Cell death mechanisms of neurodegeneration J Fan, TM Dawson, VL Dawson Neurodegenerative diseases: Pathology, mechanisms, and potential therapeutic …, 2017 | 121 | 2017 |
Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease J Fan, CM Cowan, LYJ Zhang, MR Hayden, LA Raymond Journal of Neuroscience 29 (35), 10928-10938, 2009 | 119 | 2009 |
P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease J Fan, CM Gladding, L Wang, LYJ Zhang, AM Kaufman, AJ Milnerwood, ... Neurobiology of disease 45 (3), 999-1009, 2012 | 105 | 2012 |
Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity JC Xu, J Fan, X Wang, SM Eacker, TI Kam, L Chen, X Yin, J Zhu, Z Chi, ... Science translational medicine 8 (333), 333ra48-333ra48, 2016 | 91 | 2016 |
Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice AJ Milnerwood, AM Kaufman, MD Sepers, CM Gladding, L Zhang, ... Neurobiology of disease 48 (1), 40-51, 2012 | 90 | 2012 |
Polyglutamine-modulated striatal calpain activity in YAC transgenic huntington disease mouse model: impact on NMDA receptor function and toxicity CM Cowan, MMY Fan, J Fan, J Shehadeh, LYJ Zhang, RK Graham, ... Journal of Neuroscience 28 (48), 12725-12735, 2008 | 85 | 2008 |
N‐Methyl‐d‐aspartate receptor subunit‐ and neuronal‐type dependence of excitotoxic signaling through post‐synaptic density 95 J Fan, OC Vasuta, LYJ Zhang, L Wang, A George, LA Raymond Journal of neurochemistry 115 (4), 1045-1056, 2010 | 43 | 2010 |
Alterations in STriatal‐Enriched protein tyrosine Phosphatase expression, activation, and downstream signaling in early and late stages of the YAC 128 Huntington's disease … CM Gladding, J Fan, LYJ Zhang, L Wang, J Xu, EHY Li, PJ Lombroso, ... Journal of neurochemistry 130 (1), 145-159, 2014 | 31 | 2014 |
Decreasing levels of the cdk5 activators, p25 and p35, reduces excitotoxicity in striatal neurons KHJ Park, G Lu, J Fan, LA Raymond, BR Leavitt Journal of Huntington's disease 1 (1), 89-96, 2012 | 10 | 2012 |
Neurodegenerative Diseases: Pathology, Mechanisms, and Potential Therapeutic Targets J Fan, TM Dawson, VL Dawson, P Beart, M Robinson, M Rattray, ... | 6 | 2017 |
Proliferating neural precursor cells as first step toward neuroregeneration in Huntington's disease? MMY Fan, J Fan Journal of Neuroscience 26 (52), 13411-13412, 2006 | 3 | 2006 |
Histone H1. 2 Dependent Translocation of Poly (ADP-ribose) Initiates Parthanatos J Fan, BG Kang, TI Kam, AA Behensky, J Rines, HC Kang, VL Dawson, ... bioRxiv, 2023.06. 18.545460, 2023 | | 2023 |
Signaling pathways involved in enhanced NMDA receptor-dependent excitotoxicity in a mouse model of Huntington disease J Fan University of British Columbia, 2011 | | 2011 |
Role of SAP102 in mutant Huntingtin-mediated regulation of NMDA receptor function in the YAC transgenic mouse model of Huntington Disease J Fan University of British Columbia, 2007 | | 2007 |