Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer R Nilsson, M Jain, N Madhusudhan, NG Sheppard, L Strittmatter, C Kampf, ... Nature communications 5 (1), 3128, 2014 | 576 | 2014 |
Inactivation of liver X receptor β leads to adult-onset motor neuron degeneration in male mice S Andersson, N Gustafsson, M Warner, JÅ Gustafsson Proceedings of the National Academy of Sciences 102 (10), 3857-3862, 2005 | 190 | 2005 |
NUDT15 hydrolyzes 6-thio-deoxyGTP to mediate the anticancer efficacy of 6-thioguanine NCK Valerie, A Hagenkort, BDG Page, G Masuyer, D Rehling, M Carter, ... Cancer research 76 (18), 5501-5511, 2016 | 109 | 2016 |
The folate-coupled enzyme MTHFD2 is a nuclear protein and promotes cell proliferation N Gustafsson Sheppard, L Jarl, D Mahadessian, L Strittmatter, A Schmidt, ... Scientific reports 5 (1), 15029, 2015 | 104 | 2015 |
Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination NMS Gustafsson, K Färnegårdh, N Bonagas, AH Ninou, P Groth, E Wiita, ... Nature communications 9 (1), 3872, 2018 | 103 | 2018 |
Crystal structure of the emerging cancer target MTHFD2 in complex with a substrate-based inhibitor R Gustafsson, AS Jemth, NMS Gustafsson, K Färnegårdh, O Loseva, ... Cancer research 77 (4), 937-948, 2017 | 78 | 2017 |
RBCK1 drives breast cancer cell proliferation by promoting transcription of estrogen receptor α and cyclin B1 N Gustafsson, C Zhao, JÅ Gustafsson, K Dahlman-Wright Cancer research 70 (3), 1265-1274, 2010 | 66 | 2010 |
E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesis A Ehrlund, EH Anthonisen, N Gustafsson, N Venteclef, ... Molecular and cellular biology 29 (8), 2230-2242, 2009 | 57 | 2009 |
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress N Bonagas, NMS Gustafsson, M Henriksson, P Marttila, R Gustafsson, ... Nature cancer 3 (2), 156-172, 2022 | 34 | 2022 |
Estrogen receptor-a, RBCK1, and protein kinase C b 1 cooperate to regulate estrogen receptor-a gene expression NG Sheppard, N Heldring, K Dahlman-Wright Journal of molecular endocrinology 49, 277-287, 2012 | 15 | 2012 |
Distinct mechanistic responses to replication fork stalling induced by either nucleotide or protein deprivation S Henriksson, P Groth, N Gustafsson, T Helleday Cell Cycle 17 (5), 568-579, 2018 | 12 | 2018 |
The γ-tubulin meshwork assists in the recruitment of PCNA to chromatin in mammalian cells M Corvaisier, J Zhou, D Malycheva, N Cornella, D Chioureas, ... Communications Biology 4 (1), 767, 2021 | 11 | 2021 |
PFKFB3 inhibition sensitizes DNA crosslinking chemotherapies by suppressing Fanconi anemia repair AH Ninou, J Lehto, D Chioureas, H Stigsdotter, K Schelzig, E Åkerlund, ... Cancers 13 (14), 3604, 2021 | 8 | 2021 |
Targeting cx3cr1 suppresses the fanconi anemia dna repair pathway and synergizes with platinum J Lehto, A Huguet Ninou, D Chioureas, J Jonkers, NMS Gustafsson Cancers 13 (6), 1442, 2021 | 8 | 2021 |
Molecular characterization of estrogen receptor signaling in breast cancer cells C Zhao, H Gao, N Gustafsson, Z Papoutsi, S Jaffrey, JA Gustafsson, ... FEBS JOURNAL 277, 10-10, 2010 | | 2010 |
Inactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male mice (vol 102, pg 3857, 2005) S Andersson, N Gustafsson, M Warner, JA Gustafsson PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF …, 2006 | | 2006 |
Inactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male mice S Andersson, N Gustafsson, M Warner, J Gustafsson PROCEEDINGS-NATIONAL ACADEMY OF SCIENCES USA 103 (21), 8298, 2006 | | 2006 |