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Xiaobo He
Xiaobo He
NCTR, FDA
Verified email at fda.hhs.gov
Title
Cited by
Cited by
Year
Substituted benzothiophene or benzofuran derivatives as a novel class of bone morphogenetic protein-2 up-regulators: synthesis, structure− activity relationships, and …
H Guo, H Shao, Z Yang, S Xue, X Li, Z Liu, X He, J Jiang, Y Zhang, S Si, ...
Journal of medicinal chemistry 53 (4), 1819-1829, 2010
832010
Rutaecarpine suppresses atherosclerosis in ApoE−/− mice through upregulating ABCA1 and SR-BI within RCT [S]
Y Xu, Q Liu, Y Xu, C Liu, X Wang, X He, N Zhu, J Liu, Y Wu, Y Li, N Li, ...
Journal of Lipid Research 55 (8), 1634-1647, 2014
632014
7-Glutathione pyrrole adduct: a potential DNA reactive metabolite of pyrrolizidine alkaloids
Q Xia, L Ma, X He, L Cai, PP Fu
Chemical research in toxicology 28 (4), 615-620, 2015
542015
Salidroside stimulates osteoblast differentiation through BMP signaling pathway
JJ Chen, NF Zhang, GX Mao, XB He, YC Zhan, HB Deng, DQ Song, DD Li, ...
Food and chemical toxicology 62, 499-505, 2013
542013
Detection of Pyrrolizidine Alkaloid DNA Adducts in Livers of Cattle Poisoned with Heliotropium europaeum
PP Fu, Q Xia, X He, S Barel, N Edery, FA Beland, JA Shimshoni
Chemical Research in Toxicology 30 (3), 851-858, 2017
352017
Mycophenolic acid induces adipocyte-like differentiation and reversal of malignancy of breast cancer cells partly through PPARγ
ZH Zheng, Y Yang, XH Lu, H Zhang, XX Shui, C Liu, XB He, Q Jiang, ...
European journal of pharmacology 658 (1), 1-8, 2011
332011
Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides
X He, Q Xia, K Woodling, G Lin, PP Fu
journal of food and drug analysis 25 (4), 984-991, 2017
292017
7-cysteine-pyrrole conjugate: A new potential DNA reactive metabolite of pyrrolizidine alkaloids
X He, Q Xia, L Ma, PP Fu
Journal of Environmental Science and Health, Part C 34 (1), 57-76, 2016
292016
Pyrrolizidine alkaloid secondary pyrrolic metabolites construct multiple activation pathways leading to DNA adduct formation and potential liver tumor initiation
Q Xia, X He, L Ma, S Chen, PP Fu
Chemical research in toxicology 31 (7), 619-628, 2018
282018
Identification of upregulators of BMP2 expression via high-throughput screening of a synthetic and natural compound library
X Li, J Yang, X He, Z Yang, Y Ding, P Zhao, Z Liu, H Shao, Z Li, Y Zhang, ...
SLAS Discovery 14 (10), 1251-1256, 2009
262009
7-Glutathione-pyrrole and 7-cysteine-pyrrole are potential carcinogenic metabolites of pyrrolizidine alkaloids
X He, Q Xia, PP Fu
Journal of Environmental Science and Health, Part C 35 (2), 69-83, 2017
242017
The determination of raloxifene in rat tissue using HPLC
Z Yang, X He, Y Zhang
Biomedical Chromatography 21 (3), 229-233, 2007
242007
The genotoxicity potential of luteolin is enhanced by CYP1A1 and CYP1A2 in human lymphoblastoid TK6 cells
X Li, X He, S Chen, Y Le, MS Bryant, L Guo, KL Witt, N Mei
Toxicology letters 344, 58-68, 2021
202021
Synthesis and evaluation of 1-(benzo [b] thiophen-2-yl) ethanone analogues as novel anti-osteoporosis agents acting on BMP-2 promotor
Z Liu, X He, Z Yang, H Shao, X Li, H Guo, Y Zhang, S Si, Z Li
Bioorganic & medicinal chemistry letters 19 (15), 4167-4170, 2009
182009
Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines
X Li, X He, S Chen, X Guo, MS Bryant, L Guo, MG Manjanatha, T Zhou, ...
Food and Chemical Toxicology 145, 111662, 2020
162020
Quantitation of DNA reactive pyrrolic metabolites of senecionine–A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis
Q Xia, X He, Q Shi, G Lin, PP Fu
journal of food and drug analysis 28 (1), 167-174, 2020
162020
7-N-Acetylcysteine-pyrrole conjugate—A potent DNA reactive metabolite of pyrrolizidine alkaloids
X He, L Ma, Q Xia, PP Fu
journal of food and drug analysis 24 (4), 682-694, 2016
142016
Development of a high-throughput screening strategy for upregulators of the OPG/RANKL ratio with the potential for antiosteoporosis effects
S Gong, X Han, X Li, J Yang, X He, S Si
Journal of Biomolecular Screening 21 (7), 738-748, 2016
132016
Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450s
X Li, X He, Y Le, X Guo, MS Bryant, AH Atrakchi, TJ McGovern, ...
Archives of Toxicology 96 (11), 3077-3089, 2022
122022
Evaluation of an in vitro three-dimensional HepaRG spheroid model for genotoxicity testing using the high-throughput CometChip platform
JE Seo, X He, L Muskhelishvili, P Malhi, N Mei, M Manjanatha, M Bryant, ...
Altex 39 (4), 2022
122022
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