| RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly MSY Huen, R Grant, I Manke, K Minn, X Yu, MB Yaffe, J Chen Cell 131 (5), 901-914, 2007 | 1173 | 2007 |
| PALB2 is an integral component of the BRCA complex required for homologous recombination repair SMH Sy, MSY Huen, J Chen Proceedings of the National Academy of Sciences 106 (17), 7155-7160, 2009 | 700 | 2009 |
| BRCA1 and its toolbox for the maintenance of genome integrity MSY Huen, SMH Sy, J Chen Nature reviews Molecular cell biology 11 (2), 138-148, 2010 | 655 | 2010 |
| RAD18 transmits DNA damage signalling to elicit homologous recombination repair J Huang, MSY Huen, H Kim, CCY Leung, JNM Glover, X Yu, J Chen Nature cell biology 11 (5), 592-603, 2009 | 334 | 2009 |
| Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi KM Hui, MSY Huen, HY Wang, H Zheng, E Sigel, R Baur, H Ren, ZW Li, ... Biochemical pharmacology 64 (9), 1415-1424, 2002 | 321 | 2002 |
| The DNA damage response pathways: at the crossroad of protein modifications MSY Huen, J Chen Cell research 18 (1), 8-16, 2008 | 265 | 2008 |
| Histone ubiquitination associates with BRCA1-dependent DNA damage response J Wu, MSY Huen, LY Lu, L Ye, Y Dou, M Ljungman, J Chen, X Yu Molecular and cellular biology 29 (3), 849-860, 2009 | 164 | 2009 |
| Direct interaction between SET8 and proliferating cell nuclear antigen couples H4-K20 methylation with DNA replication MSY Huen, SMH Sy, JM Van Deursen, J Chen Journal of biological chemistry 283 (17), 11073-11077, 2008 | 140 | 2008 |
| Assembly of checkpoint and repair machineries at DNA damage sites MSY Huen, J Chen Trends in biochemical sciences 35 (2), 101-108, 2010 | 134 | 2010 |
| PALB2 regulates recombinational repair through chromatin association and oligomerization SMH Sy, MSY Huen, Y Zhu, J Chen Journal of biological chemistry 284 (27), 18302-18310, 2009 | 116 | 2009 |
| Anxiolytic-like action of orally administered dl-tetrahydropalmatine in elevated plus-maze WC Leung, H Zheng, M Huen, SL Law, H Xue Progress in Neuro-Psychopharmacology and Biological Psychiatry 27 (5), 775-779, 2003 | 110 | 2003 |
| Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8 MA Santos, MSY Huen, M Jankovic, HT Chen, AJ López-Contreras, ... Journal of Experimental Medicine 207 (5), 973-981, 2010 | 107 | 2010 |
| 5, 7-Dihydroxy-6-methoxyflavone, a benzodiazepine site ligand isolated from Scutellaria baicalensis Georgi, with selective antagonistic properties MSY Huen, JWC Leung, W Ng, WS Lui, MNS Chan, JTF Wong, H Xue Biochemical pharmacology 66 (1), 125-132, 2003 | 103 | 2003 |
| Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis K Minter-Dykhouse, I Ward, MSY Huen, J Chen, Z Lou The Journal of cell biology 181 (5), 727-735, 2008 | 100 | 2008 |
| Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair JWC Leung, Y Wang, KW Fong, MSY Huen, L Li, J Chen Proceedings of the National Academy of Sciences 109 (12), 4491-4496, 2012 | 93 | 2012 |
| Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1 MSY Huen, J Huang, JWC Leung, SMH Sy, KM Leung, YP Ching, ... Molecular cell 37 (6), 854-864, 2010 | 93 | 2010 |
| MRG15 is a novel PALB2-interacting factor involved in homologous recombination SMH Sy, MSY Huen, J Chen Journal of Biological Chemistry 284 (32), 21127-21131, 2009 | 93 | 2009 |
| The E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection R Rai, JM Li, H Zheng, GTM Lok, Y Deng, MSY Huen, J Chen, J Jin, ... Nature structural & molecular biology 18 (12), 1400-1407, 2011 | 85 | 2011 |
| PRMT6 regulates RAS/RAF binding and MEK/ERK-mediated cancer stemness activities in hepatocellular carcinoma through CRAF methylation LH Chan, L Zhou, KY Ng, TL Wong, TK Lee, R Sharma, JH Loong, ... Cell reports 25 (3), 690-701. e8, 2018 | 81 | 2018 |
| Ring finger protein RNF169 antagonizes the ubiquitin-dependent signaling cascade at sites of DNA damage J Chen, W Feng, J Jiang, Y Deng, MSY Huen Journal of Biological Chemistry 287 (33), 27715-27722, 2012 | 74 | 2012 |
