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Guillaume Cognet
Guillaume Cognet
Verified email at uchicago.edu
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Year
Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia
L Stuani, M Sabatier, E Saland, G Cognet, N Poupin, C Bosc, FA Castelli, ...
Journal of Experimental Medicine 218 (5), e20200924, 2021
742021
Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia
C Bosc, E Saland, A Bousard, N Gadaud, M Sabatier, G Cognet, T Farge, ...
Nature cancer 2 (11), 1204-1223, 2021
622021
C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress–Induced Ferroptosis in FLT3-Mutant Leukemia
M Sabatier, R Birsen, L Lauture, S Mouche, P Angelino, J Dehairs, ...
Cancer Discovery 13 (7), 1720-1747, 2023
252023
CD36 drives metastasis and relapse in acute myeloid leukemia
T Farge, J Nakhle, D Lagarde, G Cognet, N Polley, R Castellano, ...
Cancer Research 83 (17), 2824-2838, 2023
132023
Activation of vitamin D receptor pathway enhances differentiating capacity in acute myeloid leukemia with isocitrate dehydrogenase mutations
M Sabatier, E Boet, S Zaghdoudi, N Guiraud, A Hucteau, N Polley, ...
Cancers 13 (20), 5243, 2021
92021
C/EBPα confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress in FLT3-mutant leukemia
M Sabatier, R Birsen, L Lauture, J Dehairs, P Angelino, S Mouche, ...
bioRxiv, 2022.04. 15.488522, 2022
22022
Mitochondrial determinants of response and resistance to venetoclax plus cytarabine duplet therapy in acute myeloid leukemia
C Bosc, N Gadaud, A Bousard, M Sabatier, G Cognet, E Saland, T Farge, ...
BioRxiv, 2020.08. 17.253856, 2020
22020
Combinatory therapy targeting mitochondrial oxidative phosphorylation improves efficacy of IDH mutant inhibitors in acute myeloid leukemia
L Stuani, M Sabatier, F Wang, N Poupin, C Bosc, E Saland, F Castelli, ...
bioRxiv, 749580, 2019
12019
Abstract PR14: Ex vivo models of pancreatic cancer that recapitulate the metabolic tumor microenvironment identify glycine as a chemoresistance-inducing …
G Cognet, C Sheehan, G Croley, L Hu, A Muir
Cancer Research 84 (2_Supplement), PR14-PR14, 2024
2024
Ex vivo models of pancreatic cancer that recapitulate the metabolic tumor microenvironment identify glycine as a chemoresistance-inducing oncometabolite
G Cognet, C Sheehan, G Croley, L Hu, A Muir
CANCER RESEARCH 84 (2), 2024
2024
Etude des adaptations métaboliques tissulaires et systémiques dans les leucémies aigues myéloides
G Cognet
Université Paul Sabatier-Toulouse III, 2021
2021
METAML-IDENTIFICATION MULTI-OMIQUES DE CIBLES METABOLIQUES INNOVANTES ET PREDICTIVES DE LA RESISTANCE A LA CYTARABINE DANS LES LEUCEMIES AIGUES MYELOIDES
G Cognet
2021
In vivo metabolomic study uncovers distinct metabolic phenotypes of host tissues and predicts oxidative state of acute myeloid leukemia
G Cognet, L Stuani, T Farge, M Gotanègre, M Heuillet, L Gales, A Rocher, ...
2021
Combinatory therapy targeting mitochondrial oxidative phosphorylation improves
M Conti12, S Loric12, PL Mouchel, M Gotanègre, C Cassan14, ...
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