Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia L Stuani, M Sabatier, E Saland, G Cognet, N Poupin, C Bosc, FA Castelli, ... Journal of Experimental Medicine 218 (5), e20200924, 2021 | 74 | 2021 |
Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia C Bosc, E Saland, A Bousard, N Gadaud, M Sabatier, G Cognet, T Farge, ... Nature cancer 2 (11), 1204-1223, 2021 | 62 | 2021 |
C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress–Induced Ferroptosis in FLT3-Mutant Leukemia M Sabatier, R Birsen, L Lauture, S Mouche, P Angelino, J Dehairs, ... Cancer Discovery 13 (7), 1720-1747, 2023 | 25 | 2023 |
CD36 drives metastasis and relapse in acute myeloid leukemia T Farge, J Nakhle, D Lagarde, G Cognet, N Polley, R Castellano, ... Cancer Research 83 (17), 2824-2838, 2023 | 13 | 2023 |
Activation of vitamin D receptor pathway enhances differentiating capacity in acute myeloid leukemia with isocitrate dehydrogenase mutations M Sabatier, E Boet, S Zaghdoudi, N Guiraud, A Hucteau, N Polley, ... Cancers 13 (20), 5243, 2021 | 9 | 2021 |
C/EBPα confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress in FLT3-mutant leukemia M Sabatier, R Birsen, L Lauture, J Dehairs, P Angelino, S Mouche, ... bioRxiv, 2022.04. 15.488522, 2022 | 2 | 2022 |
Mitochondrial determinants of response and resistance to venetoclax plus cytarabine duplet therapy in acute myeloid leukemia C Bosc, N Gadaud, A Bousard, M Sabatier, G Cognet, E Saland, T Farge, ... BioRxiv, 2020.08. 17.253856, 2020 | 2 | 2020 |
Combinatory therapy targeting mitochondrial oxidative phosphorylation improves efficacy of IDH mutant inhibitors in acute myeloid leukemia L Stuani, M Sabatier, F Wang, N Poupin, C Bosc, E Saland, F Castelli, ... bioRxiv, 749580, 2019 | 1 | 2019 |
Abstract PR14: Ex vivo models of pancreatic cancer that recapitulate the metabolic tumor microenvironment identify glycine as a chemoresistance-inducing … G Cognet, C Sheehan, G Croley, L Hu, A Muir Cancer Research 84 (2_Supplement), PR14-PR14, 2024 | | 2024 |
Ex vivo models of pancreatic cancer that recapitulate the metabolic tumor microenvironment identify glycine as a chemoresistance-inducing oncometabolite G Cognet, C Sheehan, G Croley, L Hu, A Muir CANCER RESEARCH 84 (2), 2024 | | 2024 |
Etude des adaptations métaboliques tissulaires et systémiques dans les leucémies aigues myéloides G Cognet Université Paul Sabatier-Toulouse III, 2021 | | 2021 |
METAML-IDENTIFICATION MULTI-OMIQUES DE CIBLES METABOLIQUES INNOVANTES ET PREDICTIVES DE LA RESISTANCE A LA CYTARABINE DANS LES LEUCEMIES AIGUES MYELOIDES G Cognet | | 2021 |
In vivo metabolomic study uncovers distinct metabolic phenotypes of host tissues and predicts oxidative state of acute myeloid leukemia G Cognet, L Stuani, T Farge, M Gotanègre, M Heuillet, L Gales, A Rocher, ... | | 2021 |
Combinatory therapy targeting mitochondrial oxidative phosphorylation improves M Conti12, S Loric12, PL Mouchel, M Gotanègre, C Cassan14, ... | | |