PDX models recapitulate the genetic and epigenetic landscape of pediatric T‐cell leukemia P Richter‐Pechańska, JB Kunz, B Bornhauser, C von Knebel Doeberitz, ... EMBO molecular medicine 10 (12), e9443, 2018 | 47 | 2018 |
Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia J Roels, M Thénoz, B Szarzyńska, M Landfors, S De Coninck, L Demoen, ... Blood cancer discovery 1 (3), 274-289, 2020 | 27 | 2020 |
Functional analysis of structural variants in single cells using Strand-seq H Jeong, K Grimes, KK Rauwolf, PM Bruch, T Rausch, P Hasenfeld, ... Nature biotechnology 41 (6), 832-844, 2023 | 14 | 2023 |
Chromatin accessibility landscape of pediatric T‐lymphoblastic leukemia and human T‐cell precursors B Erarslan‐Uysal, JB Kunz, T Rausch, P Richter‐Pechańska, ... EMBO molecular medicine 12 (9), e12104, 2020 | 14 | 2020 |
Pediatric T-ALL type-1 and type-2 relapses develop along distinct pathways of clonal evolution P Richter-Pechańska, JB Kunz, T Rausch, B Erarslan-Uysal, ... Leukemia 36 (7), 1759-1768, 2022 | 5 | 2022 |
Haplotype-aware single-cell multiomics uncovers functional effects of somatic structural variation H Jeong, K Grimes, PM Bruch, T Rausch, P Hasenfeld, R Sabarinathan, ... bioRxiv, 2021.11. 11.468039, 2021 | 3 | 2021 |
P350: DAB1 EXPRESSION DRIVES PROLIFERATION AND METABOLIC ACTIVITY IN T-ALL AND INTERFERES WITH T-CELL-SPECIFIC PATHWAYS V Spleis, B Erarslan-Uysal, J Kunz, T Rausch, J Korbel, AE Kulozik HemaSphere 7 (S3), e39481d9, 2023 | | 2023 |
P333: SUBCLONAL AND CLONAL VARIANTS IN TP53 AND KRAS COMBINED WITH POOR TREATMENT RESPONSE IDENTIFY A SUBGROUP OF ULTRA-HIGH-RISK PATIENTS OF PEDIATRIC T-LYMPHOBLASTIC LEUKEMIA … T Kempter, P Richter-Pechanska, K Michel, T Rausch, B Erarslan-Uysal, ... HemaSphere 7 (S3), e9493074, 2023 | | 2023 |
The combination of subclonal and clonal TP53 and KRAS alterations and poor response to first line therapy identifies ultra-high-risk patients with pediatric T-lymphoblastic … T Kempter, P Richter-Pechanska, K Michel, T Rausch, B Erarslan-Uysal, ... | | 2023 |
S108: PEDIATRIC T-ALL RELAPSE: CONSTITUTIONAL CANCER PREDISPOSITION AND HYPERMUTATATOR PHENOTYPES P Richter-Pechanska, J Kunz, T Rausch, B Erarslan-Uysal, B Bornhauser, ... HemaSphere 6, 9-10, 2022 | | 2022 |
TP53 and KRAS Variants at Initial Diagnosis Identify an Ultra-High Risk Group of Pediatric T-Lymphoblastic Leukemia (T-ALL) T Kempter, JB Kunz, P Richter-Pechanska, K Tomska, T Rausch, ... Blood 138 (Supplement 1), 1315-1315, 2021 | | 2021 |
Longitudinal Multilevel Omic Analysis of Pediatric T-ALL Reveals Distinct Mechanisms for Disease Progression in Type 1 and in Type 2 Relapses P Richter-Pechanska, JB Kunz, T Rausch, B Erarslan-Uysal, ... Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | | 2018 |
Pediatric T-ALLs Developing into a Type 2 Relapse Originate from Cells That Carry the Potential of Variable Maturation into Subclones with Distinct Chromatin Landscapes B Erarslan-Uysal, JB Kunz, T Rausch, P Richter-Pechanska, S Waszak, ... Blood 132, 1545, 2018 | | 2018 |