Substituted benzothiophene or benzofuran derivatives as a novel class of bone morphogenetic protein-2 up-regulators: synthesis, structure− activity relationships, and … H Guo, H Shao, Z Yang, S Xue, X Li, Z Liu, X He, J Jiang, Y Zhang, S Si, ... Journal of medicinal chemistry 53 (4), 1819-1829, 2010 | 83 | 2010 |
Rutaecarpine suppresses atherosclerosis in ApoE−/− mice through upregulating ABCA1 and SR-BI within RCT [S] Y Xu, Q Liu, Y Xu, C Liu, X Wang, X He, N Zhu, J Liu, Y Wu, Y Li, N Li, ... Journal of Lipid Research 55 (8), 1634-1647, 2014 | 63 | 2014 |
7-Glutathione pyrrole adduct: a potential DNA reactive metabolite of pyrrolizidine alkaloids Q Xia, L Ma, X He, L Cai, PP Fu Chemical research in toxicology 28 (4), 615-620, 2015 | 54 | 2015 |
Salidroside stimulates osteoblast differentiation through BMP signaling pathway JJ Chen, NF Zhang, GX Mao, XB He, YC Zhan, HB Deng, DQ Song, DD Li, ... Food and chemical toxicology 62, 499-505, 2013 | 54 | 2013 |
Detection of Pyrrolizidine Alkaloid DNA Adducts in Livers of Cattle Poisoned with Heliotropium europaeum PP Fu, Q Xia, X He, S Barel, N Edery, FA Beland, JA Shimshoni Chemical Research in Toxicology 30 (3), 851-858, 2017 | 35 | 2017 |
Mycophenolic acid induces adipocyte-like differentiation and reversal of malignancy of breast cancer cells partly through PPARγ ZH Zheng, Y Yang, XH Lu, H Zhang, XX Shui, C Liu, XB He, Q Jiang, ... European journal of pharmacology 658 (1), 1-8, 2011 | 33 | 2011 |
Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides X He, Q Xia, K Woodling, G Lin, PP Fu journal of food and drug analysis 25 (4), 984-991, 2017 | 29 | 2017 |
7-cysteine-pyrrole conjugate: A new potential DNA reactive metabolite of pyrrolizidine alkaloids X He, Q Xia, L Ma, PP Fu Journal of Environmental Science and Health, Part C 34 (1), 57-76, 2016 | 29 | 2016 |
Pyrrolizidine alkaloid secondary pyrrolic metabolites construct multiple activation pathways leading to DNA adduct formation and potential liver tumor initiation Q Xia, X He, L Ma, S Chen, PP Fu Chemical research in toxicology 31 (7), 619-628, 2018 | 28 | 2018 |
Identification of upregulators of BMP2 expression via high-throughput screening of a synthetic and natural compound library X Li, J Yang, X He, Z Yang, Y Ding, P Zhao, Z Liu, H Shao, Z Li, Y Zhang, ... SLAS Discovery 14 (10), 1251-1256, 2009 | 26 | 2009 |
7-Glutathione-pyrrole and 7-cysteine-pyrrole are potential carcinogenic metabolites of pyrrolizidine alkaloids X He, Q Xia, PP Fu Journal of Environmental Science and Health, Part C 35 (2), 69-83, 2017 | 24 | 2017 |
The determination of raloxifene in rat tissue using HPLC Z Yang, X He, Y Zhang Biomedical Chromatography 21 (3), 229-233, 2007 | 24 | 2007 |
The genotoxicity potential of luteolin is enhanced by CYP1A1 and CYP1A2 in human lymphoblastoid TK6 cells X Li, X He, S Chen, Y Le, MS Bryant, L Guo, KL Witt, N Mei Toxicology letters 344, 58-68, 2021 | 20 | 2021 |
Synthesis and evaluation of 1-(benzo [b] thiophen-2-yl) ethanone analogues as novel anti-osteoporosis agents acting on BMP-2 promotor Z Liu, X He, Z Yang, H Shao, X Li, H Guo, Y Zhang, S Si, Z Li Bioorganic & medicinal chemistry letters 19 (15), 4167-4170, 2009 | 18 | 2009 |
Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines X Li, X He, S Chen, X Guo, MS Bryant, L Guo, MG Manjanatha, T Zhou, ... Food and Chemical Toxicology 145, 111662, 2020 | 16 | 2020 |
Quantitation of DNA reactive pyrrolic metabolites of senecionine–A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis Q Xia, X He, Q Shi, G Lin, PP Fu journal of food and drug analysis 28 (1), 167-174, 2020 | 16 | 2020 |
7-N-Acetylcysteine-pyrrole conjugate—A potent DNA reactive metabolite of pyrrolizidine alkaloids X He, L Ma, Q Xia, PP Fu journal of food and drug analysis 24 (4), 682-694, 2016 | 14 | 2016 |
Development of a high-throughput screening strategy for upregulators of the OPG/RANKL ratio with the potential for antiosteoporosis effects S Gong, X Han, X Li, J Yang, X He, S Si Journal of Biomolecular Screening 21 (7), 738-748, 2016 | 13 | 2016 |
Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450s X Li, X He, Y Le, X Guo, MS Bryant, AH Atrakchi, TJ McGovern, ... Archives of Toxicology 96 (11), 3077-3089, 2022 | 12 | 2022 |
Evaluation of an in vitro three-dimensional HepaRG spheroid model for genotoxicity testing using the high-throughput CometChip platform JE Seo, X He, L Muskhelishvili, P Malhi, N Mei, M Manjanatha, M Bryant, ... Altex 39 (4), 2022 | 12 | 2022 |