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Shabnam Davoodi
Shabnam Davoodi
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Year
Evaluating the contribution of transition-state destabilization to changes in the residence time of triazole-based InhA inhibitors
LA Spagnuolo, S Eltschkner, W Yu, F Daryaee, S Davoodi, SE Knudson, ...
Journal of the American Chemical Society 139 (9), 3417-3429, 2017
522017
Correlating Drug–Target Residence Time and Post-antibiotic Effect: Insight into Target Vulnerability
S Davoodi, F Daryaee, A Chang, SG Walker, PJ Tonge
ACS infectious diseases 6 (4), 629-636, 2020
202020
Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase
C Neckles, A Pschibul, CT Lai, M Hirschbeck, J Kuper, S Davoodi, J Zou, ...
Biochemistry 55 (21), 2992-3006, 2016
102016
Rationalizing the Binding Kinetics for the Inhibition of the Burkholderia pseudomallei FabI1 Enoyl-ACP Reductase
C Neckles, S Eltschkner, JE Cummings, M Hirschbeck, F Daryaee, ...
Biochemistry 56 (13), 1865-1878, 2017
62017
Discovery of Novel Bruton’s Tyrosine Kinase PROTACs with Enhanced Selectivity and Cellular Efficacy
YQ Li, WG Lannigan, S Davoodi, F Daryaee, A Corrionero, P Alfonso, ...
Journal of Medicinal Chemistry 66 (11), 7454-7474, 2023
52023
A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure
S Eltschkner, J Kehrein, TA Le, S Davoodi, B Merget, S Basak, ...
ACS infectious diseases 7 (4), 746-758, 2021
42021
Evaluating the Impact of the Tyr158 pKa on the Mechanism and Inhibition of InhA, the Enoyl-ACP Reductase from Mycobacterium tuberculosis
S Davoodi, F Daryaee, JN Iuliano, J Tolentino Collado, YL He, AC Pollard, ...
Biochemistry 62 (12), 1943-1952, 2023
22023
Enhancers of innate and adaptive immunity combine with membrane bound IL15 to increase the efficacy of tumor infiltrating lymphocyte (TIL) therapy for tumors with …
C Passaro, B Koscso, S Smith, V Young, T Ross, B Primack, N Ly, ...
J. Immunother. Cancer https://doi. org/10.1136/jitc-2022-sitc2022 369, 2022
12022
Rational Optimization of Diphenyl Ether Binding Kinetics to the Enoyl-ACP Reductase FabI1 from Burkholderia pseudomallei
C Neckles, S Eltschkner, JE Cummings, M Hirschbeck, F Daryaee, ...
Biochemistry 56 (13), 1865, 2017
12017
Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity
MT Cifone, YL He, R Basu, N Wang, S Davoodi, LA Spagnuolo, Y Si, ...
Journal of medicinal chemistry 65 (24), 16510-16525, 2022
2022
Armoring T-Cells with Regulatable, Membrane Tethered Cytokines Using Improved Drug-Responsive Domain Technology (cytoDRIVE (TM))
DJ Li, S Davoodi, D Sun, S Smith, C Passaro, M Ols, J ter Meulen, D Sethi
MOLECULAR THERAPY 30 (4), 508-508, 2022
2022
Antibacterial Drug Discovery: Impact of Binding Kinetics and Target Vulnerability
S Davoodi
State University of New York at Stony Brook, 2019
2019
Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors
E Sandra, Y Weixuan, D Fereidoon, D Shabnam, AE KH, M Jonathan, ...
2017
Selectivity of Pyridone-and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase
N Carla, P Annica, L Cheng-Tsung, H Maria, K Jochen, D Shabnam, ...
2016
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