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Zhongwu Lai
Zhongwu Lai
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
The sequence of the human genome
JC Venter, MD Adams, EW Myers, PW Li, RJ Mural, GG Sutton, HO Smith, ...
science 291 (5507), 1304-1351, 2001
201722001
The Genome Sequence of Drosophila melanogaster
MD Adams, SE Celniker, RA Holt, CA Evans, JD Gocayne, ...
Science 287 (5461), 2185-2195, 2000
81932000
The Genome Sequence of the Malaria Mosquito Anopheles gambiae
RA Holt, GM Subramanian, A Halpern, GG Sutton, R Charlab, ...
science 298 (5591), 129-149, 2002
25462002
A Whole-Genome Assembly of Drosophila
EW Myers, GG Sutton, AL Delcher, IM Dew, DP Fasulo, MJ Flanigan, ...
Science 287 (5461), 2196-2204, 2000
21252000
Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M
KS Thress, CP Paweletz, E Felip, BC Cho, D Stetson, B Dougherty, Z Lai, ...
Nature medicine 21 (6), 560-562, 2015
15132015
VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research
Z Lai, A Markovets, M Ahdesmaki, B Chapman, O Hofmann, R McEwen, ...
Nucleic acids research 44 (11), e108-e108, 2016
7632016
Comparative Genome and Proteome Analysis of Anopheles gambiae and Drosophila melanogaster
EM Zdobnov, C Von Mering, I Letunic, D Torrents, M Suyama, RR Copley, ...
science 298 (5591), 149-159, 2002
6082002
Chromosome 2 Sequence of the Human Malaria Parasite Plasmodium falciparum
MJ Gardner, H Tettelin, DJ Carucci, LM Cummings, L Aravind, EV Koonin, ...
Science 282 (5391), 1126-1132, 1998
5821998
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome
RJ Mural, MD Adams, EW Myers, HO Smith, GLG Miklos, R Wides, ...
Science 296 (5573), 1661-1671, 2002
4852002
Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells
H Dev, TWW Chiang, C Lescale, I de Krijger, AG Martin, D Pilger, ...
Nature cell biology 20 (8), 954-965, 2018
3532018
Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA): an open-label, multicentre, phase 1/2, basket study
SM Domchek, S Postel-Vinay, SA Im, YH Park, JP Delord, A Italiano, ...
The Lancet Oncology 21 (9), 1155-1164, 2020
3302020
Acquired resistance to the mutant-selective EGFR inhibitor AZD9291 is associated with increased dependence on RAS signaling in preclinical models
CA Eberlein, D Stetson, AA Markovets, KJ Al-Kadhimi, Z Lai, PR Fisher, ...
Cancer research 75 (12), 2489-2500, 2015
3172015
Human chromosome 7: DNA sequence and biology
SW Scherer, J Cheung, JR MacDonald, LR Osborne, K Nakabayashi, ...
Science 300 (5620), 767-772, 2003
2682003
Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes
DR Hodgson, BA Dougherty, Z Lai, A Fielding, L Grinsted, S Spencer, ...
British journal of cancer 119 (11), 1401-1409, 2018
2052018
Discovery and mechanistic study of a small molecule inhibitor for motor protein KIFC1
J Wu, K Mikule, W Wang, N Su, P Petteruti, F Gharahdaghi, E Code, X Zhu, ...
ACS chemical biology 8 (10), 2201-2208, 2013
1612013
Mechanism and In Vitro Pharmacology of TAK1 Inhibition by (5Z)-7-Oxozeaenol
J Wu, F Powell, NA Larsen, Z Lai, KF Byth, J Read, RF Gu, M Roth, ...
ACS chemical biology 8 (3), 643-650, 2013
1572013
The combination of the PARP inhibitor olaparib and the WEE1 inhibitor AZD1775 as a new therapeutic option for small cell lung cancer
A Lallo, KK Frese, CJ Morrow, R Sloane, S Gulati, MW Schenk, F Trapani, ...
Clinical Cancer Research 24 (20), 5153-5164, 2018
1462018
Long-term responders on olaparib maintenance in high-grade serous ovarian cancer: clinical and molecular characterization
S Lheureux, Z Lai, BA Dougherty, S Runswick, DR Hodgson, KM Timms, ...
Clinical Cancer Research 23 (15), 4086-4094, 2017
1332017
A shotgun optical map of the entire Plasmodium falciparum genome
Z Lai, J Jing, C Aston, V Clarke, J Apodaca, ET Dimalanta, DJ Carucci, ...
nature genetics 23 (3), 309-313, 1999
1321999
Defining actionable mutations for oncology therapeutic development
TH Carr, R McEwen, B Dougherty, JH Johnson, JR Dry, Z Lai, Z Ghazoui, ...
Nature Reviews Cancer 16 (5), 319-329, 2016
1122016
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