (3), 645-655. e7, 2020 | 171 | 2020 |
Quick generation of R aman spectroscopy based in‐process glucose control to influence biopharmaceutical protein product quality during mammalian cell culture BN Berry, TM Dobrowsky, RC Timson, R Kshirsagar, T Ryll, K Wiltberger Biotechnology Progress 32 (1), 224-234, 2016 | 137 | 2016 |
SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells Y Wang, FS Yen, XG Zhu, RC Timson, R Weber, C Xing, Y Liu, B Allwein, ... Nature 599 (7883), 136-140, 2021 | 120 | 2021 |
Direct stimulation of NADP+ synthesis through Akt-mediated phosphorylation of NAD kinase G Hoxhaj, I Ben-Sahra, SE Lockwood, RC Timson, V Byles, GT Henning, ... Science 363 (6431), 1088-1092, 2019 | 103 | 2019 |
Functional genomics in vivo reveal metabolic dependencies of pancreatic cancer cells XG Zhu, A Chudnovskiy, L Baudrier, B Prizer, Y Liu, BN Ostendorf, ... Cell metabolism 33 (1), 211-221. e6, 2021 | 78 | 2021 |
Identification of the dimer exchange Interface of the bacterial DNA damage response protein UmuD DA Murison, RC Timson, BN Koleva, M Ordazzo, PJ Beuning Biochemistry 56 (36), 4773-4785, 2017 | 4 | 2017 |
Development of a mouse model expressing a bifunctional glutathione-synthesizing enzyme to study glutathione limitation in vivo RC Timson, A Khan, B Uygur, M Saad, HW Yeh, NL DelGaudio, R Weber, ... Journal of Biological Chemistry 300 (2), 2024 | 2 | 2024 |
A mouse model to study glutathione limitation in vivo RC Timson, A Khan, B Uygur, M Saad, HW Yeh, NL DelGaudio, R Weber, ... bioRxiv, 2024.01. 08.574722, 2024 | | 2024 |