Structural insight into substrate preference for TET-mediated oxidation L Hu, J Lu, J Cheng, Q Rao, Z Li, H Hou, Z Lou, L Zhang, W Li, W Gong, ... Nature 527 (7576), 118-122, 2015 | 287 | 2015 |
Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies X Zhu, D Mannar, SS Srivastava, AM Berezuk, JP Demers, JW Saville, ... PLoS biology 19 (4), e3001237, 2021 | 178 | 2021 |
Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody T Ying, P Prabakaran, L Du, W Shi, Y Feng, Y Wang, L Wang, W Li, ... Nature communications 6 (1), 8223, 2015 | 124 | 2015 |
High potency of a bivalent human VH domain in SARS-CoV-2 animal models W Li, A Schäfer, SS Kulkarni, X Liu, DR Martinez, C Chen, Z Sun, SR Leist, ... Cell 183 (2), 429-441. e16, 2020 | 123 | 2020 |
Antibody aggregation: insights from sequence and structure W Li, P Prabakaran, W Chen, Z Zhu, Y Feng, DS Dimitrov Antibodies 5 (3), 19, 2016 | 122 | 2016 |
RETRACTED ARTICLE: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs M Yarmarkovich, QF Marshall, JM Warrington, R Premaratne, A Farrel, ... Nature 599 (7885), 477-484, 2021 | 95 | 2021 |
Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection W Li, C Chen, A Drelich, DR Martinez, LE Gralinski, Z Sun, A Schäfer, ... Proceedings of the National Academy of Sciences 117 (47), 29832-29838, 2020 | 88 | 2020 |
Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants JW Saville, D Mannar, X Zhu, SS Srivastava, AM Berezuk, JP Demers, ... Nature communications 13 (1), 742, 2022 | 76 | 2022 |
Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding D Mannar, JW Saville, X Zhu, SS Srivastava, AM Berezuk, S Zhou, ... Cell reports 37 (12), 2021 | 75 | 2021 |
Crystallizable fragment glycoengineering for therapeutic antibodies development W Li, Z Zhu, W Chen, Y Feng, DS Dimitrov Frontiers in immunology 8, 1554, 2017 | 75 | 2017 |
Potent neutralization of SARS-CoV-2 by human antibody heavy-chain variable domains isolated from a large library with a new stable scaffold Z Sun, C Chen, W Li, DR Martinez, A Drelich, DS Baek, X Liu, JW Mellors, ... MAbs 12 (1), 1778435, 2020 | 63 | 2020 |
Proteomic screens for suppressors of anoikis identify IL1RAP as a promising surface target in Ewing sarcoma HF Zhang, CS Hughes, W Li, JZ He, D Surdez, AM El-Naggar, H Cheng, ... Cancer discovery 11 (11), 2884-2903, 2021 | 53 | 2021 |
A potent germline-like human monoclonal antibody targets a pH-sensitive epitope on H7N9 influenza hemagglutinin F Yu, H Song, Y Wu, SY Chang, L Wang, W Li, B Hong, S Xia, C Wang, ... Cell host & microbe 22 (4), 471-483. e5, 2017 | 47 | 2017 |
Discovery of T-cell infection and apoptosis by Middle East respiratory syndrome coronavirus T Ying, W Li, DS Dimitrov The Journal of infectious diseases 213 (6), 877-879, 2016 | 44 | 2016 |
Potent In Vivo NK Cell-Mediated Elimination of HIV-1-Infected Cells Mobilized by a gp120-Bispecific and Hexavalent Broadly Neutralizing Fusion Protein A Bardhi, Y Wu, W Chen, W Li, Z Zhu, JH Zheng, H Wong, E Jeng, J Jones, ... Journal of virology 91 (20), 10.1128/jvi. 00937-17, 2017 | 43 | 2017 |
A Novel Tyrosine–Heme C O Covalent Linkage in F43Y Myoglobin: A New Post‐translational Modification of Heme Proteins DJ Yan, W Li, Y Xiang, GB Wen, YW Lin, X Tan ChemBioChem 16 (1), 47-50, 2015 | 41 | 2015 |
SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization D Mannar, JW Saville, Z Sun, X Zhu, MM Marti, SS Srivastava, ... Nature Communications 13 (1), 4696, 2022 | 39 | 2022 |
Exploring the differences between mouse mAβ 1–42 and human hAβ 1–42 for Alzheimer's disease related properties and neuronal cytotoxicity X Lv, W Li, Y Luo, D Wang, C Zhu, ZX Huang, X Tan Chemical Communications 49 (52), 5865-5867, 2013 | 37 | 2013 |
Enhanced elicitation of potent neutralizing antibodies by the SARS-CoV-2 spike receptor binding domain Fc fusion protein in mice X Liu, A Drelich, W Li, C Chen, Z Sun, M Shi, C Adams, JW Mellors, ... Vaccine 38 (46), 7205-7212, 2020 | 33 | 2020 |
A broadly neutralizing germline-like human monoclonal antibody against dengue virus envelope domain III D Hu, Z Zhu, S Li, Y Deng, Y Wu, N Zhang, V Puri, C Wang, P Zou, C Lei, ... PLoS pathogens 15 (6), e1007836, 2019 | 33 | 2019 |