Evaluating the contribution of transition-state destabilization to changes in the residence time of triazole-based InhA inhibitors LA Spagnuolo, S Eltschkner, W Yu, F Daryaee, S Davoodi, SE Knudson, ... Journal of the American Chemical Society 139 (9), 3417-3429, 2017 | 52 | 2017 |
Correlating Drug–Target Residence Time and Post-antibiotic Effect: Insight into Target Vulnerability S Davoodi, F Daryaee, A Chang, SG Walker, PJ Tonge ACS infectious diseases 6 (4), 629-636, 2020 | 20 | 2020 |
Selectivity of Pyridone- and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase C Neckles, A Pschibul, CT Lai, M Hirschbeck, J Kuper, S Davoodi, J Zou, ... Biochemistry 55 (21), 2992-3006, 2016 | 10 | 2016 |
Rationalizing the Binding Kinetics for the Inhibition of the Burkholderia pseudomallei FabI1 Enoyl-ACP Reductase C Neckles, S Eltschkner, JE Cummings, M Hirschbeck, F Daryaee, ... Biochemistry 56 (13), 1865-1878, 2017 | 6 | 2017 |
Discovery of Novel Bruton’s Tyrosine Kinase PROTACs with Enhanced Selectivity and Cellular Efficacy YQ Li, WG Lannigan, S Davoodi, F Daryaee, A Corrionero, P Alfonso, ... Journal of Medicinal Chemistry 66 (11), 7454-7474, 2023 | 5 | 2023 |
A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure S Eltschkner, J Kehrein, TA Le, S Davoodi, B Merget, S Basak, ... ACS infectious diseases 7 (4), 746-758, 2021 | 4 | 2021 |
Evaluating the Impact of the Tyr158 pKa on the Mechanism and Inhibition of InhA, the Enoyl-ACP Reductase from Mycobacterium tuberculosis S Davoodi, F Daryaee, JN Iuliano, J Tolentino Collado, YL He, AC Pollard, ... Biochemistry 62 (12), 1943-1952, 2023 | 2 | 2023 |
Enhancers of innate and adaptive immunity combine with membrane bound IL15 to increase the efficacy of tumor infiltrating lymphocyte (TIL) therapy for tumors with … C Passaro, B Koscso, S Smith, V Young, T Ross, B Primack, N Ly, ... J. Immunother. Cancer https://doi. org/10.1136/jitc-2022-sitc2022 369, 2022 | 1 | 2022 |
Rational Optimization of Diphenyl Ether Binding Kinetics to the Enoyl-ACP Reductase FabI1 from Burkholderia pseudomallei C Neckles, S Eltschkner, JE Cummings, M Hirschbeck, F Daryaee, ... Biochemistry 56 (13), 1865, 2017 | 1 | 2017 |
Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity MT Cifone, YL He, R Basu, N Wang, S Davoodi, LA Spagnuolo, Y Si, ... Journal of medicinal chemistry 65 (24), 16510-16525, 2022 | | 2022 |
Armoring T-Cells with Regulatable, Membrane Tethered Cytokines Using Improved Drug-Responsive Domain Technology (cytoDRIVE (TM)) DJ Li, S Davoodi, D Sun, S Smith, C Passaro, M Ols, J ter Meulen, D Sethi MOLECULAR THERAPY 30 (4), 508-508, 2022 | | 2022 |
Antibacterial Drug Discovery: Impact of Binding Kinetics and Target Vulnerability S Davoodi State University of New York at Stony Brook, 2019 | | 2019 |
Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors E Sandra, Y Weixuan, D Fereidoon, D Shabnam, AE KH, M Jonathan, ... | | 2017 |
Selectivity of Pyridone-and Diphenyl Ether-Based Inhibitors for the Yersinia pestis FabV Enoyl-ACP Reductase N Carla, P Annica, L Cheng-Tsung, H Maria, K Jochen, D Shabnam, ... | | 2016 |